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Treating glioblastoma with a class of drugs known as EGFR inhibitors made this cancer more sensitive to chemotherapy, suggests a study in preclinical models co-led by researchers at UT Southwestern Medical Center and the University of Alabama at Birmingham.

Gum disease bacteria may spur calcium buildup in the heart's aortic valve, leading to a common and serious heart valve disease, according to preliminary, independent research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2026.

A major, USC-led study of more than 214,000 older adults across 14 countries and regions finds that the most common controllable risk factors for dementia - such as low education, high blood pressure and smoking - vary widely from country to country, meaning a one-size-fits-all approach to prevention won't work everywhere.

PsyEval is a new benchmark that tests how large language models perform on mental health knowledge, diagnostic assessment, and emotional support tasks. The study found that leading models can show strong factual recall and fluent responses, but still struggle with empathy, clinical nuance, prompt sensitivity, and safe diagnostic behavior.

Maternal cold exposure during early pregnancy improved glucose control and reduced liver fat in male rat offspring, with benefits persisting into late adulthood. The findings implicate a breast milk LCA, gut microbiota, and Th17 immune pathway, while human cohort data showed an observational link between winter conception and lower MASLD risk.

A new study led by researchers at the Icahn School of Medicine at Mount Sinai found that although the overall number of radiation oncology clinics in the United States has appeared stable in recent years, many individual treatment centers have quietly closed while others have opened.

New research presented today at the International Society for Stem Cell Research (ISSCR) 2026 Annual Meeting explores an approach that could expand the potential of cell replacement therapy for type 1 diabetes by evaluating whether immune-engineered, allogeneic insulin-producing cells can survive and function without chronic immunosuppression.

Does informing people about their genetic risk of obesity help them change their habits and lose excess weight? A study, published in the journal Obesity Reviews by scientists including researchers from SWPS University, shows that knowledge about one's genes alone is not enough.

Oxalic acid might do more than just contribute to the formation of kidney stones — it may also be an underappreciated driver of inflammation and heart damage in people with impaired kidney function.

BET proteins, especially BRD4, drive oncogenic transcription in solid tumours. First‑generation inhibitors (JQ1, molibresib, birabresib) showed preclinical promise but failed clinically due to modest efficacy, dose‑limiting thrombocytopenia, and resistance (isoform switching, compensatory PI3K/AKT/WNT signalling).

A form of glioma, a type of brain cancer, tends to progress towards greater malignancy due to an increasing tendency of the glioma cells to transform into immature, stem-cell-like states, according to a study led by investigators at Weill Cornell Medicine, the New York Genome Center, Harvard Medical School and Mass General Brigham.

New research presented today at the International Society for Stem Cell Research (ISSCR) 2026 Annual Meeting highlights a significant step toward developing a stem cell-based treatment for chronic spinal cord injury (SCI), a condition for which no effective restorative therapy currently exists.

Air pollution from cruise ships could be damaging the health of people living in port cities by increasing inflammation and susceptibility to viruses such as the common cold and COVID-19.

A healthy bone marrow (BM) produces nearly all types of cells in our blood. Many blood disorders occur when hematopoietic stem cells (HSCs) in the BM malfunction.

In a global breakthrough published in Nature Genetics, researchers have successfully mapped the cells and genes that regulate bone formation and loss at an unprecedented scale and discovered the critical role that blood vessel cells play in bone health.

Research indicates GLP-1RAs may decrease limb complications in type 2 diabetes with PAD, though more randomized studies are required to confirm efficacy.

Investigating breast cancer and atrial fibrillation overlap, this study highlights key risk factors, underscoring the need for integrated prevention approaches.

A systematic review and meta-analysis of seven cohort studies involving more than 40,000 GLP-1 receptor agonist-exposed pregnancies found no statistically significant increase in major congenital malformations or several other adverse pregnancy outcomes. However, the evidence was low or very low certainty, and a urinary malformation signal based on unadjusted data requires cautious interpretation.

This review identifies maladaptive responses to frustrative non-reward as a potential mechanism underlying clinically significant irritability, particularly in youth. Animal studies reveal conserved behavioral responses, while human research links frustration to altered neural activity and highlights opportunities for cross-species treatment research.

Some people are more sensitive to low-frequency noise, such as from ventilation systems, heat pumps, wind turbines and transformers. Why is that?