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This systematic review evaluates preclinical and clinical evidence on glucagon-like peptide-1 receptor agonists as potential treatments for substance use disorders. Findings show consistent reductions in drug- and alcohol-seeking behaviors in animal models, while human evidence remains limited, heterogeneous, and preliminary.

Natural ovulation before frozen embryo transfer is as effective as hormone treatment for achieving a healthy baby by vitro fertilization (IVF), finds a clinical trial from China published by The BMJ today.

Offering non-monetary incentives such as free access to outpatient consultations to frequent blood donors is linked to an increase in donations without compromising blood safety, finds a study from China published by The BMJ today.

Gaps in the nation's stroke transfer system are drastically reducing survivors' chances of receiving critical treatment and increasing the likelihood that they will leave the hospital with a disability, a new study suggests.

There has been a lasting and disproportionate impact of the Covid-19 pandemic on diagnosis rates for conditions including depression, asthma and osteoporosis.

Severe vitamin D deficiency is associated with a higher rate of hospitalization for respiratory tract infections such as bronchitis and pneumonia, according to a new study led by the University of Surrey.

Long-term exposure to ambient air pollution was associated with a higher risk of developing motor neuron disease and poorer prognosis after diagnosis in a large nationwide Swedish study. Higher particulate matter and nitrogen dioxide exposure were also linked to faster functional decline and increased likelihood of invasive ventilation.

Australians undergoing open-heart surgery could soon benefit from safer, simpler care and get home earlier thanks to the results of a world-first clinical trial led by Monash University's Victorian Heart Institute.

This population-based study of U.S. adults aged 70 and older found that shingles vaccination was associated with slower epigenetic and transcriptomic aging, as well as lower systemic inflammation. No significant associations were observed for neurodegeneration or cardiovascular biomarkers, highlighting domain-specific molecular effects rather than broad clinical changes.

In a UK pilot randomized trial, intravenous paracetamol and ibuprofen showed no statistically significant differences in short-term efficacy or safety when used as rescue therapy for hemodynamically significant patent ductus arteriosus in very preterm infants. The study demonstrated high feasibility but was not powered to determine clinical superiority or equivalence between treatments.

People who have ADHD traits at age 10 are more likely than those without such traits to have physical health problems and to report physical health-related disability at age 46, according to a study led by University College London (UCL) and University of Liverpool researchers.

Metabolic dysfunction-associated steatotic liver disease (MASLD) and its progressive form, metabolic dysfunction-associated steatohepatitis (MASH), represent the most common chronic liver diseases in Western populations, driven largely by obesity and insulin resistance.

Despite improvements in economic and social empowerment, women in many countries still have little control over their own fertility and reproductive health.

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study investigated the association between serum uric acid (UA) levels and atrial fibrillation (AF) burden in Chinese patients with AF.

Most research on the health effects of stress focuses on adults, but a new review looks at how stress uniquely affects children.

A new doctoral dissertation shows that gambling disorder is linked to brain networks involved in self-control and brain reward functions.

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Transglutaminase 2 (TGM2) has been implicated in various health conditions, yet its role in acute coronary syndrome (ACS) remains poorly characterized in clinical settings.

Physical rehabilitation and symptom management still remain the mainstay of treatment for stroke, as clot removal or dissolution is effective only within a narrow time frame after the stroke.

Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), and Duke University have proposed a neuroscience framework explaining how different types of motivation fundamentally reshape what and how the brain remembers.

Adrenocortical carcinoma (ACC) is a rare but aggressive malignancy with high postoperative recurrence rates and poor prognosis. Mitotane remains the only approved agent for ACC, exerting antitumor effects by disrupting mitochondrial integrity, inhibiting steroidogenic enzymes, and interfering with cholesterol metabolism.