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The dental pulp is susceptible to microbial infection, which often results in inflammation, necrosis, and defects in the pulp-dentin complex. Traditional treatment strategies suffer from multiple limitations and do not promote neural regeneration.

Athletes are 2.5 times more likely than the general public to develop nail fungus, according to a study in the Journal of the American Academy of Dermatology.

Researchers at MIT and Stanford University have developed a new way to stimulate the immune system to attack tumor cells, using a strategy that could make cancer immunotherapy work for many more patients.

The menstrual cycle is a key physiological process in women: it impacts performance, neuromuscular control, metabolism, and immune response.

Lung infections like pneumonia are among the world's top killers - but diagnosing them is notoriously hard.

There is increasing evidence that gum disease is associated with increased risk of cardiovascular events, including heart attack, stroke, atrial fibrillation, heart failure and cardiometabolic health conditions. Effective prevention and treatment of gum disease, also called periodontal disease, could potentially decrease the burden of cardiovascular disease, according to a new scientific statement published today in the American Heart Association's flagship journal Circulation.

Parkinson's disease (PD) is an age-related, progressive, neurodegenerative condition, caused by loss of dopamine-producing neurons.

A new study identifies molecular factors that promote small vessel disease - and an active drug that can restore impaired vascular functions.

Researchers at the Technical University of Munich (TUM) and the Friedrich-Alexander-University Erlangen-Nuremberg (FAU) found that an increased fMRI signal is associated with reduced brain activity in around 40 percent of cases.

Research on SARS-CoV-2 in zoo tigers, lions, and hyenas shows rapid viral evolution and adaptation, offering insights into cross-species transmission dynamics.

Overcoming acquired treatment resistance is one of the major challenges in the fight against cancer. While combination therapies hold promise, their toxicity to healthy tissue remains a major hurdle. To anticipate these risks, researchers at the University of Geneva (UNIGE) have developed in vitro models of the kidneys, liver, and heart - three organs particularly sensitive to such therapies.

Every movement you make and every memory you form depends on precise communication between neurons. When that communication is disrupted, the brain must rapidly rebalance its internal signaling to keep circuits functioning properly.

Being more physically active, following a balanced diet, not smoking, and keeping body weight and blood pressure under control: the same habits that protect the heart also prove decisive after a cancer diagnosis.

New research from the University of St Andrews has discovered a direct causal effect between social isolation and a faster decline in later- life cognitive function. Pathological cognitive decline is most often driven by Alzheimer's and related dementias.

For much of the past century, Alzheimer's disease has been one of medicine's most daunting frontiers—biologically complex, devastating in impact, and difficult to diagnose early.

This review synthesizes preclinical evidence showing that cinnamon-derived compounds can modulate inflammation, oxidative stress, apoptosis, and angiogenesis through multiple cancer-related signaling pathways. While biologically plausible, the findings are largely limited to cell and animal models, underscoring the need for pharmacokinetic, safety, and clinical validation.

Indoor tanning is associated with markedly higher mutation burdens and cancer-driving genetic changes in melanocytes taken from normal-appearing skin, including areas usually protected from sunlight. These molecular alterations provide a biological explanation for the higher odds of melanoma and multiple primary tumors seen in heavy tanning bed users.

Neutrophils cause time-of-day–dependent collateral tissue damage after sterile injury through an intrinsic circadian program. Activating a CXCL12–CXCR4 checkpoint repositions neutrophils, limiting inflammatory injury without impairing antimicrobial defense.

This sibling-controlled East Asian study found that autistic individuals, their unaffected siblings, and typically developing controls differ in gut microbiota diversity and composition, with the clearest separation between autism and typical development. Specific taxa, particularly the butyrate-producing genus Anaerostipes, were modestly associated with social communication and internalising symptoms, supporting a gut–behaviour link without implying causality.

As people age, their bodies develop a dysfunctional immune system, which can leave older adults more susceptible to conditions like sepsis.