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For the many patients with depression who haven't found relief through medication, transcranial magnetic stimulation (TMS) - a noninvasive therapy that uses magnetic pulses to stimulate specific areas of the brain - has become an increasingly important treatment option.

Subtle changes in how blood flows through the brain and how brain tissue uses oxygen may be closely linked to Alzheimer's disease risk, according to new research from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC.

A research team in Kumamoto University has discovered that a natural compound found in pomegranate leaves and branches can directly break down harmful protein aggregates linked to transthyretin (TTR) amyloidosis, a progressive and potentially life-threatening disease affecting the nerves and heart.

Researchers analysed highly viewed YouTube videos on nausea and vomiting in pregnancy and found most recommendations lacked strong scientific evidence. Some advice appeared potentially unsafe, highlighting the need for clearer evidence-based guidance for pregnant women online.

Daily diary data from healthcare workers and community adults during COVID lockdowns showed that people reported less loneliness on days when they experienced greater awe. This association was partly explained by increased feelings of connectedness to nature, although the observational design prevents causal conclusions.

Higher intake of ultra-processed foods in adults with obesity was associated with disordered eating symptoms, poorer diet quality, and lower protein intake. The cross-sectional findings suggest dietary processing level may influence eating behaviour patterns relevant to obesity management, though causality cannot be inferred.

A cross-sectional study of pregnant adolescents found that skipping meals, screen distraction during eating, and low dairy intake were associated with higher depressive symptom prevalence. Overall dietary diversity showed no significant relationship, and causality could not be established.

Engineers at the University of Pennsylvania and Rice University have refined a technology for editing individual genetic "base pairs" to a new level of precision, opening the door to safer, more reliable therapies for a wide range of genetic diseases, and to potential treatments for some cystic fibrosis patients that may yield better outcomes than existing therapies.

For more than six decades, biomarker-based newborn screening has played a pivotal role in reducing infant mortality and long-term disability by enabling early detection of metabolic and endocrine disorders.

In a study of adults with cancer, those who developed a mental health condition within the first year after their cancer diagnosis had a higher likelihood of dying over the next few years.

Coronary artery disease (CAD) is the most common cause of death globally. In CAD, plaques composed of cholesterol, fats, calcium and other compounds accumulate and create obstructions in the coronary vessels that supply blood to the heart.

SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache and depression.

An analysis co-led by Josefa A. Antón Ruiz, a researcher from the Department of Health Psychology at the University of Alicante (UA), reveals that 43.5% of healthcare professionals experienced clinically significant symptoms of insomnia during and after the COVID-19 pandemic.

Loughborough University and Science in Sport (SiS) have announced a renewed three-year partnership, strengthening the organizations' long-standing collaboration across elite sport and performance nutrition.

New findings reveal bilingual mother-child interactions enhance neural synchrony, highlighting the role of play over language in early cognitive development.

The use of antipsychotic medications for purposes other than those officially approved is common among older adults in Finland.

Antimicrobial resistance poses a growing global health crisis, with few new antibiotics in development.

Chronic hypoxia improves glucose tolerance in mice through insulin-independent mechanisms, with red blood cells acting as a major systemic glucose sink. Increased erythrocyte production and altered glycolytic flux help reduce circulating glucose while supporting oxygen delivery to tissues.

This systematic review in Nutrients evaluates human studies investigating whether polyphenol-rich berry consumption can modulate obesity-related metabolic dysfunction and support cognitive performance, particularly in individuals at risk of mild cognitive impairment. Evidence suggests modest memory benefits and possible metabolic improvements, although biomarker findings and long-term clinical relevance remain uncertain.

Emerging evidence suggests reduced plasma PPP2R5C levels may serve as an early indicator of Alzheimer’s disease before overt clinical symptoms appear. The protein appears linked to tau regulation, autophagy pathways, and cognitive decline, supporting its potential diagnostic relevance.