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Study shows wisdom of early US investment in COVID-19 vaccines

Rss Feed - Thu, 04/10/2025 - 01:27
Five years ago, volunteers rolled up their sleeves in the first clinical trial of a vaccine against COVID-19, as the new pandemic surged around them. By a year later, 66 million American adults had gotten at least one dose of a COVID-19 vaccine, at no cost to them.

Now, a new study shows how wise that national investment in testing, buying and delivering the first vaccines was.

Research describes blood disorders and their impact on Ebola patient outcomes

Rss Feed - Thu, 04/10/2025 - 01:07
Announcing a new article publication for Zoonoses journal. Hematologic disorders occur frequently in patients with Ebola virus disease (EVD) and are characterized by one or several abnormalities in blood cells, including hemostasis, which is poorly documented. This study described the hematologic abnormalities of Ebola patients and the impact on the outcomes of patients who were admitted with EVD.

LBNPs: Revolutionizing cancer therapy

Rss Feed - Thu, 04/10/2025 - 00:55
Announcing a new article publication for the BIO Integration journal. Lipid-based Nanoparticles (LBNPs) have emerged as a transformative approach in cancer treatment, offering innovative drug delivery solutions that enhance therapeutic efficacy while minimizing adverse effects.

A dual perspective: Employer and employee views on obesity management

Rss Feed - Thu, 04/10/2025 - 00:38
A new study aimed at understanding perceptions of obesity management and the use of anti-obesity medicine by employers and employees in the US has been published in the peer-reviewed journal Population Health Management.

AI-powered digital twin of mouse visual cortex

Rss Feed - Thu, 04/10/2025 - 00:21
Much as a pilot might practice maneuvers in a flight simulator, scientists might soon be able to perform experiments on a realistic simulation of the mouse brain. In a new study, Stanford Medicine researchers and collaborators used an artificial intelligence model to build a "digital twin" of the part of the mouse brain that processes visual information.

Could your milk choice affect migraines?

Rss Feed - Wed, 04/09/2025 - 23:51
Skim milk consumption is linked to a lower prevalence of migraines in U.S. adults, according to a large NHANES-based study. The association remained significant even after adjusting for lifestyle, diet, and demographic factors.

India, China, and the US will drive global diabetes burden by 2050, study finds

Rss Feed - Wed, 04/09/2025 - 23:02
Global diabetes deaths and disability are rising, particularly in India, China, and the US, with type 2 diabetes (T2DM) driving the trend. Type 1 diabetes (T1DM) burdens are declining, but inequalities are widening, and projections show a steep rise in T2DM by 2050.

Exophiala pneumonia identified in immunocompetent woman with lung disease

Rss Feed - Wed, 04/09/2025 - 23:01
Exophiala, a genus of saprotrophic black fungi commonly found in the environment, is typically associated with cutaneous infections in immunocompromised hosts and rarely manifests as pneumonia.

Study reveals how jet lag affects sleep timing and recovery

Rss Feed - Wed, 04/09/2025 - 22:55
A collaborative study conducted by researchers at the Centre for Sleep and Cognition at the NUS Yong Loo Lin School of Medicine (NUS Medicine) and ŌURA found that while sleep duration recovers quickly, sleep timing and sleep architecture can take significantly longer to realign when traveling across time zones.

Calibr-Skaggs receives FDA approval to test sCAR-T therapy in patients with autoimmune diseases

Rss Feed - Wed, 04/09/2025 - 22:20
Calibr-Skaggs Institute for Innovative Medicines, the drug discovery division of Scripps Research, announced today that the FDA has cleared their investigational new drug (IND) application to study switchable chimeric antigen receptor T cell (sCAR-T) therapy (CLBR001 + SWI019) in patients with autoimmune conditions.

Largest study of osteoarthritis genetics uncovers new drug targets

Rss Feed - Wed, 04/09/2025 - 22:13
Osteoarthritis is the leading cause of disability and chronic pain worldwide, affecting an estimated 595 million people globally.

Breakthrough molecule offers hope for treating rare mitochondrial diseases

Rss Feed - Wed, 04/09/2025 - 22:09
A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic defects disrupt cellular energy production.

Smaller hatching embryos more likely to be genetically healthy

Rss Feed - Wed, 04/09/2025 - 22:06
A new research paper was published in Aging (Aging-US) Volume 17, Issue 3, on March 5, 2025, titled "Reproductive aging, preimplantation genetic testing for aneuploidy, and the diameter of blastocysts: does size matter?"

Certain nasal bacteria could affect COVID-19 vulnerability

Rss Feed - Wed, 04/09/2025 - 22:01
A new study from researchers at the George Washington University has found that certain bacteria living in the nose may influence how likely someone is to get a COVID-19 infection.

Study shows minimal lean muscle mass loss with GLP-1 and GLP-1/GIP therapy for weight loss

Rss Feed - Wed, 04/09/2025 - 21:55
New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) shows that patients using GLP-1 or combined GLP-1 / GIP receptor agonist therapy for weight loss experienced minimal lean muscle mass loss as they lost weight across 6 months of treatment.

MSC-derived extracellular vesicles show promise in treating high-dose radiation injuries

Rss Feed - Wed, 04/09/2025 - 21:50
A new study in the peer-reviewed journal Stem Cells and Development highlights the potential of mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) as a therapeutic strategy for high-dose radiation injuries by promoting hematopoietic recovery and improving survival.

Heavy drinking linked to increased risk of brain lesions

Rss Feed - Wed, 04/09/2025 - 21:46
Heavy drinkers who have eight or more alcoholic drinks per week have an increased risk of brain lesions called hyaline arteriolosclerosis, signs of brain injury that are associated with memory and thinking problems, according to a study published on April 9, 2025, online in Neurology®, the medical journal of the American Academy of Neurology.

Study explores impact of parental Alzheimer’s on tau protein spread in the brain

Rss Feed - Wed, 04/09/2025 - 21:43
While some studies have suggested that having a mother with Alzheimer's disease may put you more at risk of developing the disease, a new study finds that having a father with the disease may be tied to a greater spread of the tau protein in the brain that is a sign of the disease, according to a study published on April 9, 2025, online in Neurology®, the medical journal of the American Academy of Neurology.

Gut microbes and metabolites reveal how lifestyle changes help prevent type 2 diabetes

Rss Feed - Wed, 04/09/2025 - 21:42
Researchers identified 502 blood metabolites linked to prediabetes and type 2 diabetes, with 143 tied to the gut microbiome. The study shows how lifestyle interventions like diet and exercise can modify metabolomic profiles to support glucose control.

Protein linked to Parkinson's also found to drive melanoma growth

Rss Feed - Wed, 04/09/2025 - 21:22
A small protein involved in neurodegeneration leading to Parkinson's disease also drives a type of skin cancer known as melanoma, new research led by Oregon Health & Science University finds.

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