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New insights into survival of breast cancer cells in the bone marrow
A study from researchers at the University of Michigan and the University of California San Diego has shed light on a previously poorly understood aspect of breast cancer recurrence: how cancer cells survive in bone marrow despite targeted therapies.
Common farming pesticides linked to rheumatoid arthritis
Exposure to specific pesticides is linked to increased rheumatoid arthritis risk, with notable dose-response trends for malathion and carbofuran among older licensed applicators in the Agricultural Health Study.
Cancer cells block T-cell activation, but new therapies restore immune defenses
Cancer cells impair monocyte-mediated T-cell activation by disrupting inflammatory pathways in the tumor microenvironment. Restoring balance through PGE2 inhibition and IFN-I enhancement could renew immune defenses and improve immunotherapy outcomes.
Childhood diabetes rates surge globally
Researchers investigate global trends in childhood diabetes rates and different factors that contribute to its incidence.
Aging reduces cancer risk by limiting cell regeneration
When it comes to cancer, aging is a double-edged sword, researchers are increasingly learning.
Ethiopian children struggle with malnutrition due to low animal product intake
Affordability and lack of awareness drive low consumption of animal products in Ethiopian children, prompting experts to plan interventions.
College students’ loneliness outweighs screen time in causing insomnia
Being lonely is a bigger hurdle to a good night's sleep for college students than too much time at a computer or other electronic screen, a new study by Oregon State University suggests.
Scientists identify molecular mechanism behind idiopathic autism
Autism is a neurodevelopmental disorder characterized by difficulties in communication and social behavior. Approximately 20% of cases are linked to a specific genetic mutation, but the origin of the remaining 80%, known as idiopathic autism, remains a mystery.
Brain signature of resilience suggests a new way to recovery from trauma
Researchers at UCSF find a brain signature of resilience in mice that suggests a new way of treating severe depression.
Fructose consumption linked to accelerated tumor growth in cancer models
Fructose consumption has increased considerably over the past five decades, largely due to the widespread use of high-fructose corn syrup as a sweetener in beverages and ultra-processed foods.
New discovery offers hope for treating aggressive adenoid cystic carcinoma
A new editorial was published in Oncotarget's Volume 15 on November 22, 2024, entitled "B7-H4: A potential therapeutic target in adenoid cystic carcinoma."
Study highlights bias in ACL injury rate metrics for women athletes
A new study by the Harvard GenderSci Lab in the British Journal of Sports Medicine reveals systematic biases in a key metric used in estimates of sex disparities in ACL injury rates in sports.
New research sheds light on how monkeys avoid hepatitis B infection
Hepatitis B virus (HBV) infection is a leading cause of chronic liver diseases, that spreads among individuals through blood or body fluids.
Tumor secreted DNA triggers immune response against liver metastasis Special...
Specially packaged DNA secreted by tumor cells can trigger an immune response that inhibits the metastatic spread of the tumor to the liver, according to a study led by researchers at Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and Korea's Yonsei University.
Biomarker discovery offers hope for aggressive breast cancer treatment
A new study led by Lund University in Sweden has solved a years-old mystery: which patients with aggressive breast cancer are helped by a targeted cancer treatment that had been under development but was shelved.
The heart has a mini-brain that controls its rhythm
New research from Karolinska Institutet and Columbia University shows that the heart has a mini-brain - its own nervous system that controls the heartbeat.
Altered gait contributes to long-term knee problems after ACL surgery
For people with an injured anterior cruciate ligament (ACL) in the knee, surgical ACL reconstruction (ACLR) is an effective treatment for restoring joint stability, however, many treated patients still develop additional long-term knee problems, such as knee osteoarthritis.
Innovative approach predicts most effective medication for cancer patients
A new method can improve treatment for patients with chronic myeloid leukemia by predicting which medication will be most effective.
Heart medication may slow the progression of Huntington's disease
Research indicates β-blockers may reduce the risk of motor diagnosis and slow symptom progression in Huntington's disease, suggesting new management approaches.
New AI tool maps millions of CD8+ T cells to advance disease research
The scAtlasVAE model integrates scRNA-seq data to create a CD8+ T cell atlas, enhancing understanding of immune responses in inflammation and cancer.