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When harmful bacteria that cause food poisoning, such as E. coli, invade through the digestive tract, gut cells usually fight back by pushing infected cells out of the body to stop the infection from spreading.

Nearly half of all babies born with Down syndrome face congenital heart defects, often involving serious malformations that require surgery in the first months of life.

Scientists at the Ruđer Bošković Institute (RBI) in Zagreb, Croatia, have discovered that the protein CENP-E, long believed to act as a motor dragging chromosomes into place during cell division, in fact plays a completely different role in chromosome movement.

Antidepressants can differ widely in how they physically affect the body, including around a 4 kg difference in weight change between certain drugs (approximately 2.5 kg weight loss from agomelatine and 2kg weight gain from maprotiline), confirms a systematic review and meta-analysis published in The Lancet.

Less than half of schoolchildren in England who are at risk of a serious and potentially life-threatening allergic reaction (anaphylaxis) to food were prescribed the antidote-an adrenaline [epinephrine] autoinjector, or AAI for short-finds an analysis of national prescribing data, published online in the Archives of Disease in Childhood.

Lab-based studies have provided lots of information on the biology of aging, but it's unclear how lab discoveries apply to aging in the real world. Research in Aging Cell provides insights into aging based on studies in dogs.

An international consortium of researchers has created the largest-ever database compiling records of brain activity during sleep and dream reports.

The termination of thousands of federal grants that fund clinical trials threatens to reverse substantial progress in understanding and treating the health challenges of marginalized populations, particularly children and adolescents who are already underrepresented in research.

Light-to-moderate alcohol consumption is associated with increases in blood pressure (BP) and stopping drinking – even drinking less – may lead to clinically meaningful BP reductions, according to a study published today in JACC, the flagship journal of the American College of Cardiology.

With ads everywhere for pro- or pre-biotic foods and supplements, most people are familiar with the gut microbiome-the trillions of bacteria, fungi, and viruses that colonize our digestive tract-and the idea that keeping our gut microbiome healthy improves our overall health.

An analysis in the Journal of the American Geriatrics Society reveals that older inpatients admitted to physicians who prescribe higher amounts of first-generation antihistamines face an elevated risk of delirium while in the hospital.

A study published in the British Journal of Health Psychology reveals the negative behavioral and psychological consequences of commercial fitness apps reported by users on social media.

A study in the Journal of Orthopaedic Research uses a noninvasive, nonradioactive imaging-based method to measure the structure and function of the Achilles tendon in professional ballet dancers.

Brain research can provide valuable information about children who may need extra support before they start struggling with reading in the classroom.

An international collaborative study has identified the E2F2 protein as a potential new therapeutic target to prevent metabolic fatty liver disease from progressing towards more serious conditions, such as cirrhosis or liver cancer.

Colorectal cancer is one of the most common tumors among people over the age of 50. Although it is known to develop from small lesions or polyps, its exact causes are unknown — only a few risk factors are known — and it is usually treated with surgery, chemotherapy and radiotherapy, or biological therapies.

A study published in the journal CABI One Health has revealed major inequalities in One Health research.

Tracking daily steps has become a staple exercise metric as smart devices keep count with ease. This physical activity stimulates bodily repair and maintenance, which is especially important as we age.

A new peer-reviewed study in the INFORMS journal Marketing Science finds that direct-to-consumer (DTC) advertising for prescription smoking-cessation drugs meaningfully reduces cigarette use. At the same time, the research found that advertising for over the counter (OTC) nicotine products does not reduce cigarette use.

Congenital heart block, sometimes referred to as cardiac neonatal lupus, is a rare but potentially life-threatening condition that affects babies born to mothers with specific autoantibodies - called anti-SSA/Ro antibodies - which can attack the fetal heart via its electrical conduction system, leading to a slower heart rate.