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A systematic review and meta-analysis of nine randomized controlled trials involving 6,239 adults with overweight or obesity without diabetes found that subcutaneous semaglutide produced substantially greater reductions in body weight, waist circumference, and C-reactive protein than placebo. The higher dose of 7.2 mg semaglutide showed potential for greater weight loss, although the evidence is largely based on a single trial and requires confirmation.

Parents are an important line of defense against teen vaping, yet many lack the knowledge and tools needed to recognize vaping products, understand their risks and prevent their children from using them.

Spatial transcriptomics is a powerful tool to create a detailed map of not just how genes are expressed in a piece of tissue, but also where genetic activity takes place in different cells and locations within the tissue.

As dogs age, many develop more than one chronic health condition. New research from the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) shows those conditions can dramatically shorten a dog's lifespan, highlighting the importance of managing multiple diseases together rather than individually.

As summer heat waves grow longer and more dangerous, public health officials often must wait months to learn who and how many people were harmed.

There was no difference in major cardiovascular events when statin initiation was based on coronary artery calcium compared with traditional risk factor assessment, according to results presented in a Hot Line session today at ESC Congress 2026.

A recent study found that different dietary fibers can shape the composition and activity of the gut microbiome during early childhood, with xyloglucan, arabinoxylan, and pectin increasing short-chain fatty acid production in laboratory fermentation experiments. Some fibers also supported gut barrier measures and altered inflammatory responses, while observational data linked higher pectin intake with greater microbial diversity in young children.

Researchers found that the distance the eye travels during a rapid gaze shift changes post-saccadic visual sensitivity by altering the spatial-frequency information carried by retinal luminance transients. Larger saccades preferentially enhanced lower-frequency, coarser visual information, while very small saccades could increase the relative visibility of finer, higher-frequency information.

A narrative review found that maternal cannabis use may be associated with differences in breastmilk fat, protein, lactose, and the immune factor secretory immunoglobulin A, but evidence comes primarily from only two human studies and remains limited and inconsistent. The authors stress that maternal diet, food security, socioeconomic circumstances, and other forms of adversity could confound these associations and should be incorporated into future research.

Community first responders did not improve 30-day survival in patients with out-of-hospital cardiac arrest, according to results presented in a Hot Line session today at ESC Congress 2026.

Memory loss is usually thought of as something to address as a person ages. Slip-ups like forgetting someone's name or recognizing a familiar face but not remembering where you know them from are often viewed as issues that arise later in life.

Monkeypox virus used to be transmitted predominantly from animals to humans. In recent years, however, new virus variants have become increasingly capable of spreading from person to person.

Breathing shapes thinking, attention, memory, perception, emotional regulation, and overall mental health by affecting activity in a variety of brain areas.

Mpox (formerly Monkeypox), a viral zoonotic disease, remains a global public health concern because it can spread between animals and humans and among people.

Researchers behind an app designed to support people after skin cancer treatment are inviting former early-stage melanoma patients to take part in its final evaluation tests.

In patients with intermediate−high risk pulmonary embolism, catheter-directed thrombolysis improved short-term clinical outcomes compared with standard anticoagulation therapy alone, according to results presented in a Hot Line session today at ESC Congress 2026.

Triple-negative breast cancer (TNBC) has a frustrating ability to adapt. Although this aggressive form of breast cancer can initially respond well to chemotherapy, cancer cells often find ways to survive, allowing the disease to return and become resistant to treatment.

Lifestyle factors can worsen the effects of genetic causes of male infertility, finds new research that could help explain why men carrying similar genetic mutations often experience different levels of fertility impairment.

Men with prostate cancer have a high risk of heart disease, especially when treated with hormone therapy.

Optical coherence tomography was noninferior to intravascular ultrasound to guide stenting in patients with left main coronary artery disease, according to results presented in a Hot Line session today at ESC Congress 2026.