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Machine learning detects early rising behavioral changes in mouse models of Parkinson’s disease
Detecting early rising Parkinson's disease (PD) symptoms could improve treatment outcomes by enabling earlier treatment interventions.
Different expectations shape pain perception in distinct ways
Previous expectations can influence how much pain people eventually feel. These expectations can be shaped by external cues or by verbal information from clinicians about how treatments might relieve pain.
Research reveals financial toll of living with type 2 diabetes
In a first-of-its-kind study, researchers used a unique dataset to show that patients with type 2 diabetes have significantly worse financial outcomes than other patients.
Study finds significant associations between sleep traits and 172 diseases
A groundbreaking international study, recently published in Health Data Science, analyzed objective sleep data from 88,461 adults in the UK Biobank and found significant associations between sleep traits and 172 diseases.
Dental floss may offer a novel vaccine delivery method
Researchers have demonstrated a novel vaccine delivery method in an animal model, using dental floss to introduce vaccine via the tissue between the teeth and gums.
Understanding immune drift in biologic therapy for inflammatory skin diseases
Immune-inflammatory skin diseases (e.g., psoriasis, atopic dermatitis) involve dysregulation of CD4+ T-cell subsets (Th1/Th2/Th17/Treg) and cytokine networks (IL-17/IL-23/IL-4).
Restoring mitochondria enhances immune response against lung cancer
While chemotherapy remains a cornerstone of lung cancer treatment, it often weakens the immune system it relies on for long-term control.
TraMA offers breakthrough in measuring biological age
A new research paper was published in Aging (Aging-US) Volume 17, Issue 6, on June 13, 2025, titled "Development of a novel transcriptomic measure of aging: Transcriptomic Mortality-risk Age (TraMA)."
Metabolic rewiring turns immune cells into potent cancer fighters
Researchers have discovered a way to make the immune system's T cells significantly more effective at fighting cancer.
Vitamin D supplementation reduces liver inflammation and fibrosis largely through TXNIP
Chronic liver disease (CLD) is a major global health concern, affecting approximately 1.5 billion people. This life-threatening disease often progresses silently, eventually leading to worsened conditions like liver cirrhosis or liver cancer.
Marbling of fat inside muscles found to block healing and weaken strength
Consider the delicate web of fat in a Wagyu steak. The "marbling" that makes carnivore connoisseurs swoon is a visual heuristic for quality flavor.
Neutrophils emerge as key players in cancer progression and therapy
Neutrophils are the most abundant type of white blood cells, critical for immune defense and inflammation control.
Study: Formal education does not slow brain aging or cognitive decline
An international study published in the journal Nature Medicine casts doubt on the widespread belief that higher levels of formal education directly protect against cognitive decline and brain aging.
Columbia engineers create bioactive hydrogels using dairy-derived EVs
Researchers from Columbia Engineering have established a framework for the design of bioactive injectable hydrogels formulated with extracellular vesicles (EVs) for tissue engineering and regenerative medicine applications.
Largest genetic study confirms biological basis of stuttering
The largest genetic analysis of stuttering has demonstrated a clear genetic basis for the speech disorder, highlighting neurological pathways of risk.
Study reveals a strong link between early childhood adversities and depression in older Canadians
A new study of 3,500 Canadians aged 55 and older revealed a strong association between early childhood adversities and depression.
Study shows the importance of diet in influencing multimorbidity in aging populations
A healthy diet can slow down the accumulation of chronic diseases in older adults, while inflammatory diets accelerate it.
Australian scientists uncover new way to halt aggressive cancer growth
Australian researchers have discovered a promising new strategy to suppress the growth of aggressive and hard-to-treat cancers by targeting a specialized molecular process known as 'minor splicing'.
Promising new male birth control pill could be taken every three days
YCT-529, a novel non-hormonal male contraceptive, demonstrates safety and tolerability in early trials, offering a potential solution for male birth control.
Persistent intense grief linked to higher healthcare use and mortality
Grief after the loss of a loved one is a natural response – an inevitable part of living and loving. But in a minority of the bereaved, grief is so overwhelming that it can lead to physical and mental illnes, even if they don't necessarily qualify for a diagnosis with the mental health condition 'prolonged grief disorder'.