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Researchers mapped more than 11,000 transcriptomes across mice, rats, macaques, and humans, revealing conserved molecular signatures of aging and mortality across tissues, species, and cell types. The study developed interpretable transcriptomic clocks that track age, mortality-related molecular change, chronic disease signals and responses to lifespan-altering interventions.

A large Swedish prospective cohort study found that specific gut microbial species and metabolic pathways measured years before diagnosis were associated with future type 2 diabetes risk. The findings suggest that gut microbiome composition and functional potential may help explain T2D development, but replication is needed before clinical use.

When a person has a new experience, their brain faces a subtle but critical decision: should this experience be categorized with other stored memories, or should it be filed away as its own new memory? Getting it right allows the brain to help people navigate the world.

Researchers found that women who had undergone colorectal adenoma resection still showed gut microbiome and fecal metabolome alterations an average of about 12 years later. These persistent changes partly resembled colorectal cancer-associated patterns, suggesting that the host-microbiome axis may remain altered along the adenoma-cancer continuum.

A new study from researchers at the Child Mind Institute finds that negative online experiences are common among children and adolescents with mental health and neurodevelopmental conditions, and that most incidents are not reported through platform reporting tools.

MR-AIV uses physics-informed AI and DCE-MRI scans to infer 3D brain-wide fluid movement in mice without direct flow measurements. The method distinguished slow diffusion-dominated transport from faster advective flow and estimated pressure and permeability patterns linked to brain waste clearance.

Obesity may change how early-stage breast cancer becomes invasive, according to a study by University of Oklahoma researchers published in The American Journal of Pathology.

Researchers at the University of Cincinnati College of Medicine have found that patients who continue to smoke ahead of lung cancer surgery have a higher risk of pulmonary complications, but their short-term mortality rate is similar to patients who were able to stop smoking before surgery.

Researchers have found that consuming lower amounts of protein-rich foods may negatively affect physical functioning as people grow older, underscoring the vital function protein plays in preserving mobility and muscle strength in adulthood.

More than a quarter of women buying menstrual products also purchase pain relief at the same time-and those in lower-income areas are significantly less likely to do so-according to a new study published this week in the open-access journal PLOS Digital Health by Dr. Victoria Sivill of the University of Bristol, UK, and colleagues, which used supermarket loyalty card data to map menstrual pain disparities across England.

Researchers at LSU's Pennington Biomedical Research Center, in collaboration with investigators from 32 countries participating in the SUNRISE International Study, have published new findings examining how restrained sitting contributes to daily movement patterns in early childhood.

Diagnostic interviews are widely used by mental health professionals to identify conditions such as anxiety, bipolar disorder and depression in adults, but new research led by McMaster University shows that the long considered "gold standard" may not be as consistent as previously thought.

A Mount Sinai-led research team has demonstrated that autoimmunity, where the body's immune system attacks its own tissues, is responsible for the often-debilitating and confounding symptoms of long COVID in a subset of people.

Chronic oral inflammation may impair female fertility by triggering a systemic immune response that affects the ovaries.

Researchers at Columbia University Irving Medical Center have identified a gene that drives the development of neuroendocrine prostate cancer (NEPC), an aggressive form of the disease.

Researchers from the University of Cambridge highlight new ways that neurons and many cell types use to sense nutrients - opening potential novel therapeutic avenues for disorders such as Alzheimer's and Parkinson's disease.

Weill Cornell Medicine received a five-year, $5 million grant from the National Cancer Institute, part of the National Institutes of Health, to develop innovative support strategies for an understudied group of cancer patients: adolescents and young adults (AYAs).

A recent study from The University of Texas at San Antonio reveals that low-cost training for frontline health workers can significantly reduce medical supply shortages, potentially saving thousands of lives in developing nations.

Your heart already has its own built-in bypass system that predicts whether the heart muscle is alive or dead - according to new research from the University of East Anglia and Norfolk and Norwich University Hospital.

Living cells cool much slower than our current understanding of heat conduction can explain, according to new research from the University of Tokyo. Researchers used two techniques - high-speed temperature mapping and artificial heating - to observe how heat dissipated from living cells and similar-sized artificial, fluid-filled sacs (liposomes).