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Pheasants linked to higher risk of Lyme disease bacteria in ticks
Ticks are more likely to carry the bacteria that can cause Lyme disease in areas where pheasants are released, new research shows.
The lasting impact of paternal depression on children
In popular culture, dads are stoic, sensitive and strong. So powerful is the mystique of the happy dad that celebrities, joke books – even hard seltzers – carry the label.
New therapeutic frontiers in the management of achondroplasia
A recent publication in Genes & Diseases has delivered a compelling synthesis of the latest insights into the cellular mechanisms and therapeutic interventions for achondroplasia, the most common form of genetic dwarfism.
Molecular drivers and emerging treatments in anaplastic thyroid cancer
Anaplastic thyroid cancer (ATC), a rare yet highly aggressive malignancy, continues to represent a major clinical challenge.
GOT2 as a metabolic and immunologic target in pancreatic cancer
A new wave of scientific interest is spotlighting GOT2—glutamic-oxaloacetic transaminase 2—as a compelling therapeutic target in the fight against pancreatic cancer, one of the most lethal and treatment-resistant malignancies.
Reversing adipose tissue fibrosis through targeted microRNA therapies
A new review published in Genes & Diseases highlights the transformative role of microRNAs (miRNAs) in regulating and potentially reversing adipose tissue fibrosis, a condition closely linked to obesity, diabetes, and cardiovascular disease.
Exploring citrullination as a key regulator of gene expression and disease
Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.
Lipid metabolism as a driver of therapy resistance in triple negative breast cancer
Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC).
Redefining cardiovascular medicine through the lens of sncRNAs
In a transformative review, small noncoding RNAs (sncRNAs) have emerged as pivotal regulators in the complex landscape of cardiovascular diseases.
Unmasking Nrf2 as a key driver of treatment resistance in osteosarcoma
A deeper understanding of osteosarcoma, the most common primary malignant bone tumor affecting children and adolescents, is reshaping strategies for overcoming treatment resistance.
Traditional BMI cut-offs overestimate overweight and obesity in male athletes
New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) shows that the internationally recognized body mass index (BMI) cut-off points greatly overestimate overweight and obesity in male athletes.
Opioid control policies linked to drop in domestic violence
A new study led by the University of South Florida reveals opioid control policies may offer broader public health benefits, including reducing instances of domestic violence.
Using AI to understand how the brain processes language during real-life conversations
We investigated how our brains process language during real-life conversations. Specifically, we wanted to understand which brain regions become active when we're speaking and listening, and how these patterns relate to the specific words and context of the conversation.
The brain's visual system plays a bigger role in decision making than expected
When you see a bag of carrots at the grocery store, does your mind go to potatoes and parsnips or buffalo wings and celery?
Insurance instability more common among low-income adults with diabetes
An Oregon Health & Science University-led study reveals that low-income adults with diabetes are more likely to go in and out of health insurance, and that insurance instability is even worse for those with complex needs.
Scientists track liquid to solid shift in brain disease proteins
An international research collaboration led by Rutgers University-New Brunswick scientists that examined microscopic blobs of protein found in human cells has discovered that some morph from an almost honey-like substance to a hard candy-like solid.
Targeting PGM3 offers new hope against deadly brain tumor
Researchers have found that targeting an enzyme called PGM3 can help stop the growth of glioblastoma, the most dangerous type of brain tumor.
Monell study offers renewed hope for people living with Bardet-Biedl Syndrome
A Monell Chemical Senses Center study published this week in the Journal of Clinical Investigation offers renewed hope for individuals living with Bardet-Biedl Syndrome (BBS), a rare genetic disorder characterized by early-onset obesity, compulsive eating, and cognitive impairments.
Medical debt linked to increased likelihood of forgoing mental health care
People with medical debt in 2023 were about five times more likely to forgo mental health care treatment in the following year due to cost, compared to those without medical debt, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.
Study highlights the importance of clean water and sanitation in controlling endemic cholera
Public health strategies, from vaccination to improving sanitary conditions, may have different impacts depending on whether a disease is endemic - persisting in a particular location for an extended period of time - or a new outbreak, because the dominant transmission routes may differ, according to a new study.