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Adrenomedullin hormone contributes to insulin resistance in obesity-associated type 2 diabetes
The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study.
Childhood and adult trauma may play a role in endometriosis pathogenesis
The University of Barcelona has participated in an international study that has found new evidence linking traumatic experiences and stressful events with endometriosis, a chronic systemic inflammatory disease characterized by the presence of endometrial-like tissue outside the uterus.
Are school takeaway bans just a policy illusion? Students say yes
Most young people are unaware of takeaway exclusion zones near schools, and policies limiting new outlets fail to address unhealthy food access from convenience stores and delivery apps.
Researchers uncover brain mechanisms that help overcome instinctive fears
Researchers at the Sainsbury Wellcome Centre (SWC) at UCL have unveiled the precise brain mechanisms that enable animals to overcome instinctive fears.
Dysregulation of RNA-binding proteins in rheumatoid arthritis and osteoarthritis
Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of RNA-binding proteins (RBPs), which are critical for alternative mRNA splicing and translational control in rheumatoid arthritis (RA).
Can parents' diet predict childhood obesity? New research weighs in
Children’s eating habits are strongly influenced by their parents' weight status, with those having overweight or obese parents consuming more carbohydrates and exhibiting higher obesity risks.
Neoantigen vaccine sparks powerful immune defense against kidney cancer
A personalized neoantigen cancer vaccine generated strong immune responses in renal cell carcinoma patients, leading to long-lasting T cell expansion and no disease recurrence after 40 months.
GPT-4 gives physicians an edge in complex case management
A new study shows that GPT-4 enhances physicians’ management reasoning, improving clinical decision-making beyond conventional resources.
Research unveils synergistic effects of tau and beta-amyloid in Alzheimer's
A research team from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has discovered that the two key pathological hallmarks of Alzheimer's-tau protein and beta-amyloid-affect brain circuits in distinct yet synergistic ways, particularly those linked to memory and emotions.
Fruit fly research uncovers brain signals behind alcohol-induced insomnia
Alcohol use disorder, which affects over 10% of Americans, can lead to persistent and serious insomnia. Difficulties falling asleep and staying asleep can last even after months of sobriety, increasing the risk of relapse.
New method for detecting inflammation could revolutionize disease diagnosis
Nearly every disease has an inflammatory component, but blood tests can't pinpoint inflammation in specific organs or tissues in the human body.
New study identifies potential drug targets for heart failure
Heart failure remains a substantial burden for patients due to its high prevalence and limited therapeutic options. Heart failure is classified into two major clinical subtypes- heart failure with preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF).
Brazilian study reveals new pathways for preventing atrial fibrillation
A recent Brazilian study published in Nature Cardiovascular Research has highlighted promising pathways for preventing and treating atrial fibrillation, a condition that significantly raises the risks of stroke and dementia.
Granzyme K identified as key trigger of complement system in autoimmune diseases
Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system-a group of proteins that patrols our body, ever vigilant for signs of infection or injury
RUFY1-RET fusion identified as mechanism of resistance to lorlatinib in lung cancer
A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled "Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 rearranged non-small cell lung cancer: A case report."
Many Americans unaware of heart disease risks during pregnancy
Pregnancy-related deaths in the U.S. have risen 140% over the past three decades with heart disease a major cause, according to the American Heart Association.
KAIST team discovers molecular switch to reverse cancer cells
Professor Kwang-Hyun Cho's research team has recently been highlighted for their work on developing an original technology for cancer reversal treatment that does not kill cancer cells but only changes their characteristics to reverse them to a state similar to normal cells.
Study explores the impact of respiratory bacteria on RSV severity
Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections in children under two years old, resulting in significant morbidity and a heavy economic burden on healthcare systems worldwide.
Testosterone found to worsen heart attack damage
Testosterone worsens the damage caused by a heart attack by increasing the number of white blood cells released from the bone marrow.
Gut microbes may hold the key to easing anxiety
Could the key to easing anxiety be hidden in our gut? Scientists from Duke-NUS Medical School and the National Neuroscience Institute have discovered a crucial connection between gut microbes and anxiety-related behavior.