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Black patients with AML experience earlier onset and poorer outcomes
Compared with white patients, Black patients with acute myeloid leukemia (AML) were on average more than five years younger at diagnosis, more than 30% more likely to die of their disease, and more than 20% more likely to die of any cause, according to an analysis of data conducted over a 34-year period and supported by the National Cancer Institute (NCI) is a component of the U.S. National Institutes of Health.
Study finds no specific harms linked to hydroxyurea exposure during pregnancy
Taking the sickle cell drug hydroxyurea during or shortly before pregnancy does not appear to cause specific issues in newborns, according to the first prospective study of pregnancies involving hydroxyurea exposure.
Challenges and opportunities in delivering gene therapies for sickle cell disease and beta thalassemia
The first study assessing the real-world commercial roll-out of gene therapies for sickle cell disease and beta thalassemia offers lessons learned to inform best practices as manufacturers and medical centers prepare to meet growing demand for gene therapies in the coming years.
New evidence shows hematopoietic cell transplantation offers durable relief for sickle cell disease
Patients who underwent hematopoietic cell transplantation for sickle cell disease saw high rates of survival without disease symptoms and low rates of severe side effects or complications years after their procedure, according to a new study.
Most sickle cell patients face long delays for recommended pain relief, study shows
A new study finds that only one in three patients visiting emergency departments (EDs) for severe pain associated with sickle cell disease received appropriate opioid-based pain-relieving medications within the first hour as recommended by the American Society of Hematology (ASH) and National Heart, Lung, and Blood Institute (NHLBI).
Study reveals how viral social interactions shape resistance to antivirals
Interactions among viruses can help them succeed inside their hosts or impart vulnerabilities that make them easier to treat. Scientists are learning the ways viruses mingle inside the cells they infect, as well as the consequences of their socializing.
New Lancet case study series highlights how social forces shape patient health
In November, The Lancet, one of the world's most esteemed medical journals, launched a new monthly series of case studies that goes beyond clinical diagnoses to illuminate the social and cultural forces that contribute to each patient's condition.
Brainwide circuitry mapping reveals how psilocybin drives therapeutic neural rewiring
An international collaboration led by Cornell University researchers used a combination of psilocybin and the rabies virus to map how – and where – the psychedelic compound rewires the connections in the brain.
Phonological processing skills continue to influence text reading fluency in adolescents
Psycholinguists from the Center for Language and Brain found that phonological processing skills continue to influence text reading fluency in 15-to-18-year-old adolescents.
Study finds mixed reviews of virtual nursing programs among bedside nurses
Hospitals struggling to attract and retain enough registered nurses at the bedside are implementing alternative strategies to ensure patients get needed nursing care.
Genetic variant linked to higher heart failure risk in children with myocarditis
A genetic variant is likely putting some children suffering with myocarditis - inflammation of the heart muscle - at higher risk of developing heart failure, which can be fatal, according to a study published today in Circulation Heart Failure.
Tenascin C as a key to restoring muscle regeneration in aging
As we age, the muscles we rely on for daily activities tend to become less reliable. With enough decline, even normal movements such as getting out of bed become risky.
Restrictive state abortion laws may affect frontline care in obstetric emergencies
Although the United States does not guarantee health care as a right, federal law mandates that hospitals cannot deny anyone lifesaving emergency care.
New atomic structure reveals how NBCn1 transporter protein aids breast cancer cell survival
UCLA scientists have characterized the structure and function of a key survival protein in breast cancer cells that helps explain how these tumors resist environmental stress and thrive in acidic, low-oxygen environments that would normally be toxic to healthy cells.
Researchers highlight five pathways through which microplastics can harm the brain
Microplastics could be fueling neurodegenerative diseases like Alzheimer's and Parkinson's, with a new study highlighting five ways microplastics can trigger inflammation and damage in the brain.
Modern pollutants and ancient genetic variants could explain why some women develop endometriosis
A new study suggests that certain genetic differences, passed down from ancient human ancestors, and exposure to common present-day chemicals could explain why some women are more likely to develop endometriosis.
Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer
Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows quickly, spreads early and lacks the hormone receptors that make other breast cancers treatable with targeted therapies.
Smoking fewer cigarettes does not eliminate cardiovascular disease risk
In a study funded by the National Heart, Lung, and Blood Institute, new research from Johns Hopkins Medicine adds to existing evidence that smoking fewer cigarettes does not eliminate cardiovascular disease risk, and quitting entirely is the most effective strategy for improving health.
Study shines light on how P2X4 receptor can be inhibited
A study carried out by the University of Bonn and the University Hospital Bonn throws light on how an important receptor can be inhibited.
Study shows how respiratory rhythm shapes memory processes
First and foremost, we breathe in order to absorb oxygen - but this vital rhythm could also have other functions. Over the past few years, a range of studies have shown that respiration influences neural processes, including the processing of stimuli and memory processes.




