Feed aggregator

Men diagnosed with nonmetastatic prostate cancer can generally expect to live for many years after their diagnosis. However, cardiovascular disease and other cancers remain important threats to their long-term health.

A genetic marker already used to flag risk of a life-threatening reaction to the antibiotic vancomycin also identifies patients at risk of that reaction to lamotrigine - and it is missing from the gene panels clinicians order before prescribing the drug, Vanderbilt Health-led researchers report Sept. 2 in JAMA Network Open.

An international consortium of researchers found that more than 1,200 different genetic variants are associated with the Big Five personality traits - and surprisingly, these personality genetics are linked to dozens of life outcomes.

A team from UNIGE and HUG has shown that administering cell immunotherapy before surgery to remove a brain tumor is significantly more effective than administering it afterwards.

More attention than ever is being paid today to midlife women's health, including the menopause transition.

Researchers at AIST, in collaboration with the University of Texas Southwestern Medical Center in the United States, examined changes in brain activity during cognitive tasks before and after acute aerobic exercise in young and older healthy adults.

A recent study in the Journal of Nutrition Education and Behavior (JNEB), published by Elsevier, explored elementary school teachers' experiences before and after the end of the federal universal free school meals (UFSM) policy.

A Rutgers-led international collaboration has identified 36 genes that substantially raise the risk for obsessive-compulsive disorder (OCD) and chronic tic disorders – providing what two researchers said is the most detailed biological understanding of how these conditions develop – and how they might eventually be treated.

A bacterial protein fragment called corisin drives the process of pulmonary fibrosis by infiltrating and disrupting the cell's quality-control system, researchers at the University of Illinois Urbana-Champaign and Mie University in Japan found in a new study.

Regular aerobic exercise – the kind that gets your heart pumping – can improve important thinking skills called executive functions, and the benefits appear especially strong for women after menopause, according to Rutgers researchers.

Around one in four heart surgery patients develop serious lung complications – but a new Adelaide-led study is testing a simple bedside scan that could predict who is most at risk before symptoms appear.

Researchers at VIB, VUB, and the Medical Research Council Laboratory of Molecular Biology (UK) have discovered a hidden feature of human sperm cells.

A scoping review of 91 studies, combined with a workshop involving 41 experts from six European countries, mapped the spread, biology, surveillance challenges, and potential disease relevance of the invasive mosquito Aedes koreicus. The researchers identified major gaps in species identification, vector competence, ecology, genetics, and long-term surveillance that must be addressed as the cold-tolerant mosquito expands across Europe.

Influenza viruses constantly shapeshift to evade recognition by the immune system. This shapeshifting occurs in critical proteins like hemagglutinin (HA), which controls how the virus attaches to human cells before entering them.

In 435,551 UK Biobank participants followed for a median of 15.7 years, overall coffee consumption was not associated with Parkinson’s disease risk, but the relationship differed significantly according to CYP1A2 genotype. Lower risk was observed with low-to-moderate coffee intake among fast-metabolizer AA carriers, while higher intake was associated with increased risk among AC and CC carriers, although the observational findings do not establish causality and sex-specific patterns require cautious interpretation.

A global analysis of GBD 2023 data found that alcohol-attributable liver cancer mortality increased modestly from 1990 to 2023, while mortality from alcohol-attributable cirrhosis, alcoholic cardiomyopathy, and alcohol use disorders declined. Liver cancer mortality shifted from a pre-pandemic decline to an increase during 2020–2023, particularly among women, although the researchers cautioned that the ecological analysis cannot establish that pandemic-related changes caused the reversal.

A global literature review and geostatistical modeling study estimated the burden of snake envenoming and deaths across countries, accounting for differences in surveillance, underreporting, socioeconomic conditions, and environmental factors. The analysis highlights major gaps in epidemiological data and provides updated country- and regional-level estimates to help guide prevention, antivenom access, surveillance, and healthcare resources.

University of Missouri researchers are advancing a promising new approach to treating a serious heart condition that affects millions of older adults worldwide.

Researchers have created a detailed map of childhood Crohn's disease before and after treatment to help understand progression of the disease.

Smartwatches can significantly overestimate how many calories people burn during exercise, and their calorie estimates become less accurate as body fat increases, according to a new Florida International University study.