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This narrative review argues that the migraine brain is hypometabolic, with converging evidence of mitochondrial dysfunction, impaired glucose handling, neuroinflammation, microbiome shifts, and obesity-related pathways. It proposes ketogenic diets as a plausible preventive strategy that may reduce monthly migraine days and medication use, while emphasizing the need for larger, rigorous randomized trials and careful clinical oversight.

Research conducted on mice has identified that the rapid response of a specific type of defense cell is essential for controlling Oropouche virus infections and preventing serious neurological damage.

The characteristics of type 2 diabetes vary from patient to patient and it has been proposed that the condition is made up of four subtypes. Now, new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) shows that smoking increases the risk of the condition, regardless of subtype.

An AI algorithm based only on routine mammogram images plus age can predict a woman's risk of major cardiovascular disease as well as standard risk assessment methods, finds research published online in the journal Heart.

Physical sports have long been known to help with anxiety and mental health. But can augmented and virtual reality sports games improve psychological well-being and reduce loneliness? Researchers at Michigan State University's Department of Kinesiology say yes.

Although Black men die of prostate cancer at twice the rate of the rest of U.S. males, this fact often is not known or considered during appointments with their primary-care clinicians to discuss a common screening test.

The story of the princess and the pea evokes an image of a highly sensitive royal young woman so refined, she can sense a pea under a stack of mattresses.

A UCLA research team has found a new way to prompt the immune system to kill cells infected with cytomegalovirus (CMV), a life-threatening infection that is particularly deadly in immunocompromised people.

What compels someone to keep engaging in alcohol use, even if it damages their health, relationships and wellbeing? A new study from Scripps Research offers an important clue: a small midline brain region plays a key role in how animals learn to continue drinking to avoid the stress and misery of withdrawal.

Interventions to address firearm accessibility and related dangers should account not only for direct exposure to violence but also for complex psychosocial pathways through which firearms affect mental health across populations, according to a systematic scoping review published in the September/October issue of Harvard Review of Psychiatry, part of the Lippincott portfolio from Wolters Kluwer.

Complex biological systems are more than the sum of their parts – their properties emerge from the dynamic interaction of their components, such as molecules or cells.

Mark W. Feinberg, MD, cardiologist with the Mass General Brigham Heart and Vascular Institute and professor of medicine at Harvard Medical School, is the senior author of a paper published in the Journal of Clinical Investigation, "A smooth muscle cell lncRNA controls angiogenesis in chronic limb-threatening ischemia through miR-143-3p/HHIP signaling."

As Canada's health care system rapidly adopts digital technologies, a group of Canadian researchers is calling for a major overhaul of health professional education to ensure consistent, outcomes-based training in digital health and informatics competencies.

This study found that, in rats, acute nerve injuries that may recover can be distinguished from those that are unlikely to recover based on the response to intraoperative electrical nerve stimulation in the acute clinical setting.

Scientists from Duke-NUS Medical School, in collaboration with researchers in Nepal, have found that waning immunity to Japanese encephalitis virus (JEV) may increase the risk of more severe dengue disease in humans.

Stroke research aims to understand the brain's self-protective and repair mechanisms. Gaining detailed insight into these mechanisms is crucial as such knowledge could lead to newly developed medications and interventions which mimic or engage the brain's self-protective/repair mechanisms, leading to innovative stroke therapies.

Neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's disease are characterized by the progressive loss of neurons.

Muscular Dystrophy UK, a charity working on behalf of 110,000 children and adults living with more than 60 muscle-wasting conditions, has awarded £140,944 in funding to Dr. Rebecca Jones at Aston University for a project to understand the cause of a condition called inclusion body myopathy.

Most bacteria cannot be cultured in the lab-and that's been bad news for medicine. Many of our frontline antibiotics originated from microbes, yet as antibiotic resistance spreads and drug pipelines run dry, the soil beneath our feet has a vast hidden reservoir of untapped lifesaving compounds.

Flavored drinks without sugar can be perceived as sweet - and now researchers know why. A new study from Karolinska Institutet in Sweden, published in the journal Nature Communications, reveals that the brain interprets certain aromas as taste.