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Rare dendritic cells may promote immune tolerance in metastatic cancer
This study was co-led by Steven Blum, MD. Gary Reynolds, MD, PhD, Samuel Klempner, MD, and Alexandra-Chloé Villani, PhD, jointly supervised the work at the Krantz Family Center for Cancer Research within the Mass General Brigham Cancer Institute and the Mass General Brigham Center for Immunology & Inflammatory Diseases (CIID).
Food insecurity disproportionately affects LGBTQ+ adults in Massachusetts
More than half of LGBTQ+ adults in Massachusetts experienced food insecurity in 2024, according to a new study published in JAMA Network Open.
New long-acting HIV treatment offers hope for drug-resistant infections
A new long-acting HIV treatment could expand options for people who have trouble taking daily pills and whose virus is resistant to some commonly used HIV drugs, according to a new UC San Francisco study.
U.S. hospital closures outpace openings in rural and urban communities
More hospitals across the U.S. are closing than opening, and urban hospitals are closing at the same rate as rural ones, according to a new study led by Harvard T.H. Chan School of Public Health.
Disrupted circadian rhythms may influence tumor immunity and cancer spread
Epidemiological studies link light at night (LAN), shift work, chronic jet lag (CJL), and core clock gene mutations to higher cancer risk and aggressive spread, especially in breast and colorectal cancer.
Consuming fat before carbohydrates reduces post-meal blood glucose
In treating diabetes, post-meal elevation of glucose levels is an important therapeutic target. Existing clinical studies indicate that eating vegetables, protein, or fat before carbohydrates can moderate a post-meal rise in blood glucose, pointing to the potential of meal-sequencing as a simple and sustainable dietary strategy.
Brief safety reminders help reduce harmful clinical AI decisions
As artificial intelligence (AI) becomes increasingly capable of assisting with health care tasks, a new study by researchers at the Icahn School of Medicine at Mount Sinai has found that adding a brief safety reminder reduced potentially harmful choices by AI models in clinical scenarios.
Longer sleep duration linked to diabetic kidney disease risk
People with type 2 diabetes who sleep longer may have an increased risk of developing or worsening existing diabetic kidney disease, according to a study published in the Journal of the Endocrine Society.
Blood biomarkers help track gut pathology in celiac disease
Celiac disease is an autoimmune condition in which the immune system reacts adversely to gluten. Eating gluten causes inflammation in the gut, which can damage the intestine and impair its ability to absorb nutrients.
Hyponatremia risk varies among individual second-generation antipsychotic drugs
Antipsychotics are used to treat schizophrenia, along with bipolar disorder and major depressive disorder. However, these medications can be associated with hyponatremia, a serious reduction in blood sodium levels.
Excess adiposity may alter the immune environment of airways to promote lung cancer
In a recent study of more than a thousand individuals, greater adiposity, or excessive body fat or fatty tissue, specifically in the abdomen, was associated with lung cancer.
Potassium-rich DASH diet does not cause hyperkalemia in individuals taking blood pressure drugs
Increased consumption of potassium-rich foods that are part of the Dietary Approaches to Stop Hypertension (DASH) diet did not raise blood potassium to dangerous levels in people taking medications to lower their blood pressure, according to preliminary research presented at the American Heart Association's Hypertension Scientific Sessions 2026.
Value-based messaging increases openness to vaccination in vaccine-hesitant adults
Vaccine-hesitant adults were more likely to consider getting a COVID-19 vaccine when public health messages acknowledged distrust of government and affirmed values such as personal liberty, a new study found.
Combination therapy overcomes immunotherapy resistance in glioblastoma
Scientists at The Wistar Institute have identified a combination treatment that overcomes two of the biggest barriers to immunotherapy in glioblastoma.
Shared family factors influence screen use and mental health problems in young people
Shared family factors, such as genes and upbringing, are likely to explain a large part of the link between high screen use and mental health problems in young people.
Study explains how sickle cell variant shapes malaria parasite infections
Malaria is one of the deadliest infectious diseases on the planet, afflicting people for the entirety of recorded history.
Spanish homicide study reveals hidden victims of mental illness
In recent decades, the social and legal perception of people with mental disorders who commit crimes has changed. Initially, people with mental disorders were considered dangerous.
Universal germline genetic testing catches missed cancer risks in older patients
Universal germline genetic testing of nearly 40,000 patients with solid tumors detected a substantial proportion of inherited gene variants that would have been missed by the standard germline testing approach that excludes those over age 50.
Vaccination protects the immune system from long-term infection damage
Vaccination not only prevents disease caused by acute infection but also protects against long-term immune-related sequelae that can follow an acute viral infection.
ELRIG and The Protein Society announce keynote speakers for Protein Sciences in Drug Discovery 2026
ELRIG, a not-for-profit, volunteer-led organization dedicated to the global drug discovery community, and The Protein Society, an international, not-for-profit, scholarly society, with the mission to provide forums for the advancement of research into protein structure, function, design and applications, today announced the keynote speakers for Protein Sciences in Drug Discovery 2026.




