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Study reveals wastewater as potential origin for mobile antibiotic resistance genes
Researchers found new evidence that wastewaters are a feasible environment for mobilizing antibiotic resistance genes.
Johns Hopkins Medicine surgeons to receive $21.4 million to advance xenotransplantation research
As part of the worldwide effort to facilitate a research and clinical pathway toward successful xenotransplantation -; the transplantation of living cells, tissues and organs from one species to another -; two Johns Hopkins Medicine surgeons, Kazuhiko Yamada, M.D., Ph.D., and Andrew Cameron, M.D., Ph.D., will receive a total of $21.4 million in funding over the next two years under two sponsored research agreements with biotechnology company United Therapeutics Corporation.
Lab-made antibodies may be able to cure people infected with yellow fever
New research from Oregon Health & Science University and collaborators indicates lab-made antibodies may be able to cure people infected with yellow fever, a virus for which there is no treatment.
Mouse avatars could help design more effective and personalized therapies for multiple myeloma
An international group of researchers, led by Dr. José Ángel Martínez-Climent at the Cima University of Navarra, has created mouse avatars of patients with multiple myeloma to study and develop personalized treatments against this blood cancer, the second most frequent hematological cancer and incurable in most cases.
Drugs to activate STING could help prevent cancer metastasis
A team of scientists at the Sloan Kettering Institute have identified the STING cellular signaling pathway as a key player in keeping dormant cancer cells from progressing into aggressive tumors months, or even years, after they've escaped from a primary tumor.
Study offers a novel therapeutic option to combat antibiotic-resistant pneumonia
Increases in multidrug-resistance in the bacteria Streptococcus pneumoniae have made it the fourth-leading cause of death associated with antibiotic resistance.
Children exposed to pet cats or dogs during infancy may have fewer food allergies
In an analysis of over 65,000 infants from Japan, children exposed to pet cats or indoor dogs during fetal development or early infancy tended to have fewer food allergies compared to other children, according to a study published March 29, 2023 in the open-access journal PLOS ONE by Hisao Okabe from the Fukushima Regional Center for the Japan Environment and Children's Study, Japan, and colleagues.
Study reveals dramatic rise in drug overdose fatalities among older adults in the past two decades
Overdose mortality among people age 65 and older quadrupled over 20 years, suggesting the need for greater mental health and substance use disorder policies addressed at curbing the trend, a new research paper finds.
People with allergic diseases may be at heightened risk of osteoarthritis
People with atopic (allergic) diseases like asthma or eczema may be at heightened risk of the painful and often disabling joint condition, osteoarthritis, finds research published online in the Annals of the Rheumatic Diseases.
AI tool highlights the need to improve diets in long-term care
A detailed analysis of consumed food showed there is a need to improve diets in long-term care (LTC) homes to make them healthier for residents.
FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10
A National Institutes of Health team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.
Children with in utero exposure to maternal COVID-19 infection more likely to develop obesity
Children born to mothers who had COVID-19 during pregnancy may be more likely to develop obesity, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.
How does unprocessed, minimally-processed, and ultra-processed food impact dietary quality?
Researchers assessed the impact of consuming unprocessed, minimally processed, and ultra-processed foods on diet quality.
An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition
Researchers compared the effects of consuming red-fleshed apples and white-fleshed among healthy adults.
Why men should eat more plants: the effect of mediterranean plant-forward diets on health
Researchers performed a systematic review of existing data to investigate whether plant-forward (PF) diets could improve male health.
Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation
Study outlines molecular mechanisms to aid the development of new therapies to manage obesity and associated health disorders.
Clockwork in cancer: the importance of the circadian rhythm in the formation and progression of tumors
Researchers reviewed the importance of the circadian rhythm in the formation and progression of tumors.
A novel approach for analyzing foodborne zoonotic E. coli
Researchers in the US identified extraintestinal Escherichia coli infections using source-related mobile genetic elements.
Maternal weight gain in pregnancy linked to children's risk of neurodevelopmental disorders
In a recent study published in the BMC Medicine journal, researchers in Sweden explored the association between above-optimal maternal gestational weight gain (GWG) and the risk of neurodevelopmental disorders such as intellectual disability, autism spectrum disorder (ASD), and attention-deficit/hyperactivity disorder (ADHD) in offspring.
Next-generation influenza vaccines show greater impact and cost-effectiveness, study suggests
In a recent study published in the BMC Medicine Journal, researchers conducted a modeling study to evaluate the cost-effectiveness and health impacts of the next-generation vaccines against influenza in Kenya.