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Children from deprived areas face worse outcomes in intensive care

Rss Feed - Fri, 07/11/2025 - 00:31
Children from ethnic minority backgrounds and those living in areas with higher levels of child poverty were more likely to die in intensive care than White children and those from the least deprived areas.

Frequent gabapentin use linked to higher dementia and cognitive impairment risk

Rss Feed - Thu, 07/10/2025 - 23:47
Receiving six or more prescriptions of the drug gabapentin for low back pain is associated with significantly increased risks of developing dementia and mild cognitive impairment (MCI)--29% and 85%, respectively-finds a large medical records study published online in the journal Regional Anesthesia & Pain Medicine.

Early-onset diabetes rates soar among young adults in Sweden

Rss Feed - Thu, 07/10/2025 - 22:45
Early-onset type 2 diabetes nearly doubled in Sweden between 2006 and 2021, with the sharpest increases among young adults, ethnic minorities, and those with lower education. Projections show early-onset T2D could triple by 2050, posing a major public health challenge.

Distressed births linked to mental and physical problems later in life

Rss Feed - Thu, 07/10/2025 - 22:39
A research study crafted by two University of Miami Patti and Allan Herbert Business School professors establishes a strong correlation between distressed births and experiencing mental and physical problems later in life.

TMP-SMX in early pregnancy increases risk of birth defects, new study shows

Rss Feed - Thu, 07/10/2025 - 22:18
A large US cohort study found that using trimethoprim-sulfamethoxazole (TMP-SMX) for UTI in the first trimester of pregnancy was associated with a higher risk of congenital malformations compared to β-lactam antibiotics. No increased risk was seen with nitrofurantoin or fluoroquinolones.

Mitochondria and peroxisomes work together to defend against cell damage

Rss Feed - Thu, 07/10/2025 - 22:10
An international team led by researchers at The Hospital for Sick Children (SickKids), Princess Margaret Cancer Centre, Dalhousie University, the University of Exeter (UK) and the Medical University of Vienna (Austria) has uncovered a surprising way compartments within cells work together to defend themselves against oxidative stress, a finding that could shift how we understand age-associated conditions such as diabetes and neurodegenerative diseases.

UCLA study may help explain why certain liver tumors return after thermal ablation

Rss Feed - Thu, 07/10/2025 - 22:00
A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center may help explain why certain liver tumors return quickly after thermal ablation, a widely used minimally-invasive, image-guided technique that kills cancer cells by applying intense heat through a needle-like probe.

Early access to green spaces can boost children's cognitive capacities

Rss Feed - Thu, 07/10/2025 - 21:55
Access to nature promotes physical and mental health, and it is vital for children's social and emotional development.

Targeting SRSF7 offers potential therapy for pulmonary fibrosis

Rss Feed - Thu, 07/10/2025 - 21:41
This new article publication from Acta Pharmaceutica Sinica B, discusses how SRSF7 promotes pulmonary fibrosis through regulating PKM alternative splicing in lung fibroblasts.

How a simple blood test can forecast future health risks

Rss Feed - Thu, 07/10/2025 - 21:35
Plasma proteomics reveals that the biological ages of key organs, especially the brain and immune system, strongly predict the risk of future disease and early death. These organ-specific “clocks” provide a new tool for identifying those at highest risk and personalizing preventive care.

Weight loss wipes out senescent fat cells but leaves immune scars, study finds

Rss Feed - Thu, 07/10/2025 - 21:11
Researchers have mapped human fat tissue at single-cell resolution, uncovering how obesity alters cellular stress, inflammation, and tissue structure. Weight loss reverses much of this damage, especially senescence in fat and vascular cells, but leaves some immune dysfunction behind.

Does pomegranate seed oil really help your heart? New research weighs the evidence

Rss Feed - Thu, 07/10/2025 - 20:39
This review explores the potential of punicic acid in pomegranate seed oil as a nutraceutical for cardiovascular health. While preclinical evidence is promising, robust human trials are needed to confirm its benefits.

How hydrogels are shaping the future of targeted cancer drug delivery

Rss Feed - Thu, 07/10/2025 - 20:09
A large-scale bibliometric analysis maps global research on hydrogels as next-generation drug delivery systems for cancer therapy. The study highlights emerging trends, key contributors, and future directions to advance precision medicine in oncology.

Pasta gets a protein upgrade with eco-friendly cricket flour

Rss Feed - Thu, 07/10/2025 - 19:41
Cricket flour is rich in protein, essential minerals, and healthy fats, offering a sustainable boost to the nutritional quality of wheat pasta. Adding just 10% cricket flour to pasta significantly improves nutrient content and meets daily amino acid requirements while ensuring food safety.

Finland maintains world-leading neonatal outcomes despite falling birth rates

Rss Feed - Thu, 07/10/2025 - 15:23
Finland remains a world-leader in neonatal care, despite the country's falling birth rate and, consequently, a decline in hospital delivery volumes, according to three recent studies from the University of Eastern Finland.

Understanding resistance to EGFR targeted therapies in head and neck cancers and breast cancer

Rss Feed - Thu, 07/10/2025 - 15:17
A new review was published in Volume 16 of Oncotarget on June 25, 2025, titled "Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms."

Psychological stress drives ovarian tumor metastasis through NR3C1 and NUPR1

Rss Feed - Thu, 07/10/2025 - 14:31
This new article publication from Acta Pharmaceutica Sinica B, discusses how a psychological stress-activated NR3C1/NUPR1 axis promotes ovarian tumor metastasis.

New insights into neural replay and memory formation from flying bats

Rss Feed - Thu, 07/10/2025 - 14:26
Every day, our brain takes countless fleeting experiences - from walks on the beach to presentations at work - and transforms them into long-term memories.

Scientists discover pathway linking physical pain to emotional suffering

Rss Feed - Thu, 07/10/2025 - 14:18
Pain isn't just a physical sensation-it also carries emotional weight. That distress, anguish, and anxiety can turn a fleeting injury into long-term suffering.

Breakthrough research uncovers multiple autism subtypes with unique traits

Rss Feed - Thu, 07/10/2025 - 13:49
Researchers at Princeton University and the Simons Foundation have identified four clinically and biologically distinct subtypes of autism, marking a transformative step in understanding the condition's genetic underpinnings and potential for personalized care.

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