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DNA Script expands access to on-demand DNA synthesis in India through distributor agreement with Imperial Life Sciences
DNA Script, the programmable biology company developing next-generation enzymatic DNA synthesis (EDS) technologies, today announced a new distribution agreement with Imperial Life Sciences (ILS), expanding access to the Company's SYNTAX platform across India.
Maternal diets high in UPFs may influence children’s health years later
A narrative review of 84 publications links higher ultra-processed food intake during pregnancy and early childhood with poorer diet quality, maternal complications, childhood obesity, and potential immune, metabolic, and neurodevelopmental effects. The authors identify possible microbiome and biopsychosocial pathways but emphasize that the predominantly observational evidence cannot establish causality.
Blood p-tau217 levels signal cognitive impairment risk years before symptoms emerge
Higher baseline plasma p-tau217 was associated with greater 5- and 10-year risks of cognitive impairment and faster cognitive decline among 2,684 cognitively unimpaired adults. Very high levels corresponded to an estimated 38% risk at five years, but selected cohorts and limited long-term data mean routine screening and individualized prediction remain premature.
Timing of regenerative cues may be key to better healing from injury
For decades, medicine has chased a simple but elusive goal of delivering the right drug to the right place at the right time.
New approach enhances radiotherapy by disabling cancer's DNA repair machinery
Cancer treatments like radiation and chemotherapy work by doing one main thing: shredding the DNA of cancer cells so they can no longer multiply.
LIG1 loss reveals new treatment strategy for aggressive breast cancer
Loss of one copy of the DNA Ligase I (LIG1) gene in triple-negative breast cancers (TNBC) with TP53 mutations confers resistance to chemotherapy, but researchers at Baylor College of Medicine and collaborating institutions have identified a vulnerability in these cells and used it to their advantage.
Researchers identify new genetic pathway driving epilepsy and seizures
Researchers have uncovered a novel biological pathway that can lead to seizures when disrupted. The findings also provide a new approach to improve the diagnosis of epilepsy, for which a genetic cause cannot be found in about 50 % of individuals with the condition
Immune pathway may promote the progression of oral precancerous lesions
Researchers at The University of Texas MD Anderson Cancer Center identified an immune pathway that may promote the progression of oral precancerous lesions into head and neck squamous cell carcinoma.
New model improves short- and long-term disease risk prediction
Researchers developed ALADYNOULLI, a Bayesian generative model that combines longitudinal health records, age, and polygenic risk to identify reproducible disease signatures across more than 683,000 participants. In UK Biobank testing, the framework achieved stronger short- and long-term risk discrimination than established clinical scores while revealing disease subgroups and genetic associations.
Targeting ZBP1 may overcome cancer immunotherapy resistance
A new Review published in the open-access journal Ferroptosis and Oxidative Stress highlights Z-nucleic acid-binding protein 1 (ZBP1) as an emerging innate immune sensor that converts genomic stress into potent antitumor immunity.
Online harassment and screen time linked to suicidal thoughts
In the digital age, adolescents and young adults increasingly form social connections through online spaces, including social media, gaming and messaging platforms, which serve as venues for identity exploration, peer connection and emotional validation.
Targeting CMPK2-intervened redox metabolism to mitigate hepatic ischemia-reperfusion injury
HIRI is a major clinical challenge that occurs when blood supply to the liver is temporarily interrupted and then restored, as commonly seen in liver resection and liver transplantation.
Study highlights communication gaps between cancer survivors and providers on cannabis
For many cancer survivors, cannabis has become part of how they manage symptoms such as pain, nausea and anxiety.
Researchers identify immune cell receptor that drives organ aging process
We may age at different rates, but none of us escapes aging. A study in mice and in human cells by Stanford Medicine researchers pins much of the blame on a particular type of immune cell's increased inability, with advancing age, to gobble up another immune cell type.
Single-cell analysis identifies key regulators of cancer metastasis
By analyzing individual cancer cells, researchers from the Université Libre de Bruxelles (ULB) discovered the transcriptional regulators governing EMT in tumors and identified key master regulators that control metastasis, unraveling novel therapeutic vulnerabilities to block metastatic dissemination.
Fractional COVID booster doses provide strong long-lasting immunity
Smaller doses of COVID-19 booster vaccines can provide long-lasting immunity, helping to reduce costs and improve access to vaccination, according to new research. And the findings could also inform vaccine dosing and options during future pandemics.
Early PFAS exposure linked to childhood intestinal inflammation
Researchers at the Icahn School of Medicine at Mount Sinai have found that exposure to per- and polyfluoroalkyl substances (PFAS), commonly known as "forever chemicals," during pregnancy and early life is associated with increased intestinal inflammation during childhood.
Blood-based gene tests show promise for pancreatic cancer screening
Researchers at Kanazawa University report the blood-based gene expression tests may enable early pancreatic cancer screening and improve long-term survival.
Brain signals explain speech communication differences in autistic children
Why do some children with autism communicate more easily than others, even when they hear the same words?
New biological feedback loop helps the immune system attack colorectal cancers
A subset of cancers, known as microsatellite instability (MSI) and deficient DNA mismatch repair (dMMR) cancers, are more visible to the immune system than others.




