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A new review highlights how human evolution has shaped the presence of pathogenic variations in DNA damage repair (DDR) genes, offering a new perspective on why modern populations face increased cancer susceptibility.

This systematic review found that yoga and Buddhist meditation were associated with favorable gut microbiota and metabolite profiles in four human studies involving healthy adults. However, because participants largely followed vegetarian or vegan diets and no randomized controlled trials were included, the findings cannot prove that meditation alone reshapes the gut microbiome.

A new scientific focus on extrachromosomal circular DNA (eccDNA) is opening transformative possibilities for disease detection, monitoring, and personalized medicine.

A new review article highlights the powerful influence of long non-coding RNAs (lncRNAs) in regulating natural killer (NK) cells, revealing promising opportunities to enhance immune responses and improve treatment strategies across multiple diseases.

The research team led by Professor Zhongyu Xie from Sun Yat-sen University revealed a new mechanism by which Pim1 regulated Th17 cell differentiation through mitochondrial metabolism.

As neuroscience strives for generalizability and equity, understanding human brain diversity across populations is crucial.

Pancreatitis is a complex inflammatory disease driven by both genetic and environmental factors. It poses substantial clinical challenges due to a lack of disease-modifying therapies.

Real time data collected during the 2024 Noto Peninsula earthquake response show that unclear tasks and command structures, and lack of meal- and rest breaks increased self-reported fatigue among disaster responders.

A new study reveals that many oral cancers are no longer driven by traditional risk factors like smoking or Human papillomavirus infection.

A new study led by a team from the University of Ottawa takes a major step forward in understanding how a heart attack can dramatically reshape brain function and trigger neurological effects, from depression and anxiety to different types of cognitive decline.

For many people living with HIV, today's treatments can suppress the virus and dramatically improve health. But even when HIV is controlled, damage to the gut caused by the disease can persist, fueling chronic inflammation linked to serious health problems.

A study led by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has identified a mitochondrial "checkpoint" that enables dendritic cells to efficiently activate T lymphocytes against viruses and tumors.

The optimal management strategy for adults with immune-tolerant (IT) chronic hepatitis B infection remains undefined. This study aimed to investigate the efficacy and predictive factors of a pegylated interferon (Peg-IFN)-based treatment strategy in IT patients with chronic HBV infection.

A study by researchers at the University of Birmingham has identified a new biomarker for response to a specific cancer therapy, treating children with Ewing Sarcoma and other tumor types.

Recently, the research group led by Dr. Dechao Feng, Lecturer at University College London (UCL) and Distinguished Research Fellow at Zhejiang Provincial People's Hospital, published a review entitled "Intratumoral Androgens and Genetic Variants Driving Therapy Resistance in Prostate Cancer".

A new review highlights how synthetic biology, AI, and spatial omics could transform ligand-receptor discovery from one-by-one searches into network-level mapping.

While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for the metabolite.

Steatotic donor livers are highly susceptible to post-transplant dysfunction; however, the underlying mechanisms remain incompletely understood.

Scientists and physicians should advocate to protect the vaccine research infrastructure that has saved an estimated 154 million lives over the past 50 years, according to a new commentary by researchers at Weill Cornell Medicine and the University of Washington.

A new brain imaging study has found no evidence of widespread brain inflammation in patients suffering from prolonged symptoms after COVID-19 infection. Instead, the most severe long COVID symptoms were associated with increased brain activity in regions involved in mood and emotion.