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Thermo Fisher Scientific expands global biobank leadership through strategic collaboration with PRECISE-SG100K Singapore to advance population-scale proteomics

Rss Feed - Tue, 05/19/2026 - 00:47
Thermo Fisher Scientific Inc., the world leader in serving science, today announced a strategic collaboration with Precision Health Research, Singapore (PRECISE) to advance the PRECISE-SG100K study, one of the region’s most ambitious and diverse population-scale biobank initiatives.

Researchers discover water's role in brain learning and memory signaling

Rss Feed - Tue, 05/19/2026 - 00:43
How do we learn to remember? At the most fundamental level, it's all about chemicals and electricity. Beyond their roles in diet and nutrition, calcium and magnesium work as ions, or charged particles, in the brain.

Combination therapy shows promise in maintaining lower suicidal thoughts over time

Rss Feed - Tue, 05/19/2026 - 00:42
New research published online today in the American Journal of Psychiatry finds that low-dose buprenorphine, given after a single ketamine infusion, significantly sustained reductions in suicidal ideation in adults with major depressive disorder.

Leucovorin use for autism surged after public promotion campaigns

Rss Feed - Tue, 05/19/2026 - 00:27
Researchers from the University of California San Diego found that prescriptions for leucovorin, a drug sometimes used off-label for autism spectrum disorder (ASD), rose sharply among children after widespread media attention and public statements from White House officials.

How antibody-drug conjugates are redefining targeted cancer therapy

Rss Feed - Tue, 05/19/2026 - 00:23
Antibody-drug conjugates are rapidly expanding cancer therapies, with 19 approved globally and many more in development, but their success depends on better targets, payloads, linkers, dosing, and patient selection. The Cell review shows that next-generation ADCs could widen treatment options, but safety, resistance, tumor heterogeneity, and clinical translation remain major barriers.

Mental disorders affect one in three pregnant women, and violence may be a key driver

Rss Feed - Mon, 05/18/2026 - 23:44
A systematic review and meta-analysis of 18 studies involving 17,380 pregnant women found that common mental disorders affected about one-third of participants across studies from Africa, Asia, and South America. The analysis found strong regional variation and identified intimate partner violence as the only statistically significant risk factor, with affected women having about 2.6-fold higher odds of CMDs.

Children's mental health concerns increasingly addressed during primary care visits

Rss Feed - Mon, 05/18/2026 - 23:16
A new study led by researchers at the Harvard Pilgrim Health Care Institute, Boston University, Boston Medical Center, UMass Chan Medical School, and Brown University finds that children's mental health concerns are appearing more often during routine visits with primary care doctors.

Childhood abuse may increase vulnerability to abusive adult relationships

Rss Feed - Mon, 05/18/2026 - 23:13
Experiencing abuse or neglect as a child can increase the risk of being victimised by a romantic partner in adulthood, by impacting personality and mental health development, finds a new study led by University College London (UCL) researchers.

Treatment delays rising among teens with cannabis use disorder

Rss Feed - Mon, 05/18/2026 - 23:09
Teens may turn to marijuana use for many reasons: curiosity, stress relief, peer pressure, help with mental health, or for the positive feelings of being "high." However, there is a difference between casual use and reliance on cannabis to function.

UCLA researchers identify potential drug target for treating Fragile X syndrome

Rss Feed - Mon, 05/18/2026 - 23:04
UCLA Health researchers have identified a potential drug target for treating Fragile X syndrome, the most common genetic cause of intellectual disability and autism that affects roughly 1 in 2,000 boys.

DNA-guided CRISPR system targets RNA and expands Cas12 beyond gene editing

Rss Feed - Mon, 05/18/2026 - 22:54
Researchers developed ΨDNA, a DNA-based CRISPR guide that allows Cas12 enzymes to target RNA with high specificity while retaining compatibility with DNA-editing workflows. The platform detected HCV RNA in clinical samples and enabled programmable RNA knockdown, multiplex targeting, and RNA modification in human cells.

New therapies could help type 1 diabetes care move beyond insulin alone

Rss Feed - Mon, 05/18/2026 - 22:27
Disease-modifying therapies for type 1 diabetes are beginning to move care beyond insulin replacement by targeting immune dysregulation, beta-cell stress, and preservation of endogenous beta-cell function. Teplizumab marks a major clinical milestone, but the review emphasizes that durable metabolic remission will likely require earlier screening, better patient selection, and sequential or combination therapies.

Discovery of memory switch in the brain opens new avenues for dementia therapies

Rss Feed - Mon, 05/18/2026 - 14:34
"Why do patients with dementia or cognitive decline remain stuck in past memories?" KAIST researchers have identified, for the first time in the world, the existence of a "neural switch" in the brain that selectively retrieves the most recent memories.

Sleep complaints highlight Alzheimer's risk in genetically predisposed women

Rss Feed - Mon, 05/18/2026 - 14:21
Sleep complaints may be an important Alzheimer's disease risk factor in older women with a higher genetic predisposition to the disease, according to a new study from researchers at the University of California San Diego.

Integrated care needed for lifelong Polyendocrine Ovarian Syndrome management

Rss Feed - Mon, 05/18/2026 - 14:09
Polycystic Ovary Syndrome, which has just been renamed Polyendocrine Ovarian Syndrome (PMOS), is the most common hormonal and metabolic disorder affecting women of reproductive age, impacting up to 13% of this population and contributing to nearly 40% of infertility cases worldwide.

Exhausted brain immune cells drive aggressive multiple system atrophy

Rss Feed - Mon, 05/18/2026 - 13:37
A rare and fatal brain disorder with no available treatment or cure. One that attacks the nervous system, balance, and the ability to move.

Gut microbiome metabolite butyrate relieves chronic jaw joint pain

Rss Feed - Mon, 05/18/2026 - 09:12
Temporomandibular joint (TMJ) pain is associated with disrupted gut microbiome metabolites. Researchers reveal that butyrate, administered as tributyrin, alleviates pain by restoring histone acetylation and reversing gene regulatory changes in the brain.

Blood test detects tumor DNA to guide advanced cancer treatment

Rss Feed - Mon, 05/18/2026 - 09:09
A blood test that detects tumor DNA circulating in the bloodstream may help select the most effective treatment options for cancer patients whose tumors have started to spread, according to one of the largest randomized controlled trials of its kind presented at the Congress of the European Society for Radiotherapy and Oncology (ESTRO 2026).

New York City's mold-removal program reduces the burden of asthma exacerbations

Rss Feed - Mon, 05/18/2026 - 08:34
The New York City Housing Authority developed Mold Busters, a mold-removal program, in response to a 2013 class-action lawsuit filed by residents suffering from asthma due to mold in their apartments.

Epigenetic research links genetics and environment to mental disorders

Rss Feed - Mon, 05/18/2026 - 08:22
Mental disorders, such as obsessive-compulsive disorder (OCD) and bipolar disorder, can strongly affect daily life.

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