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Study links severe COVID to higher TB risk, and vaccination appears to blunt the link
A nationwide Chilean cohort study of more than 3.6 million adults found that severe COVID-19 requiring hospitalization was associated with more than an eightfold higher hazard of incident tuberculosis within one year. The association was strongest in the first six months and among unvaccinated individuals, although absolute TB incidence remained low.
Melatonin may safely reduce chronic musculoskeletal pain, study finds
A sleep supplement widely used to treat insomnia could help reduce reliance on some of the most common and potentially harmful pain medications, new research from the University of Sydney suggests.
Blood biomarker may predict Alzheimer's progression differently in men
A blood test does not lie, exactly. It reports a number. The question raised by a new mini-review in Brain Medicine, which gathers and weighs a decade of scattered findings, is whether clinicians have been reading the same number in two different ways without realizing it.
New HIV vaccine shows unprecedented success in primate studies
A groundbreaking new HIV vaccine has shown unprecedented success in primates-and data published in Nature suggest the vaccine has the potential to protect humans from developing HIV infection and AIDS.
Botanical prebiotics may steer skin microbes toward healthier balance
Researchers tested plant-derived prebiotic candidates against selected skin-associated bacteria and found that garlic, flaxseed, and mango ginger extracts inhibited S. aureus or acne-associated C. acnes in vitro. Onion and guduchi extracts modestly promoted S. epidermidis, suggesting a microbiome-targeted skincare route that now needs validation in skin models and human studies.
Monoclonal antibody shows promise for treating acute respiratory distress syndrome
Doctors have few options for patients who develop a life-threatening lung condition called acute respiratory distress syndrome, or ARDS.
Study links DNA methylation to aggressive prostate cancer behavior
The prostate is the single organ most frequently afflicted by cancer in men. Prostate cancer affects approximately 4 million American men, with another 330,000 men expected to be diagnosed with the condition this year alone.
Review highlights strong safety and effectiveness of mRNA vaccines
A comprehensive new review published in The Lancet affirms that currently approved mRNA vaccines are safe and highly effective at preventing infectious diseases, including COVID-19.
Vitamins A and D may support healthier lungs in asthma patients
Higher levels of circulating vitamin A are linked to better lung function in children and adults with asthma, while vitamin D shows similar benefits in adults, including slower biological ageing, finds the first study of its kind, published online in the respiratory journal Thorax.
High-dose intravenous vitamin C may improve trauma patient survival outcomes
High doses of intravenous (IV) vitamin C may lower the risks of death and sepsis in trauma patients, as well as shortening hospital stay, suggests a review of the available evidence published online in the journal BMJ Military Health.
Global review reveals persistent discrimination against people with psychosis
People with psychosis continue to face abuse, discrimination and early death, despite global reform efforts to protect their human rights, according to La Trobe University researchers.
Blood protein clocks flag higher risks of death and chronic disease
Proteomic age clocks applied to two European cohorts linked faster biological aging with smoking, alcohol use, physical inactivity, all-cause mortality, cardiovascular disease, dementia, and several cancers. The Global proteomic clock predicted mortality as well as established lifestyle risk factors, while organ-specific clocks showed stronger links with related cancers of the kidney, lung, and stomach.
Researchers use AI to predict rare cancer immunotherapy responses
Researchers from The University of Texas MD Anderson Cancer Center demonstrated that an artificial intelligence (AI)-based analysis of tumor biopsies can predict responses to immunotherapy in a study of patients with rare cancers, published in the Journal for ImmunoTherapy of Cancer.
Mice move strategically to gather hidden visual information in VR
Animals don't experience the world passively. A hawk tilts its head to track prey. A person leans forward to read a sign. Scientists call this "active sensing": moving the body to gather better information.
Experts reframe steatotic liver disease as a dynamic continuum
The classification of steatotic liver disease (SLD) is undergoing a major conceptual transformation. In a recent article published in eGastroenterology, Dr. Chen, Dr. Horn, and Prof. Tacke from Charité - Universitätsmedizin Berlin argue that metabolic dysfunction-associated steatotic liver disease (MASLD), metabolic dysfunction and alcohol-associated liver disease (MetALD), and alcohol-associated liver disease (ALD) should not be regarded as rigid diagnostic categories, but rather as interconnected and evolving disease trajectories.
Florida study finds elevated traffic fatality rates during spring break
On any given U.S. holiday, traffic crashes claim more than 500 lives. But according to a new study published in Risk Analysis, the real danger lurks early in the annual calendar.
New structural insights overturn old assumptions about malaria entry
For nearly half a century, scientists have known that malaria parasites force their way into human red blood cells through a ring-shaped structure called the moving junction.
SickKids study uncovers cell recovery mechanisms linked to stomach cancer
Few areas of the body face more daily stress and potential damage than the stomach, which must manage everything we swallow.
Altering gut microbes could improve immunotherapy responses in liver cancer
Immune checkpoint blockade (ICB) has reshaped the treatment landscape for advanced hepatocellular carcinoma (HCC), offering new hope where few options existed.
Obesity drives distinct molecular pathway toward invasive breast cancer
A novel study has found that obesity is associated with a distinct molecular program driving the transition from early-stage, premalignant breast lesions to invasive breast cancer.




