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Blood sugar migration to saliva fuels cavity development in type 2 diabetes patients
Individuals with type 2 diabetes often have a higher incidence of tooth decay, but the underlying mechanisms remain unclear.
Standard UK road crossing times may be unrealistic for older people with limited mobility
Road crossings need to slow down to allow people with mobility issues and older pedestrians enough time to use them, research has indicated.
Social media affects children's ability to concentrate, study reveals
Children who spend a significant amount of time on social media tend to experience a gradual decline in their ability to concentrate.
Lower dose of immunotherapy for malignant melanoma improves results
According to a new study, lower doses of approved immunotherapy for malignant melanoma can give better results against tumors, while reducing side effects.
Study reveals the hidden toll of sudden cardiac death in type 1 and type 2 diabetes
A Danish nationwide study found that people with type 1 and type 2 diabetes have markedly higher rates of sudden cardiac death than the general population, especially at younger ages. At age 30, people with diabetes lose many years of life, with several of those years specifically attributable to sudden cardiac death.
Young Australians are staying on antidepressants for longer than ever
Long-term antidepressant use in Australia increased steadily between 2014 and 2023, with the largest relative rise seen among adolescents and young adults aged 10 to 24 years. Treatment duration also lengthened over time, while apparent dose reduction efforts remained limited, raising concerns about deprescribing practices.
Virtual diet and exercise program shows promise in reducing lymphoma treatment side effects
Patients undergoing treatment for lymphoma often experience adverse side effects that can be so severe that they stop or slow treatment.
Kiwifruit intake boosts vitamin C in skin and supports dermal structure
Study shows that increasing dietary vitamin C intake with kiwifruit raises vitamin C levels in both the dermis and epidermis through active transport from the bloodstream. Higher skin vitamin C levels were associated with increased skin density and epidermal cell proliferation, but not with improved UV protection or measurable increases in new collagen markers.
Shingles vaccination is linked to fewer dementia diagnoses and deaths in older adults
A large quasi-experimental study in Wales shows that eligibility for shingles vaccination is linked to fewer new mild cognitive impairment diagnoses and lower dementia-related mortality. Benefits appear strongest in women and are observed at multiple stages of the dementia disease course.
Parental leniency toward binge drinking is tied to heavier alcohol use in Greek students
Parental permissiveness toward heavy episodic drinking is higher among Greek-affiliated students and their parents during the transition from high school to college. Students who perceive greater parental approval of heavy drinking report more frequent alcohol use, with this relationship differing by Greek affiliation.
Human researchers still outperform AI when it comes to writing trustworthy systematic reviews
Human researchers outperformed large language models across all major stages of systematic review preparation, particularly in study selection, synthesis, and final manuscript drafting. While LLMs demonstrated speed and partial accuracy in early screening and data extraction, they could not independently produce high-quality, guideline-compliant systematic reviews.
Walking speed before surgery predicts who thrives after hip replacement
This study shows that preoperative gait speed is a strong predictor of patient-reported pain relief, function, and joint awareness after total hip arthroplasty for osteoarthritis. A walking speed of at least 1.0 m/s before surgery independently predicts excellent postoperative outcomes.
Early exposure to fat-related food smells increases lifelong obesity risk
Early exposure to fat-related food odors during development alters central sensory processing and metabolic regulation, independently of maternal obesity or nutrient intake. These sensory cues program long-term susceptibility to obesity, impaired thermogenesis, and altered brain responses to dietary fat in adulthood.
Smartphone motor tests can predict dopamine deficiency in Parkinson’s disease without brain scans
Researchers explore the use of smartphones coupled with clinical scores to evaluate motor function and predict dopamine deficiency.
Fixed-duration therapy works as effectively as continuous treatment for chronic lymphocytic leukemia
According to a new trial, patients with chronic lymphocytic leukemia (CLL) show comparable outcomes whether they receive a single-agent treatment indefinitely or a combination treatment for a fixed period of time.
Chemotherapy-based conditioning matches outcomes of total body irradiation for MRD-negative B-ALL
In a new trial, patients with B-acute lymphoblastic leukemia (B-ALL) who had no evidence of remaining cancer cells after prior treatment, experienced comparable outcomes whether they received chemotherapy-based conditioning or total body irradiation (TBI), the standard conditioning regimen used before hematopoietic cell transplantation.
Many families of children with leukemia face significant financial hardship during treatment
Nearly a third of families with children receiving chemotherapy for acute lymphoblastic leukemia (ALL) – the most common pediatric cancer – develop serious financial difficulties during their child's treatment, including losing 25% or more of their household income and struggling to cover the costs of basic living expenses such as housing, food, and utilities.
Quality improvement project dramatically boosts iron deficiency screening in pregnancy
Within a year of initiation, a multidisciplinary project to improve screening and treatment for iron deficiency in pregnancy resulted in a sixfold rise in screening rates for iron deficiency in pregnant patients, a 20-fold rise in the number of intravenous (IV) iron infusions, and a significant improvement in median hemoglobin levels.
Intravenous iron shows safe and beneficial outcomes for patients with bacterial infection and anemia
Treatment with intravenous (IV) iron significantly improved survival and increased hemoglobin levels in patients with iron-deficiency anemia who were hospitalized for an acute bacterial infection, according to an analysis of data from more than 85,000 patients.
Black patients with AML experience earlier onset and poorer outcomes
Compared with white patients, Black patients with acute myeloid leukemia (AML) were on average more than five years younger at diagnosis, more than 30% more likely to die of their disease, and more than 20% more likely to die of any cause, according to an analysis of data conducted over a 34-year period and supported by the National Cancer Institute (NCI) is a component of the U.S. National Institutes of Health.




