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GLP-1 drugs may offer cost-effective treatment for people with knee osteoarthritis and obesity
A new study led by investigators at Mass General Brigham finds that adding novel weight loss GLP-1 drugs semaglutide and tirzepatide to usual care represents a cost-effective treatment strategy for people with knee osteoarthritis and obesity, with tirzepatide providing greater health benefits at lower cost compared to semaglutide.
Personalized risk information does not increase colorectal cancer screening rates
A new Indiana University School of Medicine clinical trial - the largest of its kind to date - found that providing personalized colorectal cancer risk information to patients and their health care providers did not improve screening rates for the deadly ailment.
Limited uptake of over-the-counter naloxone despite initial surge in sales
Sales of the overdose reversal medication naloxone increased after it was made available to the public without a prescription but then dipped quickly in the period following debut of over-the-counter sales, according to a new RAND study.
Boosting PI31 to restore synaptic function and prevent neurodegeneration
One fundamental feature of neurodegenerative diseases is a breakdown in communication. Even before brain cells die, the delicate machinery that keeps neurons in touch-by clearing away protein waste at the synapses-starts to fail.
Neonatal male circumcision rates decline in the United States despite health benefits
Scientific evidence supporting the health benefits of male circumcision - surgical removal of the foreskin from the penis - dates back hundreds of years to observations made by physicians of their circumcised patients.
Researchers receive new funding to advance promising therapy for multiple sclerosis
A Canadian-led international research team, spearheaded by Dr. Fang Liu at the Centre for Addiction and Mental Health (CAMH) has received nearly $800,000 US ($1,137,868 CAD) in new funding to advance a promising therapy for multiple sclerosis (MS).
Children show high exposure to PFAS despite regulatory restrictions
These chemical compounds are highly stable and linger in the environment. Thanks to their water-, oil- and stain-repellent properties, they are widely found in everyday items, such as non-stick pans, waterproof clothing, food containers and fire-fighting foams.
Hair cortisol levels signal mental health risks in children with chronic illness
Long-term stress levels, measured through hair samples, may provide important clues about mental health risks in children with chronic physical illnesses (CPI), according to new research from the University of Waterloo.
Quality of care shapes how patients experience mental health hospitalization
What makes an admission to a mental health unit a more or less traumatic experience, and what role do nurses play in this experience? A study recently published in the Journal of Clinical Nursing focuses on a question that is as sensitive as it is little explored: the perception of quality of care as a factor that can make a big difference in mental health care.
Barriers in NHS services leave autistic people without suicide support
Life-saving opportunities to prevent suicide among autistic people are being missed because systemic barriers make it difficult for them to access NHS support during times of mental health crisis, according to new research.
Scientists discover IC–encoder neurons that shape visual perception
An illusion is when we see and perceive an object that doesn't match the sensory input that reaches our eyes. In the case of the image below, the sensory input is four Pac Man–like black figures.
Scientists map kissing bugs beyond the Americas to assess Chagas threat
Researchers compiled the first comprehensive dataset of 16 non-American triatomine bug species, mapping 396 verified records across Africa, Asia, and Oceania. This resource supports global Chagas disease surveillance by identifying where potential vectors are establishing new populations.
Mediterranean diet during pregnancy cuts babies’ food allergy risk
Researchers found that mothers who closely followed a Mediterranean diet during pregnancy and breastfeeding had infants with lower odds of developing food allergies. High fruit, vegetable, and full-fat dairy intake appeared protective, while higher poultry, red meat, and fish intake during pregnancy increased risk.
Daily meal timing influences longevity risk in adults, study reveals
Researchers analysing Aging Cell data from over 33,000 US adults found a U-shaped link between daily eating window length and mortality. Eating for 11–12 hours per day was tied to the lowest risk, while very short (<8h) or long (≥15h) windows raised death risk, especially in older and White participants.
Study reveals how centenarians preserve youthful immune defenses
Researchers mapped immune cells from centenarians, their offspring, and younger controls across three cohorts using multi-omics single-cell profiling. They found that centenarians retain leaner helper pools but have enhanced cytotoxic and NK cell programs, along with reinforced NK–T communication networks.
SwRI and UT San Antonio advance biosensor coating to streamline production of immunotherapies
Southwest Research Institute (SwRI) and The University of Texas at San Antonio (UT San Antonio) are advancing a smart biosensor coating to streamline the production of immunotherapies for cancer treatments.
NIH awards over 8.6 million grant to advance research on rare developmental synaptopathies
Mustafa Sahin, MD, PhD, Neurologist-in-Chief and Chair of the Department of Neurology at Boston Children's Hospital, and his collaborators have been awarded an NIH grant of over $8.6 million for the third five-year cycle of the Rare Disease Clinical Research Network (RDCRN) project, "Developmental Synaptopathies Associated with TSC, PTEN, SHANK3, and SynGAP1 Pathogenic Variants".
Heart attacks in women under age 65 are caused by factors other than clogged arteries
A new Mayo Clinic study finds that many heart attacks in people under 65 - especially women - are caused by factors other than clogged arteries, challenging long-standing assumptions about how heart attacks occur in younger populations.
UC3M participates in a study to counteract the adverse effects of microgravity on astronauts
A pioneering international project led by prominent female scientists, involving research staff from the Universidad Carlos III de Madrid (UC3M) and promoted by the Spanish Space Agency (AEE), has just completed its parabolic flight campaign in Bordeaux (France).
Mediterranean diet linked to better gum health
People living in the UK and following a diet close to the Mediterranean diet are more likely to have better gum health, with potentially lower amounts of gum disease and inflammation.




