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A new study using serial liquid biopsies to track how metastatic prostate cancer evolves under treatment pressure showed that androgen receptor (AR) alterations consistently emerged and were linked to poorer outcomes across therapies.

What if healing the brain after traumatic injury starts in the gut?

A novel quantitative PET- and MRI-based imaging approach can objectively identify a recently recognized type of dementia--limbic-predominant age-related TDP-43 encephalopathy, or LATE--that is often mistaken as Alzheimer's disease.

Experts from the Translational Research in Neuroimaging and Data Science (TReNDS) Center at Georgia State University will play a key role in the largest study ever conducted to investigate the causes of profound autism in children and develop possible treatments.

In a large UK population cohort, higher weekly alcohol consumption was dose-dependently associated with greater visceral fat mass measured by DXA, independent of total body fat. Heavy drinkers showed over 10% higher proportional visceral fat compared with lower consumption groups, a pattern linked to increased cardiometabolic risk.

Gastric cancer remains the fifth leading cause of cancer-related deaths worldwide. Although its overall incidence has declined, early-onset cases-diagnosed before age 50-display unique biological and clinical patterns.

Ramadevi Subramani Reddy, Ph.D., remembers the neem tree from her childhood in India - a plant her grandmother used to treat everything from fevers to infections.

Despite major advances in diagnostics and treatment, tuberculosis (TB) remains the world's deadliest infectious disease.

Researchers at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center uncovered new evidence that extra copies of a specific chromosome segment - chromosome 1q - may play a key role in the earliest stages of pancreatic cancer development.

New research from UCLA Health suggests that certain inhalers used to treat chronic obstructive pulmonary disease (COPD) are not only less harmful to the environment but can also lead to slightly better patient outcomes.

Researchers showed that pomegranate fruit extract contains substantial levels of non-extractable polyphenols bound within its fibre-rich matrix, significantly increasing its total measured antioxidant capacity. In human neuronal and astrocytic cell lines, the extract reduced hydrogen peroxide–induced oxidative stress, particularly in astrocytes, under in vitro conditions.

Through a series of experiments supported by the National Institutes of Health, Johns Hopkins Medicine (JHM) researchers say they have advanced understanding of how smoking damages the eye and contributes to the development of age-related macular degeneration (AMD), the leading worldwide cause of visual impairment and blindness among people 50 and older.

One to two out of every 100 newborn babies are born with a Congenital Heart Defect (CHD), yet the exact cause remains unclear.

Researchers at the University of Liège have identified a key genetic regulator that enables macrophages to reach full maturity and preserve the health of our organs.

Researchers used single-nucleus RNA sequencing and chromatin accessibility profiling to map human hippocampal neurogenesis across adulthood, aging, and Alzheimer’s disease. They found that chromatin accessibility changes, more than gene expression alone, distinguish healthy aging, preclinical pathology, Alzheimer’s disease, and cognitive resilience in SuperAgers.

It's widely known that breastfeeding impacts the health of both mother and child, but the underlying biology that leads to these effects has been understudied.

The human genome is a rich, complex record of migration, encounters, and inheritance written over thousands of millennia.

CAR T cell therapy has revolutionized the treatment of many blood cancers, but has shown little success against solid tumors, which account for over 85% of all cancers.

A researcher at the University of Missouri has made a promising breakthrough in the quest to help people with amyotrophic lateral sclerosis (ALS), the neurodegenerative disorder commonly known as Lou Gehrig's disease.

Unlike some other forms of lymphoma, advanced stage follicular lymphoma is considered incurable. But a new analysis of long-term data on patients treated for the disease years ago with standard regimens of immunotherapy and a chemotherapy combination known as CHOP suggests that many of those patients can now be considered cured.