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Three PBMs dominate retail prescriptions in Medicare Part D and Medicaid markets
Just three pharmacy benefit managers (PBM) dominate retail prescriptions in Medicare Part D and Medicaid managed care across much of the country, with markets in in nearly every state considered highly concentrated for at least one program, according to a new study from the USC Schaeffer Center for Health Policy & Economics.
Microbial generalists form planet-wide networks across ecosystems
In a new study published in Cell, scientists in the Bork Group at EMBL Heidelberg reveal that microbes living in similar habitats are more alike than those simply inhabiting the same geographical region.
Choroid plexus enlargement in Long COVID signals cognitive risk
The increased size of, and lesser blood supply to, a key brain structure in patients with Long COVID tracks with known blood markers of Alzheimer's disease and greater levels of dementia, a new study finds.
Anterior crossbite linked to increased tooth loss risk
Crooked teeth or a misaligned bite can cause a whole host of problems, including speech issues and/or difficulty eating or properly cleaning teeth.
Preexisting flu immunity may offer baseline protection against avian influenza
Are seasonal flu antibodies also effective against avian flu? A team from the University of Geneva (UNIGE) has shown that a specific type of antibody associated with the former virus—already present throughout the population—may offer baseline protection against the latter.
Early bone molecular changes signal osteoarthritis progression
Osteoarthritis often goes undetected until cartilage damage is advanced, limiting treatment options. A new study shows that molecular changes in subchondral bone occur earlier and can signal disease progression before cartilage loss.
Type 2 diabetes and hypertension share a genetic link, study shows
Type 2 diabetes and high blood pressure share a genetic link, new research from the University of Surrey, UK and the Université de Lille, France shows.
New genetic model reveals role of keratin 8 in colorectal cancer development
Researchers at Åbo Akademi University have identified a new molecular change in patients with colorectal cancer and developed a genetic disease model that forms tumors in the large intestine, resembling those seen in patients.
Brief oxidative stress promotes brain repair after injury
Oxidative stress is a direct consequence of an excess in the body of so-called "free radicals" – reactive, unstable molecules that contain oxygen.
Study uncovers how bacterial circadian clocks control gene expression
Our circadian clocks play a crucial role in our health and well-being, keeping our 24-hour biological cycles in sync with light and dark exposure.
Mindfulness enables unsedated endoscopy with higher patient satisfaction
A new study has shown that mindfulness helps patients to relax during an endoscopy, allowing doctors to carry out detailed examinations without the need for sedation or general anesthesia.
Study identifies neural mechanism underlying chills during infection
When running a fever during infection, we often feel chills, which prompt us to take action to warm ourselves, such as turning on a heater or adding layers of clothing.
Beta arrestin 1 emerges as key driver of pulmonary hypertension
Researchers have uncovered the pivotal role of a previously overlooked protein in the development of the serious illness.
Study links eye movements to real-time memory retrieval
The eyes may reveal how experiences are recalled according to new Baycrest research that suggests that shifts in eye movements play a critical role in memory retrieval.
Balance depends on preserving inner hair cells in the ear
Led by Mathieu Beraneck, researchers at the University of Paris Cité/CNRS and the University of Barcelona explored the strength of the relationship between a type of inner hair cell in the ear and balance.
Brain differences reveal hidden causes of math learning disability
On a simple math task - indicating which of two amounts is greater - kids with math learning disability get the right answer as often as their good-at-math peers, but behind the scenes, their brains are working differently, a new Stanford Medicine study has found.
Childhood cancer survival varies by tumor stage at diagnosis
A major study by UCL and Fondazione IRCCS Istituto Nazionale dei Tumori in Milan (INT) researchers has for the first time shown in detail how far children's cancer has spread at diagnosis in a way that can be compared between countries.
Influenza viruses can directly impair heart function
Mount Sinai researchers have identified a cellular mechanism linking infections from influenza A viruses (IAVs) to cardiovascular disease, providing critical insights on how influenza can damage the heart and increase the risk of a heart attack or other major cardiovascular event.
FDA label update expands CAR T access for primary CNS lymphoma
Dana-Farber Cancer Institute-led research helped drive an FDA label update for axicabtagene ciloleucel (Yescarta) that removes a prior exclusion for patients with primary central nervous system lymphoma, a rare and aggressive lymphoma of the brain and spinal cord.
Defective fat cells drive metabolic disease in lipodystrophy
Many people may have a dim view of their fat tissue, yet scientists have come to recognize adipose as a necessary and metabolically active organ, carrying out many vital functions within the body.




