Feed aggregator

Reproductive effort affects lifespan under harsh conditions

Rss Feed - Fri, 11/07/2025 - 20:49
Scientific theory predicts that having more offspring leads to a shorter life span, including in humans. However, despite some hundred years of research, there is no unequivocal evidence for this link.

New molecule offers a promising avenue to treat triple-negative breast cancer

Rss Feed - Fri, 11/07/2025 - 20:42
A new molecule developed by researchers at Oregon Health & Science University offers a promising avenue to treat intractable cases of triple-negative breast cancer - a form of cancer that is notoriously aggressive and lacks effective treatments.

Unregulated nicotine pouches gaining popularity among young people in Scotland

Rss Feed - Fri, 11/07/2025 - 20:34
Young people in Scotland are experimenting with nicotine pouches and reporting adverse effects such as sickness and fainting, according to new research from the Scottish Centre for Social Research (ScotCen) published today in the journal Addiction.

Weaning hospitalized patients from dialysis may restore kidney function

Rss Feed - Fri, 11/07/2025 - 20:29
Weaning patients with acute kidney injury (AKI) from dialysis while they are still hospitalized may save them from remaining on the treatment for the rest of their lives, according to a new study led by UC San Francisco.

Simple family-based tool enhances early detection of postoperative delirium

Rss Feed - Fri, 11/07/2025 - 20:18
A new study published in the Journal of Clinical Anesthesia shows that family members and caregivers can play a critical role in detecting delirium after surgery using a simple tool known as the Family Confusion Assessment Method.

New NIH grants fuel research in oral cancer treatment and pain relief

Rss Feed - Fri, 11/07/2025 - 20:11
Researchers at the School of Dentistry at UT Health San Antonio, the academic health center of The University of Texas at San Antonio, have been awarded three multi-year grants totaling $6 million from the National Institutes of Health to address treatment and pain management for oral cancer.

New radioimmunotherapy approach shows potential to cure HER2-positive breast cancer

Rss Feed - Fri, 11/07/2025 - 20:07
A new radioimmunotherapy approach has the potential to cure human epidermal growth factor receptor 2 (HER2)-positive breast cancer, according to new research published in the November issue of The Journal of Nuclear Medicine.

Harnessing nanotechnology to deliver CBD to the brain for neuropathic pain relief

Rss Feed - Fri, 11/07/2025 - 20:00
Reaching for CBD-infused lotion or oil may seem like a low-risk way to find pain relief, but little is actually known about the impact that CBD has on the nervous system.

Rising premature deaths prevent many Americans from reaching the age of Medicare eligibility

Rss Feed - Fri, 11/07/2025 - 19:54
For 60 years, Medicare has served as a social safety net. Workers pay into the system over their lifetimes with the expectation that they will be able to access affordable health care when they turn 65.

Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms

Rss Feed - Fri, 11/07/2025 - 19:45
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of rare disease, and present case studies of affected patients through a collaboration with Boston Children's Hospital.

Rockefeller scientists engineer next-generation antibody to replace IVIG therapy

Rss Feed - Fri, 11/07/2025 - 19:39
Intravenous immunoglobulin (IVIG) therapy involves infusing patients with naturally occurring IgG antibodies to treat autoimmune conditions.

New insights reveal how TCF and LEF proteins control Wnt signaling and disease progression

Rss Feed - Fri, 11/07/2025 - 19:33
Researchers have unveiled the intricate molecular mechanisms governing TCF/LEF-mediated transcription in the canonical Wnt pathway, identifying these proteins as promising therapeutic targets for cancer and fibrotic diseases.

Study reveals structural and cellular clues behind cancer-linked GnT-V enzyme selectivity

Rss Feed - Fri, 11/07/2025 - 19:28
Glycans are important complex carbohydrates found on cell surfaces that serve crucial roles in cell-to-cell communication, structure, and protection.

New method promises to alleviate the symptoms of multiple sclerosis

Rss Feed - Fri, 11/07/2025 - 19:22
About 1 million people in the U.S. live with multiple sclerosis, a chronic autoimmune disease that inflames the nervous system and scrambles communication between the brain and body.

Scientists uncover mechanism driving efficient protein deacetylation by Sir2 enzyme

Rss Feed - Fri, 11/07/2025 - 19:16
Sir2, an enzyme belonging to sirtuins, has been effectively involved in the deacetylation of proteins. A tandem allosteric effect of reactant and product is responsible for the efficient deacetylation cycle of the Sir2 enzyme, reveal researchers from Science Tokyo.

Exploring endogenous retroviruses as hidden drivers of alcohol use disorder

Rss Feed - Fri, 11/07/2025 - 19:07
Alcohol use disorder (AUD), characterized by uncontrollable alcohol consumption due to physical and psychological dependence, affects approximately 14.1 million people in the U.S.

Single-cell analysis reveals HPV-induced keratinocyte heterogeneity in cervical cancer

Rss Feed - Fri, 11/07/2025 - 11:48
Cervical squamous cell carcinoma (CESC), the most prevalent subtype of cervical cancer, remains a major global health burden driven primarily by persistent high-risk HPV infection and genetic susceptibility.

Study reveals trends and future projections of cancer mortality in China

Rss Feed - Fri, 11/07/2025 - 11:31
Cancer remains the second leading cause of death in China, accounting for nearly one-quarter of all deaths nationwide. Rapid socioeconomic change, environmental exposure, and an aging population have intensified the burden of cancer across the country.

Comprehensive kinase atlas reveals new insights into cell signaling and disease

Rss Feed - Fri, 11/07/2025 - 08:16
The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's "tail" called phosphorylation patterns.

Diabetes drug blunts exercise-induced health improvements

Rss Feed - Fri, 11/07/2025 - 08:08
A widely prescribed diabetes drug may be sabotaging one of the most trusted strategies for preventing the disease: exercise.

Pages