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Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus.

Researchers have elucidated key steps in the ubiquitin tagging of the mutated huntingtin protein, providing hope for future therapies.

Parkinson's disease is a progressive neurodegenerative disorder that affects more than one million people in the United States, with approximately 90,000 new cases diagnosed each year.

Alzheimer's disease is often measured in statistics: millions affected worldwide, cases rising sharply, costs climbing into the trillions.

People with ulcerative proctitis, a milder and more limited form of ulcerative colitis, are not at higher risk of developing rectal cancer than the general population.

More than 30 million people with HIV must take antiretroviral therapy (ART) medications daily to keep the virus under control, according to the Joint United Nations Programme on HIV/AIDS (UNAIDS).

A new case report was published in Volume 12 of Oncoscience on December 23, 2025, titled "Silent toxicity: A rare case of 5-fluorouracil-induced hyperammonemic encephalopathy."

New research suggests the liver plays a previously unrecognized role in bone health, but only in males.

A large cross-sectional study in the Journal of Nutrition Education and Behavior (JNEB), published by Elsevier, examined how psychosocial and environmental factors relate to diet quality among 2,420 adults living in rural and micropolitan communities in New York and Texas.

Predicting tumor progression is one of the major challenges in oncology. Scientists at the University of Geneva (UNIGE) and the Ludwig Institute for Cancer Research have discovered that neutrophils, a type of immune cell, undergo reprogramming when they come into contact with the tumor ecosystem and contribute to its progression.

A new Canadian study has found that people living with dementia (PLWD) are often excluded from research due to assumptions of incapacity and variations in institutional processes.

Researchers evaluate the effectiveness of a novel extracorporeal total artificial lung system to enable bilateral pneumonectomy in patients with severe ARDS.

New evidence suggests that mpox may be circulating quietly among healthy Nigerians, with some infections occurring without the symptoms that typically trigger detection by health authorities.

Two emerging pathogens with animal origins - influenza D virus and canine coronavirus - have so far been quietly flying under the radar, but researchers warn conditions are ripe for the viruses to spread more widely among humans.

Researchers at UC San Francisco have uncovered a new clue to how Epstein-Barr virus (EBV) could contribute to multiple sclerosis (MS), a chronic autoimmune disease that affects nearly one million Americans.

A research team from POSTECH and ImmunoBiome in Korea, led by Professor Sin-Hyeog Im, has uncovered a new mechanism showing how butyrate-a short-chain fatty acid produced by gut commensal bacteria-enhances T follicular helper (Tfh) cell activity to promote antibody production and strengthen mucosal vaccine efficacy.

Announcing a new article publication for BIO Integration journal. Extracellular vesicles (EVs) are membrane-bound nanoparticles secreted by cells and have emerged as promising therapeutic agents for osteoarthritis (OA).

Antioxidants have been marketed as miracle supplements, touted for preventing chronic diseases and cancers; treating COPD and dementia; and slowing aging.

Improving blood flow to the brain by opening a narrowed neck artery may not improve patients' cognitive skills, according to a preliminary late-breaking science presentation at the American Stroke Association's International Stroke Conference 2026.

A large U.S. firefighter cohort study identified personal, occupational, and department-level predictors of serum PFAS concentrations, highlighting both modifiable exposures and persistent background sources. Some protective practices, blood or plasma donation, and drinking water sources were associated with differences in specific PFAS analytes, although causal relationships require further longitudinal study.