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Distinct tau chemical signatures redefine diagnosis across neurodegenerative diseases

Rss Feed - Sat, 01/31/2026 - 08:53
Tau protein aggregation is a shared feature in over 20 neurodegenerative diseases (collectively referred to as "tauopathies"). New research led by Boston Children's Hospital challenges the current "one-size-fits-all" approach to diagnosing and treating these tauopathies.

Genetic ancestry influences tumor biology and survival in head and neck cancers

Rss Feed - Sat, 01/31/2026 - 07:18
Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help explain why African-American patients survive for half as long as their counterparts of European ancestry, according to a new review study led by researchers from the University of Maryland School of Medicine's (UMSOM) Institute for Genome Sciences (IGS) and the University of Maryland Greenebaum Comprehensive Cancer Center (UMGCCC).

Solvent-free method improves drug solubility using mesoporous silica

Rss Feed - Sat, 01/31/2026 - 07:16
A large share of medicines developed today may never reach patients for a surprisingly simple reason: they cannot dissolve well enough in water.

Lower hinge of immunoglobulin G acts as a critical immune control hub

Rss Feed - Sat, 01/31/2026 - 07:06
The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control hub, according to a study by researchers at Science Tokyo.

Research highlights global neurosurgical workforce shortages and systemic barriers

Rss Feed - Sat, 01/31/2026 - 06:58
Neurological disorders contribute to nearly nine million deaths globally each year, and an estimated 22.6 million new cases require neurosurgical attention annually, of which approximately 13.8 million require surgical intervention.

Human life span found to be far more heritable than previously believed

Rss Feed - Sat, 01/31/2026 - 06:42
An analysis of twin cohort data suggests that human life span is far more heritable than previously believed.

Research reveals a link between defective DNA repair and immune-driven inflammatory disease

Rss Feed - Sat, 01/31/2026 - 06:36
Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature aging and embryonic lethality in mice.

Most Americans would consider swapping classic Super Bowl party fare for plant-based options, poll finds

Rss Feed - Sat, 01/31/2026 - 06:24
It is estimated that Americans will consume 1.48 billion chicken wings during the Super Bowl, but a new Physicians Committee for Responsible Medicine/Morning Consult poll finds that most Americans, 56%, would consider trying a plant-based alternative such as Baked Buffalo Cauliflower Bites while watching the New England Patriots and Seattle Seahawks on Feb. 8.

Sex-specific analysis uncovers unique disease pathways and treatment implications

Rss Feed - Sat, 01/31/2026 - 06:20
Biological differences between women and men led to variations in the appearance and progression of many diseases, which influenced diagnosis and response to treatments.

Foreign legislation strongly influences domestic novel psychoactive substance deaths

Rss Feed - Fri, 01/30/2026 - 23:44
Ric Treble is a retired forensic chemist, who has studied the development of novel drugs for over thirty years.

Study offers hope of preventing hydrocephalus in children

Rss Feed - Fri, 01/30/2026 - 22:00
Hydrocephalus is a life-threatening condition that occurs in about 1 in 1,000 newborns and is often treated with invasive surgery. Now, a new study offers hope of preventing hydrocephalus before it even occurs.

Researchers identify key factor to help improve treatment for glioblastoma

Rss Feed - Fri, 01/30/2026 - 21:55
A groundbreaking study from Brown University Health researchers has identified a crucial factor that may help improve treatment for glioblastoma, one of the most aggressive and common forms of adult brain cancer.

Nasal spray vaccine prevents infection from highly pathogenic H5N1 virus

Rss Feed - Fri, 01/30/2026 - 21:52
Researchers at WashU Medicine have developed a nasal vaccine against the highly pathogenic H5N1 avian influenza virus, or bird flu, which has jumped from wild birds to livestock to humans.

Neural circuits in flies provide insights into human eating

Rss Feed - Fri, 01/30/2026 - 21:36
Why do we sometimes keep eating even when we're full and other times turn down food completely? Why do we crave salty things at certain times, and sweets at other times? The answers, according to new neuroscience research at the University of Delaware, may lie in a tiny brain in an organism you might not expect.

Characteristic features of bone marrow metastasis from non-hematolymphoid malignancies

Rss Feed - Fri, 01/30/2026 - 21:31
Bone marrow metastasis (BMM) from non-hematolymphoid malignancies with resultant cytopenia(s) can mimic primary hematolymphoid disorders. This study aimed to investigate the clinical and pathological characteristics of BMM from non-hematopoietic tumors.

Family remains central to elder care responsibilities in America

Rss Feed - Fri, 01/30/2026 - 21:29
Americans believe that the family as a whole-especially a spouse or partner-is responsible for caring for an older adult.

Dynamic viral markers predict treatment response in hepatitis B

Rss Feed - Fri, 01/30/2026 - 21:26
The rate of functional cure (HBsAg loss) remains unsatisfactory following pegylated interferon (PEG-IFN) treatment in chronic hepatitis B. To optimize PEG-IFN administration, this study aimed to evaluate virological markers to predict functional cure and/or hepatitis B e antigen (HBeAg) loss.

King’s researchers help transform UK mental health research infrastructure

Rss Feed - Fri, 01/30/2026 - 21:24
King’s researchers will help transform mental health data, clinical trials and industry partnerships as part of the UK Government’s Mental Health Goals programme.

Scientists uncover new mechanism initiating gene transcription

Rss Feed - Fri, 01/30/2026 - 21:12
Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular mechanism by which the transcription of genetic information from deoxyribonucleic acid (DNA) into ribonucleic acid (RNA) can be initiated.

Metacognitive therapy speeds return to work and saves costs

Rss Feed - Fri, 01/30/2026 - 21:10
Many people with different mental health problems can be absent from work for a long time. But new results give hope that more people can recover and return to work sooner.

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