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Scientists and physicians should advocate to protect the vaccine research infrastructure that has saved an estimated 154 million lives over the past 50 years, according to a new commentary by researchers at Weill Cornell Medicine and the University of Washington.

A new brain imaging study has found no evidence of widespread brain inflammation in patients suffering from prolonged symptoms after COVID-19 infection. Instead, the most severe long COVID symptoms were associated with increased brain activity in regions involved in mood and emotion.

A team of researchers at the National Institutes of Health (NIH) have unveiled new details about the events GLP-1 receptor agonists trigger within neurons, which have been largely unexplored until now.

In a new study published in Nature Immunology, researchers at Boston Children's Hospital demonstrated that pairing the original COVID-19 mRNA vaccine with an immune system enhancer, known as an adjuvant, extended the duration of the vaccine's protection in mice from a few months up to two years.

As non-surgical cosmetic procedures grow in popularity, accessibility and affordability, new Griffith University research has created two new measures to assess people's attitudes and motivations towards cosmetic procedures.

It is known that the antiepileptic drug valproate increases the risk of developmental disorders in unborn children.

Nearly 1.2 billion people worldwide are living with a mental disorder, nearly double the number recorded in 1990.

People with private health insurance can jump the public healthcare queue by using private health services instead. Is there really anything wrong with that?

People with opioid use disorder (OUD) are at increased risk of contracting human immunodeficiency virus (HIV). While there are effective interventions that can substantially reduce HIV incidence and opioid overdose, like pre-exposure prophylaxis (PrEP) and medications for opioid use disorder (MOUD), many patients still face barriers to accessing and staying engaged in care.

Among the younger part of the population, sleep problems, anxiety, and depression are widespread and growing issues.

Researchers found that more than half of urban rats sampled from low-income communities in Salvador, Brazil, carried active pharmaceutical ingredients in their brain tissue. These pollutants were associated with altered zoonotic infection patterns, including lower Leptospira infection probability in rats carrying azithromycin and higher Capillaria infection probability in rats carrying citalopram.

Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the functional genome, the working portion of our DNA that helps make each person unique. Put simply, a single gene can be edited in different ways to produce multiple sets of instructions.

Younger generations appear to be experiencing poorer health earlier in life than previous generations, according to a review of studies comparing national birth cohort datasets involving tens of thousands of people across the UK born since 1946.

Not all broken genes fail in the same way: some simply stop working, while others interfere with what still works.

A new preclinical study led by researchers at The University of Texas MD Anderson Cancer Center and Weill Cornell Medicine has uncovered genetic and cell-state adaptive mechanisms that drive resistance to KRAS inhibitors in patients with KRAS-mutant colorectal cancer.

An 8-month low-calorie diet plus behavioral support helped older adults with overweight or obesity and persistent atrial fibrillation lose weight safely, with no intervention-related serious adverse events. However, the LOSE-AF trial found no meaningful improvement in AF symptoms, rhythm control, AF burden, cardiac remodeling, or further AF procedure rates compared with usual care.

Michael Koob, PhD, and his team from University of Minnesota Medical School have been selected to join the Collaborative Research Network (CRN), an international, multidisciplinary, multi-institutional network working to address high-priority research questions about Parkinson's disease, through a $6 million grant awarded by Aligning Science Across Parkinson's (ASAP), in partnership with The Michael J. Fox Foundation for Parkinson's Research (MJFF).

Why are conditions such as chronic stress, depression, cardiovascular disease, fragmented sleep, and aging all associated with a higher risk of dementia? In a new review piece in Science, University of Rochester Medicine neuroscientist Maiken Nedergaard, MD, DMSc, proposes that many of these seemingly different conditions may converge on the same biological problem: disruption of a sleep-dependent brain rhythm that helps clear waste from the brain.

Hair, nails, and horns, all made up of keratin, are some of the hardest and most resilient structures in animals. Inside zebrafish cells, keratin plays a distinct role, giving them the strength they need to move together as a coherent tissue while modulating the driving forces behind their movement during early development. But what happens when keratin is missing?

The Sin Nombre virus – a hantavirus that can cause a deadly respiratory disease in humans – may be more widespread among rodent populations in parts of the Pacific Northwest than previously recognized.