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In patients with diffuse large B-cell non-Hodgkin lymphoma (DLBCL), the two hallmark post-chimeric antigen receptor (CAR)-T therapy toxicities are extremely rare after two weeks, supporting a shorter, more flexible toxicity monitoring period, according to a study published in Blood Advances.

Since 2009, U.S. high school seniors have reported steep declines in medical use, misuse and availability of the three most commonly prescribed and misused controlled substances for teens, a new University of Michigan study found.

Less than a decade ago, when Dr. Hansruedi Mathys launched an ambitious project to create an annotated library of all the gene readouts stored within 100 individual brain cells, the task felt daunting.

Millions of adults have atrial fibrillation -; an irregular beating of the upper chambers of the heart that yields increased risk of heart failure, stroke and death.

From studying the human genome, to analyzing the way proteins are encoded, or monitoring RNA expression, researchers are rapidly gaining a far richer understanding of the complex genetic and cellular mechanisms that underpin dementia. But there's a catch: While new technologies are revealing myriad avenues for Alzheimer's research, it's impossible to know in advance which research pathways will lead to effective treatments.

Researchers from the University of Otago, Christchurch, have spearheaded the discovery of a protein function which has the potential to guide the development of novel cancer treatment options and improve the diagnosis of various cancers.

New research led by UCLA Health has found that specific genes may be related to the trajectory of recovery for stroke survivors, providing doctors insights useful for developing targeted therapies.

In modern day agriculture, pesticides are essential to ensure high enough crop yields and food security.

Researchers find that esaxerenone is a non-inferior alternative to trichlormethiazide for treating uncontrolled hypertension in Japanese patients. The study confirms similar safety profiles for both drugs.

Deaths from injection-related infections like endocarditis have increased among young people, likely due to the growth of injection drug use and stronger, shorter-acting fentanyl.

Researchers analyzed 1,056 cases of bed bug insecticide exposure in France, revealing a significant rise in poisoning incidents and emphasizing the need for safer pest control methods.

When seemingly healthy people receive an alert from a wearable sensor telling them they might have a respiratory virus-;based on small changes in their unique heartrate, sleep and activity patterns-;what do they do? According to a new study by Scripps Research scientists carried out at the height of the COVID-19 pandemic, only a quarter of people follow up such an alert with an at-home viral test.

Older adults recovering from COVID-19 experience varying degrees of cognitive decline over 2.5 years, with severe cases showing the most significant impact. Early cognitive care and monitoring are crucial for improving outcomes.

Using a wearable device, such as a smart watch, to track health data and symptoms, is supposed to help people monitor their health and address symptoms as quickly as possible to spur positive health outcomes.

In humans and other animals, signals from a central circadian clock in the brain generate the seasonal and daily rhythms of life.

The evolution of retinoblastoma treatment over the past 15 years has resulted in a higher likelihood of vision preservation without compromising survival, according to research released today at the Society of NeuroInterventional Surgery's (SNIS) 21st Annual Meeting.

Researchers discovered that oligodendrocytes, not just neurons, produce amyloid β in Alzheimer's disease, and suppressing their activity improves disease pathology. This finding suggests new therapeutic targets for Alzheimer's treatment.

Prescribing non-steroidal anti-inflammatory drugs (NSAIDs) to people at high risk of harm from them is estimated to cost the NHS in England around £31 million and cause more than 6,000 lost years of good health over 10 years, finds a study published by The BMJ today.

Indiana University School of Medicine researchers have made a significant breakthrough in developing a new gene therapy approach that restores full-length dystrophin protein, which could lead to new treatments for people with Duchenne muscular dystrophy (DMD).

People with high levels of body fat stored in their belly or arms may be more likely to develop diseases like Alzheimer's and Parkinson's than people with low levels of fat in these areas, according to a study published in the July 24, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.