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New research shines light on position-specific hallmarks of cancer
A team led by the Cancer Immunogenomics group at the Josep Carreras Leukaemia Research Institute, the Computational Biology group at the Barcelona Supercomputing Center and the Germans Trias i Pujol Research Institute shows, for the first time, that within a tumor, the expression of the different hallmarks of cancer is not cell-specific, but rather position-specific.
Study explores long-term effects of Japan's COVID-19 health advisories
In contrast to the lockdowns imposed in many countries around the world during the COVID-19 pandemic, the Japanese authorities issued health advisories and counted on citizens to follow them voluntarily.
New insights into mechanisms of mucosal mast cells in food allergies
Food allergy, or the aggressive immune system reaction following the consumption of a certain food or food ingredient, typically involves immunoglobulin E (IgE) antibodies and can be potentially life-threatening
Targeting MYCN and MDM2 offers new hope for cancer therapy
Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.
New study compares dementia care approaches and the impact on caregivers
New research comparing different approaches to dementia care for people with Alzheimer's disease and other dementias found no significant differences in patient behavioral symptoms or caregiver strain, whether delivered through a health system, provided by a community-based organization, or as usual care over an 18-month period.
University of Oklahoma researcher leads efforts to unravel mysteries of cognitive decline
An estimated 76,000 Oklahomans are living with Alzheimer's disease, a number that has surged by 13% in just five years. Yet, despite the increasing need for effective treatments, therapies for age-related dementia have largely failed to slow or halt the disease's progression.
Climate change is pushing up rates of kidney disease and urological cancers
Climate change is increasing the risk of urological diseases, including cancer and kidney conditions, while urological healthcare itself contributes to environmental harm through high carbon emissions.
Study reveals how glial cells respond to damage in neuron dendrites
Neurons may get all the glory, but they would be nothing without glial cells. While brain cells do the heavy lifting in the nervous system, it's the glia that provide nutrients, clean up waste, and protect neurons from harm.
Map highlights diagnosis gaps for deadly CNS infections in HIV patients in Africa
A map of deadly infectious diseases known to attack the central nervous system (CNS) of people who are already suffering with HIV has unearthed diagnosis "blank spots" in Africa, according to research published today in The Lancet Global Health .
Breakthrough study highlights role of prenatal supplements in preventing infant mortality
Dongqing Wang, an assistant professor of Global and Community Health at George Mason's College of Public Health, is pioneering research in prenatal nutritional interventions.
Is juicing good for your gut? Research shows surprising microbiome changes
Short-term fruit and vegetable juicing causes microbial shifts in the oral and gut microbiome, but these changes are mostly transient and return to baseline after 14 days.
Research highlights differences in how hospitals diagnose appendicitis in children
Abdominal pain is among the most common reasons children are taken to the emergency department.
Study reveals strong link between childhood trauma and adolescent psychiatric disorders
A new study by a team of researchers from the UK and Brazil has revealed a strong connection between childhood trauma and the development of psychiatric disorders in adolescents living in low-and middle-income countries.
Chiropractic spinal manipulation reduces opioid risks for sciatica patients
A new study led by researchers at University Hospitals Connor Whole Health found that adults with newly diagnosed sciatica who initially received chiropractic spinal manipulation (CSM) were significantly less likely to experience opioid-related adverse drug events (ORADEs) such as overdose and poisoning over a one-year follow-up compared to those receiving usual medical care.
Study reveals pandemic’s effects on social skills of young children
Lockdowns. Social distancing. Shuttered schools and businesses. The COVID-19 pandemic and its sweeping disruptions set off a stampede of "what it's doing to us" research, focused largely on schoolchildren.
Fluctuating cholesterol linked to higher risk of dementia in older adults
Older adults whose cholesterol changes over time may be more likely to develop dementia than people whose cholesterol is stable, regardless of the actual cholesterol level, according to a study published in the January 29, 2025, online issue of Neurology, the medical journal of the American Academy of Neurology.
From gut health to metabolism: How sleep controls more than you think
Study reveals that sleep traits predict over 15% of body characteristics across 15 physiological systems, with visceral fat, cardiovascular health, and metabolism deeply intertwined with sleep patterns.
Weekly diabetes injection could replace daily shots for lipodystrophy patients
Rutgers Health researchers have found that a weekly injection of diabetes medication could replace painful daily hormone shots for people with a rare genetic form of lipodystrophy that leaves patients with almost zero fat tissue, according to a study in The New England Journal of Medicine.
Mayo Clinic researchers create organoid models for uveal melanoma study
Mayo Clinic researchers have developed organoid models to study uveal melanoma, one of the most common types of eye cancer in adults.
Can an online lifestyle plan keep your brain sharp? Research says yes
"Maintain Your Brain" study shows how a tailored online program can improve cognition and lower dementia risk—discover how simple lifestyle changes could protect your brain as you age.