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Young adults with prediabetes who maintained higher Life’s Essential 8 (LE8) cardiovascular health scores were far less likely to progress to type 2 diabetes over 13 years. Ideal LE8 profiles, particularly healthy weight, blood pressure, physical activity, and sleep, were strongly associated with regression to normal glucose levels.

Mutations in a gene known as CPD play a crucial role in a rare form of congenital hearing loss, an international team of researchers has discovered.

Global surveillance data from over 23 million infections reveal persistently high and uneven antibiotic resistance, with the greatest burden in regions lacking diagnostic capacity and robust health systems. WHO warns that without urgent action on surveillance, stewardship, and equitable access to effective antibiotics, AMR will continue to undermine modern healthcare worldwide.

University of Arizona Cancer Center researchers will study the potential effects of the loss of the Y chromosome in the development and progression of bladder cancer thanks to a grant of up to $6.5 million over seven years from the National Cancer Institute.

Loneliness and social isolation are linked to a heightened risk of death from cancer as well as from all causes among those with the disease, finds a pooled data analysis of the available research published online in the open access journal BMJ Oncology.

Poorer health is linked to a higher proportion of votes for the populist right wing political party, Reform UK, indicates an analysis of the 2024 general election voting patterns in England, published online in the open access journal BMJ Open Respiratory Research.

Researchers demonstrated that pancreatic β cells from type 2 diabetes donors can partially regain glucose responsiveness when cultured outside the diabetic environment. This recovery, driven by specific gene expression changes, identifies JAK inhibitors as potential therapeutic candidates to restore β-cell function.

This review uncovers how aging reshapes immunoglobulins, particularly IgG, IgM, and IgA, driving inflammation, cellular senescence, and tissue degeneration. By dissecting B-cell dysfunction, glycosylation changes, and Fc receptor pathways, it reveals immunoglobulins as both biomarkers and potential therapeutic targets in aging.

The NHS incurs an estimated £340 million in additional healthcare costs annually due to weight-related health problems in children – but it is not just obesity driving the costs.

Researchers at Karolinska Institutet in Sweden have discovered that some natural killer cells, NK cells, temporarily reside in our organs and then leave them via the lymphatic system.

Hospice care aims to bring comfort, peace, and dignity to patients at the end of life. Yet for the growing number of Americans with dementia who enter hospice, their course is often long and unpredictable - making it especially important to ensure treatments align with each person's goals and stage of illness.

E. coli bacteria are typically harmless, but certain strains, known as Avian Pathogenic E. coli (APEC), can cause serious illness in poultry, leading to significant financial losses and animal welfare issues.

New study shows that just 30 minutes of less sitting each day can improve the body's ability to utilise fats and carbohydrates for energy production.

More than a million people around the world rely on cochlear implants (CIs) to hear. CI effectiveness is generally evaluated through speech recognition tests, and despite how widespread they are, CI sound quality is typically not considered an indicator of users' quality of life.

A new research paper was published in Volume 17, Issue 9 of Aging-US on August 30, 2025, titled, "Glycocalyx-targeted therapy prevents age-related muscle loss and declines in maximal exercise capacity."

A peer-reviewed viewpoint article published today in Psychedelics by Prof. Xiaohui Wang and colleagues examines the therapeutic potential of psychedelic substances for treating stress-related psychiatric disorders through novel neurobiological mechanisms.

Researchers led by Dr. Roberto Goya-Maldonado at the University Medical Center Göttingen have identified a rapid physiological marker that predicts which patients with major depression will respond to magnetic brain stimulation therapy.

In a compelling Genomic Press Interview published today in Genomic Psychiatry, Dr. Bruce M. Cohen discusses results and insights that are reshaping international approaches to understanding and treating neuropsychiatric disorders.

Hearing the sound of their mother's voice promotes development of language pathways in a premature baby's brain, according to a new Stanford Medicine-led study.

Findings indicate H5N1 virus stability in raw-milk cheese for 120 days, emphasizing the need for revised safety measures in dairy products to protect health.