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New insights into sperm metabolism could transform infertility treatments
Michigan State University scientists have pinpointed the molecular "switch" that supercharges sperm for their final sprint to an egg - a breakthrough that could reshape infertility treatments and pave the way for safe, nonhormonal male contraceptives.
Living near Superfund sites increases risk of aggressive breast cancer
Women living close to federally designated Superfund sites are more likely to develop aggressive breast cancers - including the hard-to-treat triple-negative subtype - according to new studies from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.
HEPA purifiers do not fully reduce classroom viral exposure
In a secondary analysis of a study of 200 classrooms, Mass General Brigham researchers found respiratory viral exposures were still high in those with HEPA purifiers, suggesting additional interventions are needed.
Lifestyle choices and hormonal imbalances can impact men's reproductive health
A new research paper was published in Volume 12 of Oncoscience on September 30, 2025, titled "Lifestyle and hormonal factors affecting semen quality and sperm DNA integrity: A cross-sectional study."
Targeting SIRT7 offers new strategy against liver fibrosis
Liver fibrosis, a progressive scarring of the liver tissue, represents a major global health burden with limited treatment options.
Blood biomarkers offer hope for early detection of interstitial lung disease
UVA Health lung researchers are developing a promising approach to detecting patients at risk of interstitial lung disease (ILD), an increasingly common condition that is a leading reason for lung transplants.
Changing bodily perception unlocks childhood memories
New research has discovered that briefly altering how we perceive our own body can help unlock autobiographical memories – potentially even those from the early stages of childhood.
Natural nasal microbes offer broad-spectrum antiviral protection
Respiratory viral diseases pose severe threats to animal health and global food security, especially in intensive pig farming systems.
Understanding the impact of chikungunya on children
Chikungunya is a vector-borne disease that affects both adults and children. While global efforts are ongoing to tackle chikungunya in adults, progress in addressing pediatric chikungunya remains inadequate.
Decoding the signaling networks and metabolic dysregulation underlying sepsis
Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction.
Multidimensional regulation of stem cell fate by the cohesin complex
Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D genome architecture.
Study reveals how DKK3 triggers smooth muscle cell transformation in aortic aneurysm
Abdominal aortic aneurysm (AAA) is a life-threatening vascular disorder that primarily affects elderly males.
Advances in nanomaterials revolutionize therapy for myocardial ischemia-reperfusion injury
Ischemic heart disease is the leading cause of death globally, causing approximately 9 million deaths annually.
Researchers identify key role of lactylation in driving aortic dissection
Recently, a research team led by Professor Jian-Xun Wang and Professor Tao Yu from Qingdao University made a significant breakthrough in understanding the role of lactylation modification in aortic dissection (AD).
Genetic study reveals unique mutations in Chinese patients with hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM), a common genetic heart disorder, is often caused by mutations in sarcomere-related genes.
A blood test breakthrough for detecting heart damage from cancer therapy
Treatments for cancer are continuously improving, but they can still cause debilitating, even fatal, side effects.
Study links housing type to cardiovascular death risk among older adults in Japan
A 6-year cohort study conducted by researchers from Japan, comprising nearly 39,000 older adults found that people living in rental flats and owner-occupied detached houses face higher risks of cardiovascular death compared with those in owner-occupied flats.
Higher screen exposure in early years tied to weaker academic achievement
Higher levels of screen time in early childhood are associated with lower scores in reading and mathematics on Ontario's standardized tests, with each additional hour of daily screen time associated with a 10 per cent drop in the likelihood of achieving higher academic levels.
Discovery of unique brain cells sheds light on progressive multiple sclerosis
Scientists have identified an unusual type of brain cell that may play a vital role in progressive multiple sclerosis (MS), likely contributing to the persistent inflammation characteristic of the disease.
How much caffeine is safe during pregnancy? New review finds no clear threshold
Caffeine's impact on pregnancy is nuanced; moderate consumption may not lead to major complications, but risks to fetal growth persist without a safe threshold.