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Study sheds light on brain circuit behind auditory hallucinations in schizophrenia
Voice experiments in people with epilepsy have helped trace the circuit of electrical signals in the brain that allow its hearing center to sort out background sounds from their own voices.
Loss of empathy in frontotemporal dementia linked to brain activity changes
Patients with frontotemporal dementia often lack the ability to empathize. A study at Karolinska Institutet has now shown that these patients do not show the same brain activity as healthy individuals when they witness the pain of others, a finding that it is hoped will increase understanding of this specific dementia disease.
CBT and rehabilitation show modest benefits for long COVID recovery, study finds
CBT and combined rehabilitation offer moderate benefits for long COVID, enhancing quality of life and reducing fatigue, but evidence quality is variable.
PCORI funds $156 million for new patient-centered comparative clinical effectiveness research
The Patient-Centered Outcomes Research Institute (PCORI) has approved funding awards totaling more than $156 million for new patient-centered comparative clinical effectiveness research (CER), as well as research to improve methods and strengthen the science of engagement in CER.
Scientists aim to identify the most effective TBS protocols for treating schizophrenia
Schizophrenia, which is characterized by positive symptoms (e.g., hallucinations and delusions), negative symptoms (diminished emotional expressions or avolition), and cognitive impairments (attention deficits and poor learning skills), is a serious mental health condition that affects how individuals think, behave, and perceive the world.
Minimally invasive procedure provides relief for knee osteoarthritis sufferers
A minimally invasive procedure provides significant relief from knee pain and may prevent the need for knee replacement surgery in people with osteoarthritis, according to a study being presented this week at the annual meeting of the Radiological Society of North America (RSNA).
Gut microbes may have helped human ancestors develop larger brains
Brain tissue is among the most energetically costly in the body, and as a result, larger-brained mammals require more energy to support brain growth and maintenance.
Lifestyle choices and cognitive health linked to future dementia risk
The risk of developing dementia later in life is strongly predicted by a person's cognitive ability, functional limitations and physical health as many as 20 years before onset of the illness, according to a new RAND report.
Skeletal muscle loss linked to increased risk of dementia
Skeletal muscle loss is a risk factor for developing dementia, according to a study being presented today at the annual meeting of the Radiological Society of North America (RSNA).
Research sheds light on how mutated PSEN2 accelerates familial Alzheimer's disease progression
Alzheimer's disease is a debilitating condition that slowly robs people of their memory and cognitive abilities, affecting millions of people worldwide.
Brain scan could predict success of spinal surgery for chronic pain
A 10-minute brain scan can predict the effectiveness of a risky spinal surgery to alleviate intractable pain. The Kobe University result gives doctors a much-needed biomarker to discuss with patients considering spinal cord stimulation.
Study links menopause hormone therapy to varied heart and blood clot risks
Research on hormone therapy reveals critical insights into cardiovascular disease risks, guiding clinicians in selecting safer treatment options for menopause.
Orbit Discovery and Evergreen Theragnostics expand research collaboration to advance targeted therapeutics development
Orbit Discovery, a leading provider of peptide discovery services, and Evergreen Theragnostics, a radiopharmaceutical company at the forefront of precision medicine, today announced an extension to their research collaboration to find novel targeting peptides for radiopharmaceutical delivery.
Key risk factors influencing mortality rates in chronic pulmonary aspergillosis patients
A systematic review reveals chronic pulmonary aspergillosis mortality is driven by age and underlying conditions, highlighting the need for targeted therapies.
Peptidomimetics as a new strategy to modulate Aurora-A and combat cancer
A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights into how it functions.
Biocompatible liquid ink enables scalp-printed electrodes for non-invasive EEG
For the first time, scientists have invented a liquid ink that doctors can print onto a patient's scalp to measure brain activity. The technology, presented December 2 in the Cell Press journal Cell Biomaterials, offers a promising alternative to the cumbersome process currently used for monitoring brainwaves and diagnosing neurological conditions. It also has the potential to enhance non-invasive brain-computer interface applications.
A roadmap for improving cancer care in South Asia
A series of five papers, published today in The Lancet Oncology by a University of Pittsburgh-led international team, highlights critical public health challenges related to cancer control in the eight countries that form the South Asian Association for Regional Cooperation (SAARC) and the Rohingya refugee population in Bangladesh.
Overcoming challenges in developing cell therapies for heart disease
Pathways to new treatments for heart failure take time -; as long as four decades for two now accepted therapies. So, new attempts to repair scar tissue in infarcted hearts using cells or cell products need more time to develop clinical therapies that can reduce risk of death from heart failure after a heart attack.
Fas-p53 pathway drives metabolic dysfunction and obesity-linked insulin resistance
Researchers unveil Fas-p53 axis as a key regulator in adipocyte metabolism, linking it to obesity and insulin sensitivity through energy expenditure and inflammation pathways.
Greening cities saves lives and transforms urban health
Increasing urban green spaces in Italy could prevent 28,433 deaths annually, highlighting their critical role in reducing mortality and improving public health.