Feed aggregator

Human peripheral nerves have a remarkable ability to regenerate after damage. However, when re-growing axons fail to meet their target organ, they can transform into painful neuromas.

Adolescents who use nicotine are more likely to report symptoms of anxiety, depression, and other mental health problems than their peers who do not use nicotine.

The most comprehensive review to date has identified the most effective bipolar disorder treatments across different age groups and mood phases. It was published today in The BMJ.

Stem cell therapies have expanded rapidly, with more than 115 clinical trials involving over 1,200 patients approved by late 2024. The U.S. Food and Drug Administration (FDA) recently approved Ryoncil (remestemcel‑L) for children with steroid‑refractory acute graft‑versus‑host disease, signaling a major shift toward routine clinical use.

The brain's immune cells are increasingly recognized as key players in Alzheimer's disease, but exactly how they change as the disease develops has remained unclear.

Light therapy may improve alertness and attention/reaction time during simulated night shifts, with the strongest benefits appearing after light exposure. Effects on executive function were smaller and largely limited to treatment, while substantial study heterogeneity and limited real-world evidence warrant caution.

A Western dietary pattern was associated with faster attention decline among older adults carrying the APOE ε4 allele, while no significant cognitive associations emerged for a Prudent dietary pattern. However, the Western diet association lost statistical significance after excluding participants with possible baseline cognitive impairment, making the finding exploratory.

. Early-life stress increased SETD7 and H3K4me1 in the ventral tegmental area of mice, creating an epigenetically primed state that heightened later transcriptional, neuronal, and behavioral responses to stress. Reducing Setd7 during development lowered H3K4me1 and weakened these stress-sensitizing effects, identifying a mechanism that may help explain how early adversity leaves lasting biological effects.

Broken String Biosciences, a biotechnology company enabling gene editing teams to accelerate development of safer, more effective genetic medicines, today announced the launch of BaseMap™ ABE. Built on the Company\'s INDUCE-seq® technology, BaseMap ABE extends the platform\'s capabilities to support adenine base editing (ABE) applications.

E-scooter riders admitted with moderate-to-severe trauma showed a distinct injury profile, with proportionally more traumatic brain, vascular, and internal organ injuries than motorcyclists and fewer fractures. Rental-scooter data also linked greater reported injury severity with younger age and female sex, while collision rates varied with area-level deprivation.

The child who plays alone during recess may be perfectly content doing so, according to a new study from the University of Georgia.

A post hoc analysis of 2,970 older SELECT participants found that semaglutide slowed worsening of a 25-protein blood signature that predicts future dementia risk. Over 104 weeks, semaglutide produced larger effects on modeled 5-year than 20-year dementia risk, but whether these biomarker changes translate into less cognitive decline or dementia remains unknown.

A rapid review of 14 studies found that heavy rainfall and flooding were associated with outbreaks and increased incidence of several infectious diseases across Europe, particularly campylobacteriosis and leptospirosis. The authors highlighted major evidence gaps and called for stronger One Health surveillance, public health communication, sanitation, and flood-response planning.

The devastating impacts of marine heatwaves extend far beyond dying coral reefs and declining fisheries, with new research warning these extreme ocean warming events are posing a growing threat to humans' physical and mental health.

A two-year cohort study of 428 people exposed to H5N1-infected birds in England found fewer than 1% met criteria for infection, with no severe disease or secondary human transmission. The findings support continued PPE use, biosecurity, and targeted surveillance while highlighting challenges around occupational exposure, mucosal contamination, and pandemic preparedness.

Researchers at National Jewish Health and partner institutions discovered specific changes in immune cells in the lungs of people with sarcoidosis.

A new research paper was published in Volume 17 of Oncotarget on August 7, 2026, titled "Delayed growth of SK-ES-1 Ewing sarcoma tumor xenografts is associated with reduced Trk and IGF1R pathway markers."

Scientists at St. Jude Children's Research Hospital created a single-cell atlas of a key class of spinal neurons involved in motor coordination. From that resource, they identified a small subgroup of interneurons associated with the speed of rhythmic movements such as walking.

Phthalates, which are chemicals found in plastics, personal care products and hundreds of other consumer goods, may contribute to high blood pressure in pregnant women, according to a study published in the Journal of the Endocrine Society.

A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that while traditional pathological features used to classify aggressive prostate cancer -such as high-grade disease, cancer extending outside the prostate and cancer involving the seminal vesicles- after surgery can help identify patients who are more likely to have worse outcomes, they do not predict who will benefit more from adding hormone therapy to postoperative radiation.