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A prospective UK Biobank study of 103,684 adults found that higher peak 30-minute stepping cadence was associated with lower all-cause and cardiovascular mortality across several daily step-count levels. The findings indicate that both total daily steps and the intensity of the most active stepping minutes may matter for mortality risk, particularly for people who find higher step totals difficult to achieve.

Short-term coffee aroma exposure was followed by reductions in several negative mood measures and an increase in an EEG-derived relaxation index in 20 healthy young adults. Heart rate and HRV did not change significantly, and the uncontrolled study cannot establish that coffee aroma caused the observed responses.

Brain tumors develop within an organ that changes substantially with age. A new review in Ageing and Cancer Research & Treatment examines evidence that the aging brain microenvironment may influence brain tumor progression, treatment resistance, and cognitive outcomes.

A test to determine if people who report out-of-body experiences could identify objects in another room produced results no better than chance, but afterward something strange happened: Two participants described, unprompted, researchers' locations and activities behind closed doors.

New research has uncovered that how the brain responds to anticipated rewards plays a key role in building psychological resilience after a traumatic experience.

An international team of researchers led by the University Hospital and University of Bonn, as well as the universities of Edinburgh, Basel and Pennsylvania, has identified a previously unrecognized form of inherited retinal degeneration caused by a specific variant in the EFEMP1 gene.

Extreme heat has become more common-both research and lived experience document this-but when it arrives is a different question.

People with autism spectrum disorder (ASD) in the United States face a 14-year deficit in life expectancy, according to a new study by researchers at Columbia University Mailman School of Public Health and University of Colorado Anschutz.

Nephrotic syndrome is caused when the filtering system in the kidneys is damaged, allowing large amounts of protein to leak into the urine.

For over 60 years, scientists have debated a basic structural question about cone photoreceptors, the cells that let vertebrates see color: are their light-sensing disk membranes closed off inside the cell, or are they open to the extracellular space? In non-mammalian species, the answer is clear - cone disk membranes typically stay continuous with the surrounding plasma membrane and are therefore open.

Increasing numbers of Australian women are using a blood test to assess their fertility, but new research suggests it may not provide the answers many are looking for.

Senior urban development decision-makers have revealed there is currently little incentive to consider public health impacts when shaping towns and cities, according to a new study that highlights the potential of an innovative economic valuation tool to address the problem.

Solute carriers (SLCs) are specialized transport proteins that control the movement of nutrients, ions and neurotransmitters across cell membranes and are essential for brain metabolism and neuronal communication.

As thousands of children start secondary school, experts have called for children to be given more opportunities for independence before they hit adolescence.

Patients with locally advanced head and neck squamous cell carcinoma (HNSCC) whose tumors responded to neoadjuvant immunochemotherapy (ICT) and who underwent less extensive surgery had high disease-free survival and organ preservation rates.

The non-profit Boehringer Ingelheim Stiftung supports LMU clinician-scientist Daniel Kotlarz through its Rise up! program.

A common liver condition thought to be harmless could be dramatically increasing the risk of heart disease, kidney failure and premature death, according to a new review led by University of Manchester and Northern Care Alliance NHS Foundation Trust researchers.

Compassion, trust and person-centerd care must be at the heart of supporting people experiencing suicidal distress, according to a leading Adelaide University suicide prevention expert.

Exposure to light during the nighttime is linked to important and potentially harmful changes to the structure and function of the heart, according to a study of more than 11,000 people published in the European Heart Journal today (Thursday).

Researchers applied six proteomic aging clocks to serum samples from a phase 2a trial of rentosertib in people with idiopathic pulmonary fibrosis and found treatment-associated shifts toward younger predicted biological-age profiles, particularly with the 30 mg twice-daily regimen. Additional proteomic analyses linked treatment to changes in senescence, metabolism, growth-factor signaling, and fibrosis-related pathways, although the study could not determine whether these effects reflected genuine geroprotection rather than disease modification.