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Potassium-competitive acid blockers match proton pump inhibitors for preventing bleeding after PCI
Announcing a new article publication for Cardiovascular Innovations and Applications journal. Dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) increases the risk of upper gastrointestinal bleeding (UGIB).
Wake-activated brain circuits reveal what drives the urge to sleep
Researchers identified wake-activated neurons in the median raphe and anterior medial preoptic area that track sleep pressure and help regulate when and how deeply mice sleep. Manipulating these circuits altered NREM sleep, sleep-pressure accumulation, and rebound sleep, revealing key neural mechanisms underlying mammalian sleep homeostasis.
Capillaries drive new collateral artery formation after heart blockage
New research in mice challenges a long-standing view of how the heart builds backup blood vessels after a coronary artery blockage, showing that new collateral arteries arise primarily from capillaries rather than existing arteries.
Cross-generational friendships reshape brain synchrony in unexpected ways
The closer two people grow, the more alike their brains work– or so the assumption goes. Two ETH Zurich studies challenge this idea by examining the brain activity of younger and older adults who drew together over several weeks.
Digital program reduces anxiety and depression in adults with chronic medical conditions
A digital program combining guided movement, breathing and meditation exercises, and coping-skills training reduced anxiety and depression symptoms in adults with chronic medical conditions, according to a new study published August 20th in the open access journal PLOS Medicine by Puneeta Tandon of the University of Alberta, Canada, and colleagues.
Glioma microenvironment emerges as key target for future therapies
The prognosis for glioma patients remains extremely poor despite aggressive multimodal standard therapy: maximal safe resection, radiotherapy, and temozolomide chemotherapy, with median survival rarely exceeding 15 to 18 months.
Sprinters and non-athletes had similar gut diversity, but one key difference emerged
College sprint athletes showed a distinct gut microbial community structure, including higher abundance of Segatella copri and Bifidobacterium adolescentis, compared with non-athletic students. Their microbiomes also showed predicted enrichment of carbohydrate and amino acid metabolism pathways, while exploratory analyses linked several dietary factors with the signature bacteria.
Psilocybin may make the brain more organized than scientists expected
In 62 adults, researchers combined fMRI, EEG and machine learning to examine how psilocybin reshapes brain activity during rest, meditation, music and movie viewing. They found that context-sensitive neural organization tracked the intensity and quality of psychedelic experiences and was associated with next-day mindset change.
What happens to your diet when you get better at cooking?
Cooking-skills interventions were associated with healthier dietary behaviors in healthy adults, including greater fruit and vegetable intake, improved diet quality, and greater cooking confidence. However, the certainty of evidence was low to very low, and too little evidence was available to determine whether cooking skills affect nutritional status.
Federal and industry sponsors play complementary roles in cancer clinical trials
A comparative study of the cancer clinical trial portfolios supported by federal funding versus industry funding reveals they have distinct, interdependent roles in cancer research.
AI predicts vaccine response based on pre-existing antibody patterns
Vaccines protect most people from serious illness, but the strength of that protection can vary considerably from one person to another. A new study led by Arizona State University helps us understand why.
Study shows how prostate tumors rewire metabolism to resist therapy
Prostate tumors can rewire amino acid metabolism to override the normal brakes on cholesterol production, a process that may fuel hormone therapy resistance, according to a study by Weill Cornell Medicine investigators.
Researchers maintain brain organoids for longer than ever before
An international team of researchers has maintained brain organoids, three-dimensional models of human brain tissue, for longer than ever before.
New brain wave theory explains cognition and consciousness
A new theory, published in The Journal of Neuroscience by three scientists in The Picower Institute for Learning and Memory at MIT, offers an explanation of how the brain produces cognition and consciousness: It uses traveling waves of rhythmic neural activity to coordinate nimble neural networks with analog computations.
Active screening cuts colorectal cancer death risk drastically
People who take part in screening for colorectal cancer may have as much as 43 per cent lower risk of dying from the disease, according to new estimates published in JAMA Network Open by researchers at Karolinska Institutet and Umeå University in Sweden.
Psychological factors determine maternal readiness to care for newborns
The first days after childbirth are a time of profound change – not only physically, but emotionally as well. Although the rooming-in model, in which mothers and newborns stay together around the clock, is standard practice in maternity wards, not every woman feels ready to care for her baby independently from the very first hours after delivery.
Study: Nearly 8 out of 10 young adults have cardiovascular-kidney-metabolic syndrome
A new scientific study found that nearly 8 out of 10 young adult participants, average age 23 years, had cardiovascular-kidney-metabolic syndrome (CKM syndrome), according to new independent research published today in Circulation: Population Health and Outcomes, a peer-reviewed scientific journal of the American Heart Association.
Longer intervals between meals associated with faster accumulation of chronic diseases
Older adults who typically had longer intervals between meals accumulated chronic diseases more rapidly over time than those with shorter intervals, according to a study from Karolinska Institutet published in the Journal of Internal Medicine.
New review examines why tetanus remains a global health problem
Tetanus is often considered a disease of the past, remembered mainly through childhood vaccinations and warnings about rusty nails.
Review examines how medical imaging foundation models are moved toward clinical use
AI is already widely used for lesion detection, disease classification, and outcome prediction in medical imaging, but most systems remain narrowly designed for one task and depend heavily on expert-labelled data.




