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Immune Cell 'Messengers' Could Save Crumbling Bones - New Hope For Joint Pain Sufferers

Rss Feed - Tue, 04/15/2025 - 20:55
A recent study has uncovered a potential breakthrough in treating osteonecrosis of the femoral head (ONFH), a debilitating bone disease that causes severe pain and joint collapse.

Understanding the natural history of SCN8A-related epilepsy disorders

Rss Feed - Tue, 04/15/2025 - 20:51
Researchers from the Epilepsy Neurogenetics Initiative (ENGIN) at Children's Hospital of Philadelphia (CHOP) have completed a comprehensive natural history study of SCN8A-related disorders, which represent a spectrum of neurological symptoms.

Study identifies a new key factor contributing to aggressive nature of pancreatic cancer

Rss Feed - Tue, 04/15/2025 - 20:42
Pancreatic cancer is one of the most aggressive cancers and has one of the lowest survival rates-only 10% after five years.

Researchers analyze the mutational landscape of TMB-high colorectal cancer tumors

Rss Feed - Tue, 04/15/2025 - 13:09
Colorectal cancer (CRC), a type of cancer that affects the large intestine and rectum, is one of the leading causes of cancer-related deaths worldwide.

Study reveals a novel link between body fat and anxiety

Rss Feed - Tue, 04/15/2025 - 13:01
In a groundbreaking study, researchers at McMaster University have revealed a novel link between body fat (adipose tissue) and anxiety, shedding light on the intricate relationship between metabolism and mental health.

Researchers develop drug cocktail to target enteroviruses

Rss Feed - Tue, 04/15/2025 - 12:39
Enteroviruses are a group of viruses that cause everything from the common cold to meningitis, polio, type 1 diabetes, and much more. Over 100 different types have been described by researchers, and millions of people are infected each year.

Reserpine shows promise in treating retinitis pigmentosa in rat studies

Rss Feed - Tue, 04/15/2025 - 12:24
New studies in rats suggest the drug reserpine, approved in 1955 for high blood pressure, might treat the blinding disease retinitis pigmentosa.

Heart valve abnormality raises long term risk of dangerous arrhythmias

Rss Feed - Tue, 04/15/2025 - 10:06
People with a certain heart valve abnormality are at increased risk of severe heart rhythm disorders, even after successful valve surgery.

Congenital heart surgery in children remained safe during the COVID-19 pandemic

Rss Feed - Tue, 04/15/2025 - 09:59
Major reallocation of healthcare services during the COVID-19 pandemic meant that elective surgery in children with congenital heart disease (CHD) was significantly reduced, so that those needing urgent, lifesaving and emergency surgery could be treated.

Radiation from CT scans linked to future cancer risks in children and adults

Rss Feed - Tue, 04/15/2025 - 09:34
Radiation from imaging could lead to lung, breast and other future cancers, with 10-fold increased risk for babies.

Inherited genetic variants play crucial role in cancer development and behavior

Rss Feed - Tue, 04/15/2025 - 09:11
A new multicenter study by researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with the National Cancer Institute-funded Clinical Proteomic Tumor Analysis Consortium (CPTAC) and colleagues around the world, has discovered that the genes we are born with-known as germline genetic variants-play a powerful, underappreciated role in how cancer develops and behaves.

Small antibody fragment shows potential for non-hormonal contraception

Rss Feed - Tue, 04/15/2025 - 08:55
A new study from Karolinska Institutet shows how a small antibody fragment can block fertilization by targeting a key protein on the surface of the egg.

Inherited mutations in healthy cells may contribute to cancer development

Rss Feed - Tue, 04/15/2025 - 08:41
Most cancer genome studies have focused on mutations in the tumor itself and how such gene variants allow a tumor to grow unchecked.

Do disasters delay early cancer diagnoses?

Rss Feed - Tue, 04/15/2025 - 07:58
Rates of colorectal cancer (CRC) diagnoses dropped during and shortly after Hurricanes Irma and Maria and the COVID-19 pandemic in Puerto Rico, according to a recent analysis. However, late-stage diagnoses eventually exceeded expectations, suggesting that limited access to cancer screening services due to these disasters likely hindered timely CRC diagnoses. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.

Cannabis use linked to increased dementia risk after emergency care

Rss Feed - Tue, 04/15/2025 - 07:41
Individuals with an emergency department (ED) visit or hospitalization due to cannabis were at 23% and 72% greater risk of a new dementia diagnosis within five years compared to individuals with an ED visit or hospitalization for any other reason or the general population, according to a new study published in JAMA Neurology.

Digital lifestyle program cuts diabetes risk by 46% in prediabetics, study of 130k+ adults reveals

Rss Feed - Mon, 04/14/2025 - 22:38
A large study of 133,764 adults found that a voluntary digital lifestyle program reduced 10-year diabetes risk by 45.6% in prediabetics and doubled remission rates in diabetics, with significant improvements in triglycerides, insulin resistance, and inflammatory markers like hs-CRP.

Lithium shifts circadian rhythms early in bipolar disorder and may offer clues to treatment response

Rss Feed - Mon, 04/14/2025 - 22:01
A randomized controlled trial shows that lithium treatment in bipolar disorder patients reduces daytime activity, advances its onset time, and increases volatility in circadian rest-activity patterns. These changes appear early and independently of mood, offering promise as early biomarkers of treatment response.

Blood test detects Parkinson’s years before symptoms appear using RNA markers

Rss Feed - Mon, 04/14/2025 - 20:42
A new study identifies a blood-based biomarker that detects pre-symptomatic Parkinson’s disease by measuring the ratio of specific nuclear and mitochondrial transfer RNA fragments. The test outperforms standard clinical tools and may also reflect disease mechanisms related to impaired protein synthesis.

Gen Z orders 6x more takeout online than seniors—how age reshapes global food habits

Rss Feed - Mon, 04/14/2025 - 20:14
Over half of adults in five countries used online food retail platforms in the past month, with the highest use in Mexico and the US. Younger adults, men, ethnic minorities, and families with children were significantly more likely to order food online.

Why measles is back in the U.S. and what doctors must know now

Rss Feed - Mon, 04/14/2025 - 19:37
Measles is making a troubling comeback in the U.S., driven by declining vaccination rates and rising vaccine hesitancy. Pediatric infectious disease experts provide clinical guidance to help healthcare providers recognize, manage, and prevent measles in today’s outbreak-prone environment.

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