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Proteomic signatures reveal early signs of cardiovascular-kidney-metabolic disease in children
Researchers at Vanderbilt Health, UTHealth Houston and the University of North Carolina at Chapel Hill have identified early signs of cardiovascular-kidney-metabolic disease (CKMD) in children as young as 8 years old that potentially can be reversed with a new class of weight loss drugs used widely by adults
McMaster researchers discover molecular switch causing dangerous blood clots
A cross-campus team of McMaster University researchers has identified why some patients develop dangerous blood clots after exposure to a common blood thinner – and a potential way to prevent it.
SIMS for enriched medical isotope targets
Hiden Analytical has published a technical article exploring how Secondary Ion Mass Spectrometry, SIMS, can support isotope ratio analysis and depth-resolved characterization of enriched medical isotope target materials.
AI identifies hidden biological patterns to accurately diagnose migraines
AI can trawl vast amounts of health data which is not specifically related to migraines, but which can be used to identify people predisposed to the condition.
Early studies hint that ketones may affect pathways linked to PTSD
An integrative review found that ketogenic therapy may influence metabolic, inflammatory, oxidative stress, and neurotransmitter pathways implicated in PTSD, with animal studies and small human studies reporting early signs of symptom improvement. Human evidence remains limited to very small cohorts, case reports, and pilot studies, and controlled trials have yet to establish clinical efficacy.
People with ADHD face higher odds of gastrointestinal problems
University of Warwick researchers have analyzed data from over 1.9 million people across 23 studies and found that ADHD is linked to an almost 50% increase in overall gastrointestinal symptoms compared with people without ADHD The association was even stronger for specific problems: nearly double the odds of constipation, a 58% increase in irritable bowel syndrome, and more than four times the odds of encopresis (loss of bowel control).
Study links eyelash extensions to skin mites, eye irritation and blocked glands
A study among young women who regularly have eyelash extensions has found most have tiny mites, called Demodex folliculorum, living on their lashes. These mites can cause a painful reaction in the skin called demodicosis.
Common medications trigger potentially harmful prescribing cascades in older adults
A new Ontario-wide study reveals that common medications, from statins to iron supplements, are quietly setting off prescribing cascades that leave older adults unknowingly taking drugs to treat side effects of other drugs.
Childhood chemotherapy leaves lasting DNA damage in healthy cells
Chemotherapy, which saves the lives of many children with cancer, causes previously unknown DNA alterations in the liver and leaves genetic footprints in other healthy cells as well.
Laser therapy offers new hope for inoperable pancreatic tumors
UCI Health, the clinical enterprise of the University of California, Irvine, is conducting a first-in-human, phase 1 clinical trial using laser light to target localized but inoperable pancreatic tumors to help patients become cancer free.
Coffee after colorectal cancer? Decaf and caffeine show different links with mortality
In a prospective analysis of 1,098 people with colorectal cancer, researchers found no significant association between total or caffeinated coffee intake and all-cause or colorectal cancer-specific mortality in the cohort overall. Decaffeinated coffee was associated with lower all-cause mortality, while the highest quartile of caffeine intake was associated with lower all-cause and colorectal cancer-specific mortality, although the observational study cannot establish causation.
Healthy checkout ordinance linked to lower soda and candy sales
A new study found that a healthy checkout ordinance implemented in Berkeley, Calif. supermarkets, drug stores, and mass-market retailers in 2021 was linked to notable decreases in soda sales overall and small-package candy in supermarkets, but greater enforcement of such policies is essential for sustained and meaningful public health benefit.
Study uncovers dynamic brain coding during decision-making
A new study by neuroscientists in The Picower Institute for Learning and Memory at MIT shows how the brain encodes information throughout the decision-making process to keep options clearly in mind and to ensure that chosen and unchosen options are remembered.
Chronic interferon exposure drives immunosuppression in tumors
Cancer biology and, in turn, cancer treatment have come a long way in the last few decades. Most people recognize this progress in breakthroughs like immunotherapy-a treatment strategy first deployed in 2011 that leverages the body's own immune cells to fight cancer and revolutionized the treatment landscape.
Refined starch activates immune pathways after low-carb weight loss
After substantial weight loss on a very-low-carbohydrate diet, participants who switched to a diet rich in refined starch showed greater activation of circulating immune and metabolic pathways than those who continued the low-carbohydrate diet or consumed a high-carbohydrate diet rich in added sugar. Mouse experiments suggested that activation of the complement immune pathway may help explain the inflammatory response associated with starch intake.
Strength training shows no added arrhythmia risk in people with arrhythmogenic cardiomyopathy
People living with arrhythmogenic cardiomyopathy (ACM), a heritable heart condition that can significantly increase risks for sudden cardiac death, are advised to avoid high-intensity aerobic exercise.
Study reveals hidden DNA damage from childhood chemotherapy
The amount of DNA damage caused by certain chemotherapies used to effectively treat childhood cancer has been revealed, along with a hidden impact on the liver, paving the way for future research into new ways to mitigate these impacts.
Brain interference explains why multitasking becomes difficult
Multitasking feels like a required skill in modern life, but as anyone who has tried keeping track of multiple chat windows, an email inbox, and a stream of phone notifications during a video call can tell you, figuring out which messages are important comes at a cost.
Prediabetes linked to substantial burden of mental health conditions
Announcing a new article publication for BIO Integration. Prediabetes has a high prevalence worldwide; however, the prevalence of mental health conditions within the population with prediabetes is not well understood.
Women use creatine differently from men, survey reveals
A cross-sectional survey of 2,094 current or recent creatine users found that women were more concentrated in shorter-duration use groups than men and reported different supplementation goals, information sources, and knowledge patterns. Women were less likely to cite athletic performance and more likely to cite healthy aging as a goal, while researchers cautioned that the survey design cannot explain why these differences exist.




