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Australian scientists uncover key genetic drivers behind long COVID

Rss Feed - Mon, 12/15/2025 - 20:24
Australian scientists have identified the key genetic drivers behind long COVID, revealing why some people continue to experience debilitating symptoms long after their initial infection.

Understanding how the immune system protects against fungal pathogenicity

Rss Feed - Mon, 12/15/2025 - 09:22
The yeast Candida albicans colonizes mucosal surfaces and is usually harmless. However, under certain conditions it can cause dangerous infections.

How brain cells manage long distance genetic instructions

Rss Feed - Mon, 12/15/2025 - 08:22
Scientists found that messenger RNA (mRNA) molecules that carry genetic instructions to the far reaches of neurons in the brain tend to cluster together mostly because they are abundant, not because they move in coordinated groups.

Single-pill combination medications may simplify treatment for adults with high blood pressure

Rss Feed - Mon, 12/15/2025 - 07:54
Taking one pill that combines two or more blood pressure medications may help adults with high blood pressure (also known as hypertension) lower their blood pressure level faster and more effectively than taking multiple medications separately, and it may also reduce the risk of heart attack and stroke, according to a new scientific statement published today in the American Heart Association's journal Hypertension.

Two compounds sourced from cannabis show promising anti-cancer effects

Rss Feed - Mon, 12/15/2025 - 07:05
In the future, scientists could use drugs made from cannabis to fight ovarian cancer. A team of scientists testing the effects of two chemical compounds sourced from cannabis on ovarian cancer cells have found that both show promising anti-cancer effects.

Gut bacteria mimicry can accelerate the progression of multiple sclerosis

Rss Feed - Mon, 12/15/2025 - 06:44
If gut bacteria are too similar to the protective layer of nerves, they can misdirect the immune system and cause it to attack its own nervous system.

Global study finds stark differences in survival among children with cancer

Rss Feed - Mon, 12/15/2025 - 06:34
Every year, more than 200,000 children under the age of 15 are diagnosed with cancer worldwide, and nearly 75,000 die from the disease.

Study identifies a distinctive, measurable pattern of brain activity in children with ADHD

Rss Feed - Mon, 12/15/2025 - 06:30
A new study suggests that children with ADHD may exhibit a distinctive, measurable pattern of brain activity that could reflect differences in neural efficiency.

Study: 1 in 4 children with major trauma do not receive care in pediatric trauma centers

Rss Feed - Mon, 12/15/2025 - 06:03
New research shows that 1 in 4 children with major traumatic injury do not receive care in a pediatric trauma centre, where outcomes are generally better than in adult centers.

A new trial investigates whether the MIND diet can be scaled for obesity management

Rss Feed - Sun, 12/14/2025 - 20:57
This study protocol outlines a 12-week randomized trial testing whether a MIND diet intervention is feasible, acceptable, and sustainable for adults with obesity in Sweden. It will generate preliminary evidence on adherence, mental well-being, and gut microbiota changes to inform larger efficacy trials.

E-cigarette use is linked to higher heart attack risk, especially in former smokers

Rss Feed - Sun, 12/14/2025 - 20:26
his systematic review and meta-analysis examined whether electronic cigarette use is associated with myocardial infarction and stroke, synthesizing evidence from 12 observational studies. The analysis found higher odds of myocardial infarction among e-cigarette users, particularly former smokers, while no significant associations were observed among exclusive never-smokers.

Metabolic syndrome affects nearly four in ten US adults as rates climb in older and Black populations

Rss Feed - Sun, 12/14/2025 - 19:47
A large NHANES analysis found that nearly four in ten US adults met criteria for metabolic syndrome between 2013 and 2023, with no statistically significant change in overall prevalence. However, prevalence rose significantly among adults aged 60 years and older and among non-Hispanic Black individuals, alongside a significant non-linear increase in hypertriglyceridemia.

Swapping high-carb snacks for tree nuts cuts food cravings in young adults at metabolic risk

Rss Feed - Sun, 12/14/2025 - 19:28
Daily replacement of typical high-carbohydrate snacks with mixed tree nuts for 16 weeks reduced cravings for sweets and fast foods in young adults with early metabolic syndrome risk. This dietary swap improved overall diet quality, measured by the Healthy Eating Index, without increasing body weight or altering short-term glycaemic markers.

Researchers develop powerful tools for microbiome research advancement

Rss Feed - Sat, 12/13/2025 - 02:38
The microscopic organisms that fill our bodies, soils, oceans and atmosphere play essential roles in human health and the planet's ecosystems. Yet even with modern DNA sequencing, figuring out what these microbes are and how they are related to one another remains extremely difficult.

Hypertrophic chondrocytes play a crucial role in bone growth and repair

Rss Feed - Sat, 12/13/2025 - 02:26
Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving the growth of cartilaginous cells or chondrocytes, their transformation into bone-building cells or osteoblasts, and the formation of new blood vessels to supply the newly formed bone tissue.

Engineering muscle stem cells for sustainable cultured meat production

Rss Feed - Sat, 12/13/2025 - 02:13
The production of cultured meat depends on the isolation, expansion, and differentiation of animal stem cells into edible tissues. Muscle stem cells, or satellite cells, are central to this process due to their ability to regenerate and form muscle fibers.

Cryo-EM reveals NPFFR1 activation and guides novel ligand design

Rss Feed - Sat, 12/13/2025 - 01:57
This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of neuropeptide FF receptor 1 (NPFFR1)-a Gi/o-coupled receptor that responds to endogenous RF-amide peptides (RFRP-3 from pro-NPFFB, NPFF from pro-NPFFA) and regulates physiological processes like opioid function, pain, and energy homeostasis.

Single-cell RNA-seq reveals FBLN7's role in adipose tissue fibrosis

Rss Feed - Sat, 12/13/2025 - 01:50
Fibrosis, resulting from excess extracellular matrix (ECM) deposition, is a feature of adipose tissue (AT) dysfunction and obesity-related insulin resistance.

Lowering blood sugar reduces heart risk in prediabetes

Rss Feed - Fri, 12/12/2025 - 21:45
Lowering blood sugar levels halves the likelihood of serious heart problems in people with prediabetes.

Genetic differences in surfactant proteins influence retinopathy of prematurity risk

Rss Feed - Fri, 12/12/2025 - 21:40
A new study from the University of Oklahoma suggests that small genetic differences in two proteins – previously known for their role in premature infants' lungs – may also influence how their eyes develop, potentially affecting the risk of retinopathy of prematurity (ROP).

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