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Understanding key risk factors behind shoulder injuries in athletes and aging adults
Shoulders are, in many ways, a marvel. One shoulder has four separate joints, packed with muscles, that allow us to move our arm in eight different major ways, giving us the most degrees of freedom of any joint in the body.
Study reveals brain circuit behind apathy in advanced cancer
The fatigue and lack of motivation that many cancer patients experience near the end of life have been seen as the unavoidable consequences of their declining physical health and extreme weight loss.
Unlocking the power of MDA5 protein modifications in antiviral defense
Cleveland Clinic virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how human bodies detect and respond to viruses and viral replication.
Genetic test outperforms PSA and MRI in spotting deadly prostate cancer early
A UK study found that using a polygenic risk score to identify men at highest genetic risk of prostate cancer significantly improved detection of clinically important disease. This approach caught aggressive cancers that standard PSA and MRI screening would have missed.
Can psychedelics break compulsive eating habits in obesity?
A review by Oxford researchers explores how psychedelics like psilocybin and LSD may help disrupt compulsive eating behaviors in subsets of obese individuals. The paper outlines proposed neurobiological, epigenetic, and gut-brain mechanisms while emphasizing the need for human trials.
Combined use of alcohol and cannabis could fuel addiction risks
Many young adults drink alcohol and use cannabis together, at the same time, as a coping mechanism or to relieve stress.
Six early life factors found to influence obesity risk in South Asian children
Researchers at McMaster University have identified six key factors in the first three years of life that influence the trajectory of obesity in South Asian children.
Epigenetic discovery offers hope for reducing addiction relapse
New research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and thereby the formation of strong drug-related memories, which can trigger relapse in individuals with substance use disorders (SUDs).
Sleep enhances memory for life events over the long term
While sleep's positive impact on cognition has long been recognized, Baycrest researchers have revealed that a good night's sleep may actively enhance memory rather than simply protect it from decline.
Researchers uncover a new genetic cause of neurodevelopmental disorders
A seminal study from researchers at the Icahn School of Medicine at Mount Sinai and their collaborators in the United Kingdom, Belgium, Spain, the Netherlands, and Iceland has uncovered a new genetic cause of neurodevelopmental disorders (NDDs).
Smoking places financial strain on disadvantaged households
Disadvantaged households have higher rates of smoking, putting pressure on their household budgets, University of Queensland research has found.
Eye tracking reveals untapped potential in individuals with multiple disabilities
Using eye-tracking - a technique for recording and analysing eye movements - a team from the University of Geneva (UNIGE) has shown that individuals with multiple disabilities can improve their social and emotional skills.
New antibiotic compound emerges as strong candidate in the fight against MRSA
The development of new antibiotics to treat superbugs and other bacterial infections is a global priority, with the rate of infections that cannot be treated with current antibiotics rising and presenting one of the biggest threats to human health.
USC researchers reveal brain activity behind post stroke urinary incontinence
A new USC-led study using functional magnetic resonance imaging (fMRI) reveals the neural mechanisms that contribute to urinary incontinence, a common condition affecting stroke survivors that has a significant impact on their quality of life.
New study sharpens focus on genetic causes of asthma
Genome wide association studies (GWAS) have identified hundreds of genome regions containing thousands of genetic variants associated with asthma, but it's still not clear which variants have an actual causal link to the disease.
Are food additives linked to type 2 diabetes?
This study identifies food additive mixtures associated with higher type 2 diabetes risk, urging a reevaluation of safety assessments for combined additives.
Mindfulness and cognitive behavioral therapies offer lasting relief for chronic low back pain
Researchers compare the long-term effectiveness of mindfulness and CBT among adults with opioid-treated chronic low back pain.
New quinoline-based antiviral shows strong promise against SARS-CoV-2
Researchers develop quinoline-based drug with inhibitory activity against the SARS-CoV-2 papain-like protease (PLpro).
AI-driven personalized nutrition shows promise in improving gut health
Researchers examine the impact of AI-based personalized nutrition programs on the gut microbiome of healthy individuals.
Rapid growth of blood cancer driven by a single genetic ‘HIT’
A new study has unveiled when chronic myeloid leukaemia, a type of cancer that affects the blood and bone marrow, arises in life and how fast it grows.