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Single injection of gene therapy at birth may offer lasting protection against HIV
A new study in Nature shows that delivering a single injection of gene therapy at birth may offer years-long protection against HIV, tapping into a critical window in early life that could reshape the fight against pediatric infections in high-risk regions.
Harnessing the power of gut bacteria to enhance cancer immunotherapy effectiveness
A comprehensive new review reveals both the promise and challenges of using fecal microbiota transplantation (FMT) to enhance cancer immunotherapy effectiveness.
Cancer immunotherapies linked to increased risk of liver cholestasis
A global study reveals that cutting-edge cancer immunotherapies, while lifesaving, carry a hidden risk: they may trigger cholestasis, a serious liver condition where bile flow stalls.
Myth of tongue swallowing delays life-saving CPR in collapsed athletes
Despite widespread public health efforts, the dangerous myth of "prevention of tongue swallowing" continues to persist during cardiopulmonary resuscitation (CPR).
New insights reveal how Candida albicans settle and persist in the gut
About 80% of people have the fungus Candida albicans in their gut. Although most of the time it persists unnoticed for years causing no health problems, C. albicans can turn into a dangerous microbe that causes serious diseases in many organs, including the urinary tract, lungs and brain.
Study identifies risk factors for second colorectal cancer in people with Lynch syndrome
A current study by the German Familial Colorectal Cancer Consortium is looking at the question of which people with Lynch syndrome are at an increased risk of developing a second colorectal cancer.
Intratumoral microbial metabolites shape the tumor microenvironment and impact immunotherapy
The tumor microenvironment (TME) represents a highly complex system that encompasses cellular components (such as cancer cells, stromal cells, and immune cells) and non-cellular components (such as blood vessels and signaling molecules).
Canadian scientists trap gut microbe fuel to improve blood sugar and liver health
A team of Canadian scientists has discovered a surprising new way to improve blood sugar levels and reduce liver damage: by trapping a little-known fuel made by gut bacteria before they wreak havoc on the body.
PD-1 helps guide immune memory cells to the skin early during infection
Weill Cornell Medicine researchers have discovered that PD-1—a molecule best known for putting the brakes on immune cells—also plays a critical role in helping T cells become long-term immune defenders in the skin.
Researchers classify how specific genetic mutations correspond to rare disorders
The NF-κB signaling pathway plays a pivotal role in how our bodies fight infection, heal, and regulate inflammation. At the heart of this pathway is the NEMO protein, encoded by the IKBKG gene.
Immune cells migrate from the gut to breast during pregnancy and lactation
Of the 3.6 million babies born in the United States each year, around 80 percent begin breastfeeding in their first month of life.
Study confirms post-pandemic rise in disorders of gut-brain interaction
A new international study confirmed a significant post-pandemic rise in disorders of gut-brain interaction, including irritable bowel syndrome (IBS) and functional dyspepsia, according to the paper published in Clinical Gastroenterology and Hepatology.
Analysis shows low pre-pregnancy glucose increases risk of preterm birth
An analysis of data from more than 4.7 million Chinese women showed that those who had low blood sugar levels prior to conception were more likely to have certain adverse pregnancy outcomes-such as their baby being born preterm or with low birth weight.
Antiviral treatment shows no benefit for early Alzheimer’s patients
The idea that herpes infections trigger or contribute to Alzheimer's disease has been gaining favor among some scientists, raising hope that herpes treatments could slow progression of Alzheimer's symptoms among patients.
New method uses exosome stiffness for lung cancer gene detection
The research team led by Senior Researchers Yoonhee Lee from the Division of Biomedical Technology and Gyogwon Koo from the Division of Intelligent Robot at DGIST (under President Kunwoo Lee) has developed a technology that distinguishes lung cancer gene mutations solely by measuring the "stiffness" of exosomes-tiny particles released from cancer cells in the bloodstream-using atomic force microscopy (AFM).
New genetic mutation linked to highly invasive streptococcus pyogenes infections
A group of researchers led by The University of Osaka have identified a novel genetic mutation in Streptococcus pyogenes, a common bacterium which causes strep throat, significantly associated with severe invasive infections.
Vaping recreates 1970s smoking uptake rates in UK teens
UK teens who currently vape are as likely to take up smoking as their peers in the 1970s, despite a substantial fall in the prevalence of teenage smoking over the past 50 years, suggests a long term intergenerational study published online in the journal Tobacco Control.
New study connects ultra-processed foods to lung cancer
A higher intake of ultra processed food (UPF) is linked to an increased risk of lung cancer, suggests research published online in the respiratory journal Thorax.
How cardiac rehab offers significant benefits for atrial fibrillation
Exercise-based cardiac rehabilitation lessens the severity, frequency, and recurrence of the most common form of irregular heart rhythm, atrial fibrillation, or AF for short, finds a pooled data analysis of the available research, published online in the British Journal of Sports Medicine.
Vanderbilt team explores functional β-cell enhancement for diabetes
If it has seemed like more people you know are developing diabetes, you are right. The diabetes epidemic is not called that for nothing: According to the American Diabetes Association, over 10 percent of the U.S. population-approximately 38.4 million people-had diabetes in 2021, and 1.2 million more people get diagnosed each year.