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Increasing our level of physical fitness leads to a bigger release of brain-boosting proteins following one session of exercise, a new study led by a UCL researcher has found.

Researchers at the University of California San Diego have identified new genetic variants associated with autism spectrum disorder (ASD) by using long-read whole genome sequencing (LR-WGS), an emerging approach that reads large sections of the genome at once, making it easier for scientists to find new genetic variants and understand how genetic variants affect the function of a gene.

University of Houston professor of psychology Arturo Hernandez is disputing a high-profile study published in the journal Nature Aging claiming that people who live in multilingual countries show healthier brain aging.

Although mental disorders have multifactorial causes, genetics can explain some of them, yet this field remains largely unexplored in terms of guiding diagnoses and treatments.

The prevalence of congenital heart disease points to the need for a better understanding of how it influences neurodevelopment. New in JNeurosci, Jung-Hoon Kim and Catherine Limperopoulos, from Children's National Hospital, led a study examining brain network disruptions that may be linked to congenital heart disease.

A community study of 280 adults in Cyprus examined whether tattoo presence and tattooed body surface area (tBSA) are associated with maladaptive personality traits. Tattooed individuals showed higher Disinhibition, while greater tattoo coverage was modestly linked to Antagonism and Disinhibition.

A single session of physical exercise can spawn a boost of neural activity in brain networks that underlie learning and memory, according to a new study led by the University of Iowa.

Researchers evaluated four deep learning models using over 112,000 negative screening mammograms from the UK NHS to determine how well artificial intelligence could predict future breast cancers missed during routine screening. The MIT-developed Mirai model performed best, identifying about 27.5% of interval cancers within the top 4% of women flagged as highest risk.

Immune checkpoint inhibitors targeting PD-1 and PD-L1 have revolutionized cancer therapy, delivering long-term survival benefits in several malignancies.

Patients with advanced cancer should be involved in decisions about their own treatment. Yet, patients, and relatives and nurses too, are often unsure how exactly this should take place, according to a new doctoral thesis from the University of Agder (UiA).

The cGAS-STING signaling pathway has emerged as a major focus in cancer immunotherapy because it stimulates interferon production and enhances antitumor immune responses.

Intracerebral hemorrhage (ICH) is the stroke subtype with the highest mortality and disability rates, and early hematoma evacuation is crucial for improving prognosis.

Malignant gliomas are among the deadliest brain cancers, with limited treatment options and poor survival.

Researchers analyzed 1,565 Japanese outpatients with type 2 diabetes and found that higher alcohol consumption was associated with lower intake of several micronutrients, particularly potassium, calcium, and vitamins A and C, in younger men. The study also linked alcohol intake to a savory dietary pattern rich in rice, meat, fish, and seasonings, highlighting age- and sex-specific nutritional risks.

Alcohol-associated liver disease (ALD) remains a leading cause of cirrhosis and liver-related mortality worldwide, with few effective therapies.

An analysis led by Mass General Brigham investigators found slower aging in older adults after two years of a daily multivitamin, with greater benefits for those who began the trial with accelerated biological age.

Women with certain cardiometabolic risk factors, including type 2 diabetes and high waist circumference, face a greater increase in risk for liver fibrosis than men with the same risk factors.

Rotator cuff tears are among the most common and debilitating musculoskeletal injuries, frequently causing chronic pain, reduced shoulder mobility, and a high risk of re-injury even after surgical repair.

At time when trust in health information is at unprecedented risk, the American Heart Association today welcomed new findings from the independent Annenberg Public Policy Center (APPC) at the University of Pennsylvania suggesting that Americans consider the Association the most trusted source of public health information after their personal physician.

The recreational drugs cannabis, cocaine and amphetamines significantly increase the risk of stroke – including among younger users – Cambridge researchers have concluded after analyzing data from more than 100 million people.