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Critical Path Institute® (C-Path), through its Type 1 Diabetes Consortium, today reaffirmed its commitment to strengthening the regulatory-science and evidence infrastructure needed to enable the next phase of therapeutic innovation across multiple stages of type 1 diabetes (T1D).

A small study of healthy Japanese adults found that fatigue was associated with distinct gut microbiome, microbial gene, and fecal metabolite patterns. The findings suggest fatigue may track with altered microbial energy metabolism and oxidative stress-related functional potential, but larger longitudinal studies are needed to test causality and clinical value.

Mayo Clinic researchers have identified a previously unrecognized way the kidneys regulate water balance - an advance that could lead to improved treatments for polycystic kidney disease (PKD) and other disorders. The study, led by Fouad Chebib, M.D., a nephrologist at Mayo Clinic, is published in the Journal of Clinical Investigation.

Screening people with the rare, inherited cancer-causing condition Li-Fraumeni syndrome (LFS) brings both medical and economic benefits to patients and healthcare systems, according to research to be presented to the annual conference of the European Society of Human Genetics today (Tuesday).

New research is shedding light on how comparing ourselves to others affects happiness and life satisfaction.

A new study finds that adults who simply breathe in secondhand cigarette smoke have about 1.5 times more of the toxin cadmium in their blood than people in smoke-free environments.

Understanding why some people stay healthy without developing disease until late in life (have an increased healthspan), whereas others become infirm at a much younger age has important implications for the health of today's ageing population.

New research from large population studies provides invaluable evidence on genome screening of newborn babies to reduce risks from overdiagnosis.

In the largest genetic study of inflammatory bowel disease (IBD) traits to date, researchers have identified a genetic marker that is associated with more severe ulcerative colitis and Crohn's disease – the major forms of IBD.

A multicenter study of 1,333 active drivers with migraine found that 70.6% had experienced headache while driving, with headaches occurring during about 13% of driving sessions. The findings suggest that migraine-related symptoms may impair attention, increase sensitivity to road conditions, and contribute indirectly to driving cessation and accident risk.

Most pandemics start when a pathogen spreads from animals to humans. It's a leading explanation for the COVID-19 pandemic: the SARS-CoV-2 virus, which causes COVID-19, is a cousin to coronaviruses that live in bats.

A long-running Australian cohort study found that personality traits generally matured from early to middle adulthood, with agreeableness and conscientiousness rising and extraversion, openness, and neuroticism declining. People with persistent common mental disorders showed the clearest decline in neuroticism by midlife, but they still had higher emotional instability than peers without persistent mental health difficulties.

Problematic social media use was associated with more frequent self-reported everyday memory failures in 943 Spanish young adults aged 18 to 35. Everyday memory failures statistically accounted for much of the link between problematic social media use and both prospective and retrospective memory lapses.

A UK cost-of-illness projection estimates that direct NHS dental treatment costs for adult caries and periodontal disease will rise by 20%, from £4.42 billion in 2020 to £5.30 billion by 2050. The burden shifts strongly toward older adults and severe disease, supporting prevention and earlier intervention as NHS dental planning priorities.

Dr. Dan Landau, the Bibliowicz Family Professor of Medicine, and a member of the Sandra and Edward Meyer Cancer Center and the Englander Institute for Precision Medicine at Weill Cornell Medicine, has received a Lotus Award from the Pershing Square Foundation for research aimed at uncovering new immunotherapy targets in ovarian cancer.

GLP‑1s do not harm male hormones or fertility after long-term use, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

A local research study led by scientists from the A*STAR Genome Institute of Singapore (A*STAR GIS) has uncovered how the gut microbiome can influence gene activity in the liver by acting on short stretches of regulatory DNA that function like molecular "switches".

In a new JNeurosci paper, Xuanyi Chen and Esti Blanco-Elorrieta, from New York University, explored whether Spanish–English speakers use the same or different brain mechanisms to speak each language.

Just 10 viral particles of the H5N1 bird flu that caused hundreds of influenza outbreaks in U.S. dairy cattle can cause infection in cows, a new study shows.

Researchers are warning that obesity is reshaping the global cardiovascular disease crisis, as trend data covering 204 countries reveal that heart disease now peaks in people aged 50-54 rather than the elderly and increasingly in South Asia, where rates have grown more than three times faster than global averages, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.