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Researchers at Niigata University have conducted the first comprehensive reappraisal in nearly 30 years of the risk of Alzheimer's disease (AD) associated with APOE-e4 homozygosity (e4*4) in the Japanese population.

Dental enamel is the hardest substance in the human body, protecting teeth from wear, temperature changes, and decay. However, enamel cannot regenerate once damaged. Inherited disorders, such as amelogenesis imperfecta, disrupt enamel formation during development, leaving affected individuals with fragile, discolored, and decay-prone teeth.

French children and adults widely consumed foods likely to contain live microbes, mainly yogurt, unpasteurised cheese, fruits, and vegetables. Higher intake was associated with more nutrient-rich diets and better diet quality scores, but the cross-sectional study cannot prove health benefits.

A new study used pathway-level blood metabolomics to identify lifestyle-associated metabolic patterns linked to physical, cognitive, and daily functional performance across CN, MCI, and AD. The findings suggest that diet- and activity-linked pathway signals span energy, amino acid, lipid, inflammatory, oxidative stress, and microbiome-related metabolism, but require independent and longitudinal validation.

The first randomized, controlled trial for a common childhood eating disorder has shown how therapists and parents can help those struggling with the condition, known as avoidant restrictive food intake disorder, or ARFID.

Antibiotic resistance is one of the most urgent threats to global health, linked to an estimated 4.7 million deaths worldwide in 2019 alone.

A new award from the National Institute on Drug Abuse will advance a smartphone-based treatment aimed at helping pregnant individuals quit smoking.

Scientists at the University of Oklahoma have identified a previously unrecognized immune system pathway that helps explain how cigarette smoking increases the risk of cardiovascular disease.

Exposure to extreme heat and cold is associated with an increased risk of emergency department (ED) visits among people living with dementia, according to preliminary research presented today at the European Academy of Neurology (EAN) Congress 2026.

Is vaping bad for my health? As people who use e-cigarettes and their loved ones pose questions like this, growing scientific evidence shows that the answer is yes.

Researchers at the University of Colorado Anschutz have found that healthy yet sedentary individuals show a significant, coordinated drop in muscle mitochondrial function that may precede the development of major diseases like cancer, diabetes, and Alzheimer's.

As teenagers increasingly turn to artificial intelligence chatbots for advice about friendships, family conflicts and romantic ties, researchers are raising concerns that the technology could disturb how young people learn to navigate human relationships.

New research led by the University of East Anglia (UEA) suggests even modest, short-term changes in weather can have a measurable impact on NHS mental health service demand across England.

A new study found that later birth cohorts showed greater biological aging, measured by systemic age-gap clocks. Greater biological aging was associated with higher early-onset solid cancer risk, especially lung, gastrointestinal, and uterine cancers.

Low back pain affects over 600 million people and is the single leading cause of disability worldwide.

The drugs that keep rheumatoid arthritis in check may one day help people stop drinking. A new Scripps Research study shows that an anti-inflammatory molecule, already approved by the U.S. Food and Drug Administration to treat autoimmune diseases, reduces excessive alcohol consumption in alcohol-dependent female mice.

In the U.S., Hispanic/Latino populations are disproportionately at risk for eye diseases like glaucoma and diabetic retinopathy, or vision loss tied to diabetes.

Scientists usually use animal models when studying Parkinson's disease because these models mimic the disease well.

An experimental drug has been shown to alleviate symptoms of Huntington's disease and extend lifespan in mouse models. Further studies are required to determine whether these results may also apply to humans.