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New hope for sclerosteosis patients through Wnt pathway inhibition

Rss Feed - Wed, 04/16/2025 - 21:30
Sclerosteosis arises from mutations in the SOST gene, causing abnormally high bone mass and skeletal overgrowth, which can lead to severe health issues such as hearing loss and increased intracranial pressure.

Listening to favorite music activates the brain’s opioid system

Rss Feed - Wed, 04/16/2025 - 21:27
A new imaging study by the Turku PET Centre in Finland showed that listening to favorite music affects the function of the brain's opioid system.

Ethnicity and socioeconomic deprivation linked to adverse birth outcomes

Rss Feed - Wed, 04/16/2025 - 21:09
In Birmingham, 43% of the population live in the most deprived 10% of neighborhoods in England. It is well known that deprivation can lead to adverse pregnancy outcomes, including low birth weight, premature birth, stillbirths, and neonatal mortality.

Prolonging pain relief in surgery with dexmedetomidine and spinal anesthesia

Rss Feed - Wed, 04/16/2025 - 20:58
Spinal anesthesia is widely used to numb patients during surgery, but its effects sometimes wear off too soon.

Comparing single cell RNA methods to improve gastrointestinal cancer research

Rss Feed - Wed, 04/16/2025 - 20:55
Research on gastrointestinal diseases, especially cancer, has mainly looked at the epithelial cells, which line the surfaces of organs, are important for various functions, and are believed to be the cells that go awry to cause these diseases.

Early detection of Alzheimer's disease through blood biomarker

Rss Feed - Wed, 04/16/2025 - 14:09
Individuals with a genetic predisposition to Alzheimer's disease show altered blood levels indicating damaged neuronal contacts as early as 11 years before the expected onset of dementia symptoms.

Breakthrough method creates functional liver organoids

Rss Feed - Wed, 04/16/2025 - 14:02
While organoids aim to mimic human organs, the liver's repertoire of complex functions – and thus the energy it needs to operate – have made it challenging for researchers to grow organoids that proliferate and fully function, says Sato. When prioritizing growth and survival in laboratory settings, hepatocytes, the liver's main cells, eventually transformed into cells resembling cholangiocytes, which line the bile duct.

Breakthrough method allows stem cell treatment for critically ill patients on ECMO

Rss Feed - Wed, 04/16/2025 - 13:56
A multidisciplinary clinical team led by Professor Bernat Soria from the Institute of Bioengineering at the Miguel Hernández University of Elche (UMH, Spain) has developed a new method to deliver cell therapies in patients on extracorporeal membrane oxygenation (ECMO), a life support system used in cases of severe lung failure.

Brisk walking linked to lower risk of heart rhythm disorders

Rss Feed - Wed, 04/16/2025 - 13:46
A brisk walking pace, and the amount of time spent at this speed, may lower the risk of heart rhythm abnormalities, such as atrial fibrillation, tachycardia (rapid heartbeat), and bradycardia (very slow heartbeat), finds research published online in the journal Heart.

Male survivors of intimate partner violence struggle with isolation and stigma

Rss Feed - Wed, 04/16/2025 - 13:16
Men experiencing intimate partner violence turn to harmful coping strategies due to limited services and persistent social stigma, according to a new Simon Fraser University study.

Early menopause linked to worse cognitive function in later life

Rss Feed - Wed, 04/16/2025 - 13:08
A team of researchers from the Tohoku University Graduate School of Medicine and Tokyo Metropolitan Institute of Medical Science found that women who entered menopause before the age of 40 had worse cognitive outcomes than women who entered menopause after the age of 50.

Nature based activities improve mental health in just twelve weeks

Rss Feed - Wed, 04/16/2025 - 13:01
Researchers evaluating a nature-based programme of activities for patients with mild to moderate mental health conditions have shown that improvements in mood and anxiety levels can be seen in as little as 12 weeks.

Mitochondria found to fuel dangerous growth in aging blood stem cells

Rss Feed - Wed, 04/16/2025 - 12:55
As we age, blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations.

Study links cold hypersensitivity and heaviness in legs to varicose veins

Rss Feed - Wed, 04/16/2025 - 12:39
Hypersensitivity to the cold, especially ice cold feet, as well as a feeling of heaviness in the legs, are linked to the presence of varicose veins, finds a large study published in the open access journal Open Heart.

Study sheds light on brain regions involved in logical thinking

Rss Feed - Wed, 04/16/2025 - 12:35
A team of researchers at UCL and UCLH have identified the key brain regions that are essential for logical thinking and problem solving.

Medicaid expansion improves access to high-volume hospitals for lung cancer patients

Rss Feed - Wed, 04/16/2025 - 12:32
A new study published in The Annals of Thoracic Surgery, the flagship journal from The Society of Thoracic Surgeons, suggests that Medicaid expansion under the Affordable Care Act has significantly improved access to timely treatment and high-volume hospitals for patients with early-stage non-small cell lung cancer (NSCLC).

Music therapy intervention improves mental health for heart failure and COPD patients

Rss Feed - Wed, 04/16/2025 - 12:27
A new study from University Hospitals Connor Whole Health found that it was feasible to conduct a hybrid music therapy intervention for patients with heart failure and patients with chronic obstructive pulmonary disease (COPD).

Study identifies brain area linked to social behavior and altruism

Rss Feed - Wed, 04/16/2025 - 08:10
Are there areas of the brain, which regulate prosocial, altruistic behaviour? Together with colleagues from the universities in Lausanne, Utrecht and Cape Town, researchers from Heinrich Heine University Düsseldorf (HHU) have studied a very special group of patients and established that the "basolateral amygdala" (part of the limbic system) plays an important role in this.

Early combination treatment can prevent heart attacks and save lives

Rss Feed - Wed, 04/16/2025 - 07:38
Patients who receive an add-on medication soon after a heart attack have a significantly better prognosis than those who receive it later, or not all.

What sauerkraut can do for your gut

Rss Feed - Wed, 04/16/2025 - 06:52
Fermented cabbage metabolites play a crucial role in maintaining gut barrier function, suggesting potential health benefits for inflammatory disorders.

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