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New human cell model replicates key mechanisms of neurodegenerative diseases

Rss Feed - Thu, 04/23/2026 - 12:23
Researchers at LMU have developed a human cell model that replicates key mechanisms of neurodegenerative diseases - with potential for novel therapies.

Legume and soy consumption may improve COPD symptoms

Rss Feed - Thu, 04/23/2026 - 12:16
Consuming legumes and soy-based foods may help improve symptoms of chronic obstructive pulmonary disease (COPD) by reducing inflammation and irritation, according to a new study in the March 2026 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, a peer-reviewed, open access journal.

Severe strokes significantly increase the risk of progressive dementia

Rss Feed - Thu, 04/23/2026 - 12:11
As stroke severity increases, the risk of progressive cognitive decline and dementia substantially escalates, according to a national study led by Michigan Medicine researchers.

Minimally invasive PTAB shows promise for patients with complex peripheral arterial disease

Rss Feed - Thu, 04/23/2026 - 12:01
New findings from a DETOUR2 substudy show that minimally invasive percutaneous transmural arterial bypass (PTAB) may offer a promising alternative to traditional leg bypass surgery for patients with complex peripheral arterial disease (PAD), even when distal vessel run off is severely limited.

Transcatheter arterialization of the deep veins improves quality of life for no-option CLTI patients

Rss Feed - Thu, 04/23/2026 - 11:59
Data from the PROMISE III trial suggest that chronic limb-threatening ischemia (CLTI) patients with no other treatment options experienced significant quality of life (QoL) improvements after undergoing transcatheter arterialization of the deep veins (TADV).

Transcatheter valve replacement helps patients with limited heart care options

Rss Feed - Thu, 04/23/2026 - 11:54
Findings from the AltaValve™ Early Feasibility Study suggest that patients with a leaky mitral valve have sustained clinical benefits one year following atrial fixation Transcatheter Mitral Valve Replacement (TMVR).

Metabolic health may shape future dementia risk for Latino communities

Rss Feed - Thu, 04/23/2026 - 10:35
Researchers from the University of California San Diego have found that diabetes is linked to changes in measurable biological signals in the blood that are associated with Alzheimer's disease and brain damage in Latino adults.

New approach identified for treating infections with Hepatitis E virus

Rss Feed - Thu, 04/23/2026 - 10:32
Instead of directly attacking the virus, the compound acts on the host cell and prevents infection.

Study maps the evolution of myeloid leukemia in children with Down syndrome

Rss Feed - Thu, 04/23/2026 - 10:26
It may be possible to identify which pre-cancerous cells will develop into a rare type of blood cancer, due to new research showing that a single genetic change drives myeloid leukemia in children with Down syndrome.

Exercise may be safer for children with heart conditions

Rss Feed - Thu, 04/23/2026 - 10:23
Physical activity in children and teenagers with cardiomyopathy (conditions that affect the heart muscle's structure and function, impairing its ability to pump or fill effectively), as well as children with implantable cardioverter-defibrillators (ICDs) may be safer than previous research suggested, according to a new scientific statement from the American Heart Association, published today in the Association's flagship peer-reviewed journal Circulation.

Study links ADHD-related traits to increased chronic pain severity

Rss Feed - Thu, 04/23/2026 - 10:18
A new study, led by researchers from the University of Tokyo, involving nearly 1,000 patients in Japan suggests that attention deficit hyperactivity disorder (ADHD)-related traits may be associated with and may contribute to chronic pain.

New study maps early molecular changes in jaw joint osteoarthritis

Rss Feed - Thu, 04/23/2026 - 06:56
Temporomandibular joint disorders (TMDs) affect a large portion of the global population and are a common source of chronic jaw pain and difficulty in chewing or speaking.

Astrocytes form complex networks across the mouse brain

Rss Feed - Thu, 04/23/2026 - 06:46
Cells long thought to play a secondary role in brain function build their own far-reaching connections, a new study in mice showed. These pathways appear to connect distant regions in ways that have not been mapped before.

Long COVID in children doubles risk of poor grades

Rss Feed - Thu, 04/23/2026 - 05:40
Findings indicate long-COVID leads to academic and social difficulties in children, highlighting the importance of addressing their unique educational needs.

Can exercise or ibuprofen fight chemo brain?

Rss Feed - Thu, 04/23/2026 - 05:18
This study suggests exercise can mitigate cancer-related cognitive impairment, but combining it with ibuprofen offers no additional cognitive benefits.

New gene therapy improves hearing in patients with rare genetic deafness

Rss Feed - Thu, 04/23/2026 - 00:17
A new international study co-led by investigators from Mass General Brigham and the Eye & ENT Hospital of Fudan University shows that a gene therapy for a rare form of genetic deafness successfully restored hearing in most participants, with results lasting up to 2.5 years.

Antisense oligonucleotides reverse rare neurodevelopmental disorder in preclinical models

Rss Feed - Wed, 04/22/2026 - 23:59
Scientists at St. Jude Children's Research Hospital have found they can reverse the effects of HNRNPH2-related neurodevelopmental disorder using antisense oligonucleotides (ASOs) in preclinical models. ASOs are short synthetic nucleic acid strands that target specific messenger RNA.

Experimental drug kills aggressive breast cancer by toxic fat buildup

Rss Feed - Wed, 04/22/2026 - 23:58
An experimental drug targeting triple-negative breast cancer overwhelms cancer cells with toxic fats, according to new tests on human-derived tumors in mice.

GP nurses could deliver effective sleep treatments

Rss Feed - Wed, 04/22/2026 - 23:55
A new Flinders University study shows that nurses working in general practice could play a major role in improving access to sleep‑health treatment, but only if patients and general practice staff are involved in designing these services.

Virtual neurology visits match in-person care outcomes

Rss Feed - Wed, 04/22/2026 - 23:41
For people who see a neurology clinician for the first time, a new study has found that being seen virtually vs. in-person made no difference in how soon they needed more care.

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