Feed aggregator

Ceramides-lipid molecules in cells that affect many physiological functions including cell differentiation, migration, and death-and their metabolites have been implicated in the development of cancer and other conditions.

Chronic oral inflammation may impair female fertility by triggering a systemic immune response that affects the ovaries.

This review shows how rising humid heat threatens the health benefits of nature-based recreation in tropical cities. The authors call for heat-smart urban planning, targeted advisories, and inclusive strategies that keep outdoor activity safe, accessible, and beneficial.

Snakes are threatened with extinction in many places around the globe. Disease, often caused by parasites or fungi, is thought to be one of the key factors alongside habitat destruction.

The outer regions of the brain, the cortex, have specific layers of different cells - neurons - that are similarly ordered among all mammals, from tiny mouse brains to huge elephant brains.

This global analysis of 152,943 endurance runners found that nationality, gender, age, and race distance were significantly associated with running performance from 1999 to 2024. Men were faster across all distances, women were generally older in longer races, and runners from Kenya, Ethiopia, Japan, and the United States showed distinct participation and performance patterns.

Cancer diagnosis can be challenging, and delayed diagnosis can allow cancer to progress, complicating treatment.

Experimental infection studies in lactating Holstein cows showed that H5N1 B3.13 can infect the bovine mammary gland at doses as low as 10 TCID50, producing extremely high viral loads in milk. However, the virus did not transmit to sentinel cows through repeated exposure to contaminated milking equipment or through close contact under high-biocontainment conditions, suggesting that real-world dairy-farm spread depends on additional cofactors.

Persistent or severe nausea during pregnancy was linked to higher maternal anxiety and depressive symptoms across gestation. The study found little consistent evidence that nausea worsened most perinatal outcomes, suggesting it may serve mainly as a clinical warning sign for psychological burden.

A small case-control study linked higher Dietary Inflammatory Index scores with progressive vitiligo, suggesting that pro-inflammatory dietary patterns may be associated with disease occurrence or progression. The findings support further research into diet, inflammation, and the gut-skin axis as potential targets for vitiligo prevention and management.

Europe is facing a growing chronic liver disease threat, according to a new Series published today in The Lancet Regional Health – Europe, that engaged more than 75 co-authors from 30 countries and was led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by the "la Caixa" Foundation.

The paper describes a single-center randomized controlled trial testing whether an Indian Adapted Mediterranean Diet can reduce dietary inflammation in adults with stable coronary artery disease or moderate-to-high cardiovascular risk. The protocol will assess changes in the Dietary Inflammatory Index, inflammatory biomarkers, cardiometabolic risk factors, body measurements, and metabolic hormones over six months.

The research findings of experts from Roswell Park Comprehensive Cancer Center will be featured during the American Society of Clinical Oncology (ASCO) annual meeting May 29 to June 2 at McCormick Place in Chicago.

Space missions expose crews to months of isolation, confinement and extreme stress. An international study led by Jan Schmutz, professor at the Department of Psychology at the University of Zurich, and Andrea Cantisani, psychiatrist and research associate at the University of Bern, has investigated how such conditions affect team dynamics during a ten-month overwintering mission at Concordia Station in Antarctica.

Megan Sweet slices tumors. A normal day in the lab finds the Virginia Tech graduate student with hands deep inside a refrigerated metal box, pulling a mounted mouse-grown tumor incrementally closer to a razor-sharp blade.

The vagus nerve connects the brain to major organs throughout the body and plays important roles in many bodily functions.

New research shows that gay dating apps during travel can bring excitement and connection - but also emotional exhaustion, catfishing, and vulnerability.

Changes in land-use across Southeast Asia over the past 15 years are worsening air quality and contributing to thousands of excess deaths each year, according to a study led by researchers from Nanyang Technological University, Singapore (NTU Singapore).

Nonalcoholic fatty liver disease (NAFLD) is a prevalent metabolic disorder with a complex pathogenesis. Although epitranscriptomic modifications such as N6-methyladenosine (m6A) have been implicated in NAFLD, the role of N1-methyladenosine (m1A) and its regulators is largely unexplored.

Recently, a research team led by Professors Dahong Zhang and Qi Zhang from the Urology Department and the Institute of Urology at Zhejiang Provincial People's Hospital and the Translational Medicine Center discovered that a bladder tumor-targeting polyarginine peptide, R11, can directly bind to actin, destabilize the G-actin tetramer, and trigger the cascade breakdown of the actin-plectin-vimentin/ITGβ4 axis (referred to as the "cytoskeletal domino effect").